Genomics and Systems Biology of Mammalian Cell Culture

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Transcriptome Analysis, by Frank Stahl, Bernd Hitzmann, Kai Mutz, Daniel Landgrebe, Miriam Lübbecke, Cornelia Kasper, Johanna Walter und Thomas Scheper Transcriptome Data Analysis for Cell Culture Processes, by Marlene Castro-Melchor, Huong Le und Wei-Shou Hu Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, by Ziomara P. Gerdtzen Metabolic Flux Analysis in Systems Biology of Mammalian Cells, by Jens Niklas und Elmar Heinzle Advancing Biopharmaceutical Process Development by System-Level Data Analysis and Integration of Omics Data, by Jochen Schaub, Christoph Clemens, Hitto Kaufmann und Torsten W. Schulz Protein Glycosylation and Its Impact on Biotechnology, by Markus Berger, Matthias Kaup und Véronique Blanchard Protein Glycosylation Control in Mammalian Cell Culture: Past Precedents and Contemporary Prospects, by Patrick Hossler Modeling of Intracellular Transport and Compartmentation, by Uwe Jandt und An-Ping Zeng Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective, by L. Botezatu, S. Sievers, L. Gama-Norton, R. Schucht, H. Hauser und D. Wirth.

Author(s): Frank Stahl, Bernd Hitzmann, Kai Mutz (auth.), Wei Shou Hu, An-Ping Zeng (eds.)
Series: Advances in Biochemical Engineering Biotechnology 127
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2012

Language: English
Pages: 290
Tags: Biotechnology; Biochemistry, general; Cell Biology

Front Matter....Pages i-xxii
Transcriptome Analysis....Pages 1-25
Transcriptome Data Analysis for Cell Culture Processes....Pages 27-70
Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools....Pages 71-108
Metabolic Flux Analysis in Systems Biology of Mammalian Cells....Pages 109-132
Advancing Biopharmaceutical Process Development by System-Level Data Analysis and Integration of Omics Data....Pages 133-163
Protein Glycosylation and Its Impact on Biotechnology....Pages 165-185
Protein Glycosylation Control in Mammalian Cell Culture: Past Precedents and Contemporary Prospects....Pages 187-219
Modeling of Intracellular Transport and Compartmentation....Pages 221-249
Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective....Pages 251-284
Back Matter....Pages 285-288