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Hematology: 101 Morphology Updates

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Hematology

Timely morphology resource based on ongoing series of morphology updates published in the American Journal of Hematology since 2008

This is the first book of its kind, written by renowned author Professor Barbara J. Bain, featuring a collection of instructive cases with interesting morphological features initially published in the American Journal of Hematology. This new book aims to bring these interesting and instructive cases to a wider readership. This book features updated cases and a “Test Yourself” section to aid in reader comprehension and information retention.

Cases covered in Hematology: 101 Morphology Updates include:

  • The significance of irregularly contracted cells and hemighosts in sickle cell disease, and striking dyserythropoiesis in sickle cell anemia following an aplastic crisis
  • Prominent Howell-Jolly bodies when megaloblastic anemia develops in a hyposplenic patient, and unusual aspects of G6PD deficiency
  • The cause of sudden anemia revealed by the blood film, chorea-acanthocytosis and dysplastic neutrophils in an HIV-positive woman
  • Neutrophil dysplasia induced by granulocyte colony-stimulating factor, and diagnosis of pyrimidine 5'-nucleotidase deficiency suspected from a blood film

Hematology: 101 Morphology Updates is a key resource for consultant hematologists and clinical scientists, trainee hematologists and biomedical scientists. The audience may use this book to solve difficult diagnostic problems or as a source of teaching cases: for both personal learning, including exam revision or solving difficult cases, and as a teaching resource.

Author(s): Barbara J. Bain
Publisher: Wiley-Blackwell
Year: 2023

Language: English
Commentary: identification watermark, cleaned version available
Pages: 172
City: Hoboken

Cover
Title Page
Copyright Page
Contents
Preface
Note to the reader
Acknowledgements
Abbreviations
Chapter 1 Malaria - one swallow makes a summer
Chapter 2 The significance of irregularly contracted cells and hemighosts in sickle cell disease
Reference
Chapter 3 Striking dyserythropoiesis in sickle cell anemia following an aplastic crisis
Chapter 4 A normal mean cell volume does not exclude a diagnosis of megaloblastic anemia
Reference
Chapter 5 Prominent Howell.Jolly bodies when megaloblastic anemia develops in a hyposplenic patient
Chapter 6 A ghostly presence – G6PD deficiency
Reference
Chapter 7 G6PD deficiency in patients identified as female
Chapter 8 The cause of sudden anemia revealed by the blood film
Chapter 9 Choreo-acanthocytosis
Reference
Chapter 10 Lead poisoning
References
Chapter 11 Dysplastic neutrophils in an HIV-positive woman
Reference
Chapter 12 Help with HELLP
Chapter 13 Neutrophil dysplasia induced by granulocyte colony-stimulating factor
References
Chapter 14 COVID-19 and acute kidney injury
References
Chapter 15 Diagnosis of pyrimidine 5' nucleotidase deficiency suspected from a blood film
Chapter 16 Bone marrow aspirate in Chédiak–Higashi syndrome
Chapter 17 Phytosterolemia
Reference
Chapter 18 Pseudo-Chédiak–Higashi inclusions together with Auer rods in acute myeloid leukemia
References
Chapter 19 Botryoid nuclei resulting from cocaine abuse
References
Chapter 20 Infantile pyknocytosis
References
Chapter 21 Splenic rupture in cytomegalovirus infection
References
Chapter 22 A new diagnosis of monoclonal B-cell lymphocytosis with cytoplasmic inclusions in a patient with COVID-19
Chapter 23 Pseudoplatelets and apoptosis in Burkitt lymphoma
References
Chapter 24 What is a promonocyte?
References
Chapter 25 Persistent neonatal jaundice resulting from hereditary pyropoikilocytosis
Reference
Chapter 26 Auer rods or McCrae rods?
References
Chapter 27 Observation of Auer rods in crushed cells in acute promyelocytic leukemia
Reference
Chapter 28 Alpha chain inclusions in peripheral blood erythroblasts and erythrocytes
Reference
Chapter 29 Dyserythropoiesis in visceral leishmaniasis
Reference
Chapter 30 Compound heterozygosity for hemoglobins S and D
Reference
Chapter 31 Granular B lymphoblastic leukemia
References
Chapter 32 Hyposplenism in adult T-cell leukemia/lymphoma
Chapter 33 Voxelotor in sickle cell disease
References
Chapter 34 The importance of a negative image
Chapter 35 Seeing what isn’t there
Chapter 36 A young woman with sudden onset of a severe coagulation abnormality
Chapter 37 Immature Plasmodium falciparum gametocytes in bone marrow
Reference
Chapter 38 Acute myeloid leukemia with myelodysplasia-related changes showing basophilic differentiation
References
Chapter 39 Thiamine-responsive megaloblastic anemia in an Iraqi girl
Chapter 40 Teardrop poikilocytes in metastatic carcinoma of the breast
Chapter 41 A blood film that could have averted a splenectomy
References
Chapter 42 Russell bodies and Mott cells
References
Chapter 43 Dutcher bodies
Reference
Chapter 44 Acute myeloid leukemia with inv(16)(p13.1q22)
Reference
Chapter 45 Dysplastic macropolycytes in myelodysplasia-related acute myeloid leukemia
Chapter 46 Diagnosis of cystinosis from a bone marrow aspirate
Chapter 47 Emperipolesis in a patient receiving romiplostim
References
Chapter 48 Mechanical hemolysis: a low mean cell volume does not always represent microcytosis
Chapter 49 Transplant-associated thrombotic microangiopathy
References
Chapter 50 Neuroblastoma in the bone marrow
Chapter 51 Gray platelet syndrome
Chapter 52 Diagnosis of systemic lupus erythematosus from a bone marrow aspirate
References
Chapter 53 Diagnosis from a blood film following a dog bite
Chapter 54 Interpreting a postpartum Kleihauer test
Chapter 55 Dengue fever in returning travellers
References
Chapter 56 Auer rod-like inclusions in multiple myeloma
References
Chapter 57 Azurophilic granules in myeloma cells
References
Chapter 58 Plasmodium knowlesi
Chapter 59 The cytological features of NPM1-mutated acute myeloid leukemia
References
Chapter 60 Irregularly contracted cells in Wilson disease
Chapter 61 Pseudo-Pelger–Huët neutrophil morphology due to sodium valproate toxicity
Chapter 62 The distinctive cytological features of T-cell prolymphocytic leukemia
Reference
Chapter 63 Eosinophil morphology in the reactive eosinophilia of Hodgkin lymphoma
Reference
Chapter 64 Malaria pigment
References
Chapter 65 Salmonella colonies in a bone marrow film
Chapter 66 Severe babesiosis due to Babesia divergens acquired in the UK
References
Chapter 67 Congenital acute megakaryoblastic leukemia
References
Chapter 68 Basophilic differentiation in transient abnormal myelopoiesis
Chapter 69 Methylene blue-induced Heinz body hemolytic anemia in a premature neonate
References
Chapter 70 Neutrophil vacuolation in acetominophen-induced acute liver failure
Chapter 71 Howell–Jolly bodies in acute hemolytic anemia
Chapter 72 The distinctive micromegakaryocytes of transformed chronic myeloid leukemia
Chapter 73 Copper deficiency
Chapter 74 Chronic neutrophilic leukemia
References
Chapter 75 Neutrophilic leukemoid reaction in multiple myeloma
References
Chapter 76 Persistent polyclonal B lymphocytosis
Chapter 77 Non-hemopoietic cells in the blood and bone marrow
References
Chapter 78 It’s a black day – metastatic melanoma in the bone marrow
References
Chapter 79 Dehydrated hereditary stomatocytosis
Chapter 80 Circulating lymphoma cells in intravascular large B-cell lymphoma
Chapter 81 Unusual inclusions in hemoglobin H disease post-splenectomy
Chapter 82 An unexpectedly bizarre blood film in hemoglobin H disease
References
Chapter 83 Acute myeloid leukemia with a severe coagulopathy and t(8;16)(p11;p13)
References
Chapter 84 Cold autoimmune hemolytic anemia secondary to atypical pneumonia
Chapter 85 A confusing ‘white cell count’ – circulating micromegakaryocytes in post-thrombocythemia myelofibrosis
Chapter 86 Diagnosis of follicular lymphoma from the peripheral blood
Chapter 87 Transformation of follicular lymphoma
Reference
Chapter 88 Cytology of systemic mastocytosis
Chapter 89 Systemic mastocytosis – the importance of looking within bone marrow fragments
Chapter 90 Schistocytosis is not always microangiopathic hemolytic anemia
Chapter 91 Hemoglobin C disease
Reference
Chapter 92 Hemoglobin St Mary’s
Reference
Chapter 93 Congenital sideroblastic anemia in a female
Reference
Chapter 94 A puzzling case of methemoglobinemia
Chapter 95 Hodgkin lymphoma in a bone marrow aspirate
Chapter 96 Giant proerythroblasts in pure red cell aplasia due to parvovirus B19 infection in a patient with rheumatoid arthritis
Chapter 97 A myeloid neoplasm with FIP1L1::PDGFRA presenting as acute myeloid leukemia
Reference
Chapter 98 Breast implant-associated anaplastic large cell lymphoma
Chapter 99 Large granular lymphocytosis induced by dasatinib
References
Chapter 100 The distinctive cytology and disease evolution of blastic plasmacytoid dendritic cell neoplasm
References
Chapter 101 Platelet phagocytosis as a cause of pseudothrombocytopenia
Test yourself
Answers to test cases
Index
EULA