Hemodialysis - From Basic Research to Clinical Trials

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The field of hemodialysis is subject to constant transformations due to continuous advances in techniques, biomaterials and devices. Based on international surveys, objective evaluations of experts and recent clinical trials, the publication at hand pays special attention to the physiological aspects of treatments as well as practical questions in the dialysis unit. Taking into account recent developments, an international group of contributors addresses issues related to vascular access, epidemiology, inflammation, fluid management, uremic toxicity, treatment efficacy, advanced techniques, calcium/phosphate homeostasis, and correction of anemia. Focusing on basic and clinical aspects of innovative technology as well as on new therapeutic options, this publication is a most helpful tool for the clinician to keep abreast of developments in the field of hemodialysis.

Author(s): Claudio Ronco, Dinna N. Cruz
Series: Contributions to Nephrology
Edition: 1
Publisher: S. Karger AG (Switzerland)
Year: 2008

Language: English
Pages: 289

cover......Page 1
Contents-Preface.pdf......Page 2
1 Water Treatment for Dialysis Technology and Clinical Implications......Page 12
2 Dialysate Composition......Page 18
3 Challenge for the Interventional Nephrologist Monitoring the Arteriovenous Fistula......Page 23
4 Preoperative Hemodialysis Fistula Evaluation Angiography, Ultrasonography and Other Studies, Are They Useful......Page 34
5 Endovascular Procedures......Page 41
6 Optimal Management of Central Venous Catheters for Hemodialysis......Page 50
7 Trends in Medication Use and Clinical Outcomes in Twelve Countries Results from the Dialysis Outcomes and Practice Patterns Study (DOPPS......Page 59
8 Epigenetics and the Uremic Phenotype A Matter of Balance......Page 66
9 The Burden of Cardiovascular Disease in Patients with Chronic Kidney Disease and in End-Stage Renal Disease......Page 74
10 BNP and a Renal Patient Emphasis on the Unique Characteristics of B-Type Natriuretic Peptide in End-Stage Kidney Disease......Page 79
108 Body Composition and Outcomes in Chronic Hemodialysis Patients......Page 87
11 Potential Interplay between Nutrition and Inflammation in Dialysis Patients......Page 94
12 Microinflammation and Endothelial Damage in Hemodialysis......Page 101
13 Oxidative Stress and Anemia in Chronic Hemodialysis The Promise of Bioreactive Membranes......Page 107
14 Consequences of Overhydration and the Need for Dry Weight Assessment......Page 117
15 Whole-Body Spectroscopy (BCM) in the Assessment of Normovolemia in Hemodialysis Patients......Page 126
16 Blood Volume Monitoring......Page 130
17 From Uremic Toxin Retention to Removal by Convection Do We Know Enough......Page 136
18 Oxidative Stress in Hemodialysis......Page 143
19 Determinants of Insulin Resistance and Its Effects on Protein Metabolism in Patients with Advanced Chronic Kidney Disease......Page 149
20 What Is Important in Dialysis The Frequency of Treatment Sessions......Page 156
21 Treatment Time......Page 165
22 Membrane Characteristics......Page 173
23 What Is Important in Dialysis Efficiency Blood Flow, KoA and Kt-V......Page 179
24 Cross-Membrane Flux Is a Major Factor Influencing Dialysis Patient Outcomes......Page 189
25 Inflammatory Pattern in Hemodiafiltration......Page 196
26 Online Hemodiafiltration A Multipurpose Therapy for Improving Quality of Renal Replacement Therapy......Page 202
27 Biofeedback-Driven Dialysis Where Are We......Page 210
28 Calcium and Phosphorus Kinetics in Hemodialysis Therapy......Page 221
29 Impact of Ca-P Disorders on Risks and Comorbidities......Page 226
30 Diagnostic Procedures and Rationale for Specific Therapies in Chronic Kidney Disease-Mineral and Bone Disorder......Page 233
31 Preventive Measures and New Pharmacological Approaches of Calcium and Phosphate Disorders......Page 245
32 Insights in Anemia Management......Page 251
33 Red Blood Cell Lifespan, Erythropoiesis and Hemoglobin Control......Page 258
34 New Erythropoiesis-Stimulating Agents How Innovative Are They......Page 266
35 Is the Advent of Biosimilars Affecting the Practice of Nephrology and the Safety of Patients......Page 272
Author Indx......Page 282
Subject Index......Page 283