10th Ed. 2013, 461 pages. InTeOpP, ISBN: 9535109945 9789535109945
This diverse collection of research articles is united by the enormous power of modern molecular genetics. Every author accomplished two objectives: (1) making the field and the research described accessible to a large audience and (2) explaining fully the genetic tools and approaches that were used in the research.
Read this book, you will learn about an area of research with which you may not be familiar. Perhaps most importantly, you will understand the genetic approaches; and you will appreciate their importance to the research.
Contents
Preface
Molecular Genetics in Basic Research
Site-Directed Mutagenesis and Yeast Reverse 2-Hybrid-Guided Selections to Investigate the Mechanism of Replication Termination
Biochemical Analysis of Halophilic Dehydrogenases Altered by Site-Directed Mutagenesis
Targeted Mutagenesis in the Study of the Tight Adherence (tad) Locus of Aggregatibacter actinomycetemcomitans
Directed Mutagenesis of Nicotinic Receptors to Investigate Receptor Function
Site-Directed Mutagenesis as a Tool to Characterize Specificity in Thiol-Based Redox Interactions Between Proteins and Substrates
Protein Engineering in Structure-Function Studies of Viper's Venom Secreted Phospholipases A2
Site-Directed Mutagenesis in the Research of Protein Kinases - The Case of Protein Kinase CK2
Directed Mutagenesis in Structure Activity Studies of Neurotransmitter Transporters
Site-Directed Mutagenesis as a Tool for Unveiling Mechanisms of Bacterial Tellurite Resistance
Molecular Genetics in Disease-Related Research
A Mutagenesis Approach for the Study of the Structure-Function Relationship of Human Immunodeficiency Virus Type 1 (HIV-1) Vpr
New Insights into the Epithelial Sodium Channel Using Directed Mutagenesis
Use of Site-Directed Mutagenesis in the Diagnosis, Prognosis and Treatment of Galactosemia
nherited Connective Tissue Disorders of Collagens: Lessons from Targeted Mutagenesis
Molecular Genetics in Applied Research
Biological Activity of Insecticidal Toxins: Structural Basis, Site-Directed Mutagenesis and Perspectives
Site-Directed Mutagenesis as Applied to Biocatalysts
New Tools or Approaches for Molecular Genetics
Using Cys-Scanning Analysis Data in the Study of Membrane Transport Proteins
Site-Directed Mutagenesis Using Oligonucleotide-Based Recombineering
Studying Cell Signal Transduction with Biomimetic Point Mutations
Using Genetic Reporters to Assess Stability and Mutation of the Yeast Mitochondrial Genome
Site-Directed and Random Insertional Mutagenesis in Medically Important Fungi
Recombineering and Conjugation as Tools for Targeted Genomic Cloning
