Genetics is fundamental to hearing function, and an understanding of genetics enhances both auditory research and the clinical treatment of the hearing impaired. Approaches to the diagnosis and treatment of hearing impairment have developed from technological advances in genetic research. This volume covers gene expression, mutations, mapping and cloning, as well as mitochondrial and cellular genetics. Chapters are also included on the uses of mouse models, genetic epidemiology and genetic counseling specifically for hearing impairment. As a comprehensive review of the genetics of hearing, this book will interest hearing researchers, clinicians and genetic counselors.
Author(s): Bronya J. B. Keats, Charles I. Berlin (auth.), Bronya J. B. Keats, Richard R. Fay, Arthur N. Popper (eds.)
Series: Springer Handbook of Auditory Research 14
Edition: 1
Publisher: Springer-Verlag New York
Year: 2002
Language: English
Pages: 324
City: New York
Tags: Animal Physiology; Neurosciences; Human Physiology
Introduction and Overview: Genetics in Auditory Science and Clinical Audiology....Pages 1-22
Genes and Mutations in Hearing Impairment....Pages 23-44
Mapping and Cloning of Genes for Inherited Hearing Impairment....Pages 45-66
Genetic Epidemiology of Deafness....Pages 67-91
Cytogenetics and Cochlear Expressed Sequence Tags (ESTs) for Identification of Genes Involved in Hearing and Deafness....Pages 92-120
Autosomal and X-Linked Auditory Disorders....Pages 121-227
Hearing Loss and Mitochondrial DNA Mutations: Clinical Implications and Biological Lessons....Pages 228-246
Mice as Models for Human Hereditary Deafness....Pages 247-296
Genetic Counseling for Deafness....Pages 297-314
