Handbook of Optimization in Medicine is devoted to examining the dramatic increase in the application of effective optimization techniques to the delivery of health care. The articles, written by experts from the areas of operations research, computer science, and medicine, focus on models and algorithms that have led to more efficient and sophisticated treatments of patients. Topics covered include: optimization in medical imaging, classification and data mining with medical applications, treatment of epilepsy and other brain disorders, treatment of head-and-neck, prostate, and other cancers using conventional conformal and intensity-modulated radiation therapy as well as proton therapy, treatment selection for breast cancer based on new classification schemes, optimization for the genome project, optimal timing of organ transplants.
Author(s): P.M. Pardalos, H.E. Romeijn
Edition: 1
Year: 2008
Language: English
Pages: 451
0387097694......Page 1
Contents......Page 9
Preface......Page 7
List of Contributors......Page 11
1. Optimizing Organ Allocation and Acceptance......Page 14
2. Can We Do Better? Optimization Models for Breast Cancer Screening......Page 38
3. Optimization Models and Computational Approaches for Three-dimensional Conformal Radiation Treatment Planning......Page 66
4. Continuous Optimization of Beamlet Intensities for Intensity Modulated Photon and Proton Radiotherapy......Page 95
5. Multicriteria Optimization in Intensity Modulated Radiotherapy Planning......Page 135
6. Algorithms for Sequencing Multileaf Collimators......Page 180
7. Image Registration and Segmentation Based on Energy Minimization......Page 224
8. Optimization Techniques for Data Representations with Biomedical Applications......Page 264
9. Algorithms for Genomics Analysis......Page 302
10. Optimization and Data Mining in Epilepsy Research: A Review and Prospective......Page 335
11. Mathematical Programming Approaches for the Analysis of Microarray Data......Page 367
12. Classification and Disease Prediction via Mathematical Programming......Page 390
C......Page 440
E......Page 441
H......Page 442
I......Page 443
K......Page 444
M......Page 445
Q......Page 448
S......Page 449
U......Page 450
W......Page 451
