The nutraceutical and functional food field is rapidly growing in diverse sectors, including academic, commercial and government. This has brought a corresponding shift in research focus and in public awareness. Understanding the relevance of the scientific principles in determining the safety and effectiveness of functional foods and nutraceuticals is increasingly important. It is becoming increasingly evident that genomic research technologies will be used in the coming years and there is a need to provide resources that will facilitate this growth. This book incorporates the most recent advances in the three major sectors of the field within one volume. Genomics, proteomics, and metobolomics represent three major scientific research areas that contribute to nutraceutical and functional food research for studies of effectiveness and safety.
Author(s): Debasis Bagchi, Francis Lau, Manashi Bagchi
Edition: 1
Publisher: Wiley-Blackwell
Year: 2010
Language: English
Pages: 352
Genomics, Proteomics, and
Metabolomics in
Nutraceuticals and
Functional Foods......Page 4
Contents......Page 10
Editors and Contributors......Page 12
Preface......Page 16
Section 1 Introduction......Page 18
1. Recent advances in nutraceuticals and functional foods......Page 20
2. Novel omics technologies in nutraceutical and functional food research......Page 28
Section 2 Genomics......Page 40
3. Nutrigenomics and statistical power: The ethics of genetically informed nutritional advice......Page 42
4. NutrimiRomics: The promise of a new discipline in nutrigenomics......Page 52
5. Genomics in weight loss nutraceuticals......Page 62
6. Application of genomics and bioinformatics analysis in exploratory study of functional food......Page 78
7. Genomics as a tool to characterize anti-inflammatory nutraceuticals......Page 90
8. Application of nutrigenomics in gastrointestinal health......Page 100
9. Genomics analysis to demonstrate the safety and efficacy of dietary antioxidants......Page 112
10. Genomics applied to nutrients and functional foods in Japan: State of the art......Page 144
Color plate appears between pages 154 and 155.......Page 172
11. Genomic basis of anti-inflammatory properties of Boswellia extract......Page 188
12. Nutrigenomic Perspectives on Cancer Chemoprevention with Anti-inflammatory and Antioxidant Phytochemicals: NF-κB and Nrf2 Signaling Pathways as Potential Targets......Page 208
Section 3 Proteomics......Page 232
13. Proteomics analysis of the functionality of Toona sinensis by 2D-gel electrophoresis......Page 234
14. Application of proteomics in nutrition research......Page 246
15. Proteomics approach to assess the potency of dietary grape seed proanthocyanidins......Page 258
16. Proteomics and its application for elucidating insulin deregulation in diabetes......Page 274
Section 4 Metabolomics......Page 296
17. NMR-based-metabolomics strategy for the classification and quality control of nutraceuticals and functional foods......Page 298
18. Metabolomics: An emerging post-genomic tool for nutrition......Page 304
19. Evaluation of the beneficial effects of phytonutrients by metabolomics......Page 320
Section 5 Nutrigenomics in Human Health......Page 330
20. Omics for the development of novel phytomedicines......Page 332
21. Contribution of omics revolution to cancer prevention research......Page 348
Index......Page 362
