The 1st World Congress on Geriatrics and Neurodegenerative Disease Research (GeNeDis 2014), will focus on recent advances in geriatrics and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments and will provide an international forum for the latest scientific discoveries, medical practices and care initiatives. Advances information technologies will be discussed along with their implications for various research, implementation and policy concerns. In addition, the conference will address European and global issues in the funding of long-term care and medico-social policies regarding elderly people. GeNeDis 2014 takes place in Corfu, Greece, 10-13 April 2014. This volume focuses on the sessions that address neurodegenerative diseases.
Author(s): Panayiotis Vlamos, Athanasios Alexiou (eds.)
Series: Advances in Experimental Medicine and Biology 822
Edition: 1
Publisher: Springer International Publishing
Year: 2015
Language: English
Pages: 224
Tags: Neurosciences; Bioinformatics
Front Matter....Pages i-xiv
Molecular Neuropathology of Alzheimer Dementia and Therapeutic Approaches....Pages 1-1
Toxic Tau Aggregation in AD....Pages 3-9
RNA Binding Proteins and the Genesis of Neurodegenerative Diseases....Pages 11-15
Individual Severity of AD-Type Lesions, Aß Oligomers, and Comorbidity in the Brain Aging....Pages 17-17
The Influence of Immunomodulatory Treatment on the Clinical Course of Multiple Sclerosis....Pages 19-24
Notch Signaling and Ageing....Pages 25-36
Pro-oxidant DNA Breakage Induced by the Interaction of L-DOPA with Cu(II): A Putative Mechanism of Neurotoxicity....Pages 37-51
Superconductivity in Human Body; Myth or Necessity....Pages 53-58
Molecular Genetics of Huntington’s Disease....Pages 59-65
Altered Galectin Glycosylation: Potential Factor for the Diagnostics and Therapeutics of Various Cardiovascular and Neurological Disorders....Pages 67-84
Analytic Considerations and Axiomatic Approaches to the Concept Cell Death and Cell Survival Functions in Biology and Cancer Treatment....Pages 85-105
Possible Role of Resveratrol Targeting Estradiol and Neprilysin Pathways in Lipopolysaccharide Model of Alzheimer Disease....Pages 107-118
Synthesis and Antiepileptic Activity of Schiff’s Bases of Dialkylamino Alkoxy Isatin Derivatives....Pages 119-128
Synthesis and Screening of Biologically Significant 5-Hydroxy Isatin Derivatives for Antioxidant Activity....Pages 129-137
Modeling Neural Circuits in Parkinson’s Disease....Pages 139-147
Neuropathology of Parkinsonism in Alzheimer’s Disease....Pages 149-149
Towards an Expert System for Accurate Diagnosis and Progress Monitoring of Parkinson’s Disease....Pages 151-164
Kinesia Paradoxa: A Challenging Parkinson’s Phenomenon for Simulation....Pages 165-177
Towards the Development of a Device to Improve the Gait of Patients Suffering from Parkinson’s Disease....Pages 179-179
Adaptations in Aquatic Organisms for Increased Sensitivity to Light and Differences from Humans....Pages 181-186
The Impact of Physicochemical and Molecular Properties in Drug Design: Navigation in the “Drug-Like” Chemical Space....Pages 187-194
Advanced Drug Delivery Nanosystems: Perspectives and Regulatory Issues....Pages 195-198
Bio-inspired Chimeric Drug Delivery nano Systems (Chi-DDnSs): Their Fractal Hologram and Regulatory Aspects....Pages 199-200
Amphiphilic Cyclodextrin Nanoparticles for Effective and Safe Delivery of Anticancer Drugs....Pages 201-201
The Innovations in Science and Technology as a Demand for Bio-better Medicines in Europe....Pages 203-208
The Safety of Biological Medicines for Rheumatoid Arthritis....Pages 209-210
The Fractal Analysis as a Complementary Approach to Predict the Stability of Drug Delivery nano Systems (DDnSs) in Aqueous and Biological Media: A Regulatory Proposal or a Dream?....Pages 211-212
Nanothermodynamics Mediates Drug Delivery....Pages 213-220
The Neurodegenerative Potential of Chronic Stress: A Link Between Depression and Alzheimer’s Disease....Pages 221-222
Back Matter....Pages 223-224
