product iamge

Glycoscience Synthesis of Substrate Analogs and Mimetics

This document was uploaded by one of our users. The uploader already confirmed that they had the permission to publish it. If you are author/publisher or own the copyright of this documents, please report to us by using this DMCA report form.

Download
Search on Amazon

Simply click on the Download Book button.

Yes, Book downloads on Ebookily are 100% Free.

Sometimes the book is free on Amazon As well, so go ahead and hit "Search on Amazon"

The synthesis of very complex saccharide structures is one of the most challenging areas of modern glycoscience. This volume presents the state of the art of complex carbohydrate synthesis, written by leading scientists whose groups are making major contributions in the field. Reflecting the particular interest in inhibitors and modulators as well as in mimetics, an in-cepth treatment is given both of their selective syntheses and of their biological implications. In addition the concept of multivalent glycoconjugate recognition as well as supramolecular implications of amphiphilic carbohydrates are highlighted.

Author(s): Jean-Marie Beau, Timothy Gallagher (auth.), Dr. Hugues Driguez, Prof. Dr. Joachim Thiem (eds.)
Series: Topics in Current Chemistry 187
Edition: [Elektronische Ressource
Publisher: Springer Berlin Heidelberg
Year: 1997

Language: English
Pages: 329
Tags: Organic Chemistry; Biochemistry, general

Nucleophilic C-glycosyl donors for C-glycoside synthesis....Pages 1-54
Synthesis of C-glycosides of biological interest....Pages 55-83
Thiooligosaccharides in glycobiology....Pages 85-116
Aldonolactones as chiral synthons....Pages 117-156
Chemical and chemo-enzymatic approaches to glycosidase inhibitors with basic nitrogen in the sugar ring....Pages 157-186
The synthesis of novel enzyme inhibitors and their use in defining the active sites of glycan hydrolases....Pages 187-213
Heparinoid mimetics....Pages 215-239
Recent developments in the rational design of multivalent glycoconjugates....Pages 241-274
Amphiphilk carbohydrates as a tool for molecular recognition in organized systems....Pages 275-312