This standard-setting textbook has defined the field of immunology since 1984, and is now in its seventh edition continuing to deliver the detailed, authoritative and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Read more...
Section one : Introduction to immunology. The immune system / William E. Paul --
History of immunology / Steven Greenberg --
Section two : Organization and evolution of the immune system. Lymphoid tissues and organs / Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. Ruddle --
Evolution of the immune system / Martin F. Flajnik --
Section three : Immunoglobulins and B lymphocytes. Immunoglobins : structure and function / Harry W. Schroeder --
Immunoglobulins : molecular genetics / Edward E. Max and Sebastian Fugmann --
Antigen-antibody reactions / Jay A. Berzofsky and Ira Berkower --
B lymphocyte development / Richard R. Hardy --
B lymphocyte receptors, signaling mechanisms, and activation / Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. Pierce --
B lymphocyte responses / Michael McHeyzer-Williams --
Section four : T lymphocytes. T lymphocyte receptors / Mark M. Davis --
T lymphocyte signaling mechanisms / Takashi Saito --
T lymphocyte developmental biology / Ellen V. Rothenberg and Ameya Champhekar --
Peripheral T lymphocyte responses and function / Marc K. Jenkins --
Section five : The intersection of innate and adaptive immunity. The innate immune system / Luke A. J. O'Neill --
Dendritic cells / Michel C. Nussenzweig --
Natural killer cells / Wayne M. Yokoyama --
CD1d-restricted NKT cells / Albert S. Bendelac --
Macrophages and phagocytosis / Siamon Gordon --
Granulocytes and mast cells / Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. Cassatella --
The major histocompatibility complex and its proteins / David H. Margulies --
Antigen processing and presentation / Ted H. Hansen and Paul A. Roche --
Section six : Induction, regulation, and effector functions of the immune response. Immunogenicity and antigen structure / Jay A. Berzofsky --
Fc receptors and their role in immune regulation and inflammation / Jeffrey V. Ravetch and Falk Nimmerjahn --
Type I cytokines and interferons / Warren J. Leonard --
Interleukin-1 family cytokines / Charles A. Dinarello and Mihai G. Netea --
TNF-related cytokines in immunity / Carl F. Ware --
Chemokines / Philip M. Murphy --
Helper T cell differentiation and plasticity / John J. O'Shea --
Programmed cell death / Andrew L. Snow and Michael J. Lenardo --
Immunological memory / Shane Crotty, Susan M. Kaech, and Stephen P. Schoenberger --
Immunological tolerance / Pamela S. Ohashi --
Regulatory/Suppressor T cells / Ethan M. Shevach --
Mucosal immunity and microbiome / Yasmine Belkaid --
Neurophysiological reflex mechanisms in immunology / Chavan and Kevin J. Tracey --
Complement / B. Paul Morgan --
Cell-mediated cytotoxicity / Judy Lieberman --
Section seven : Immunity to infectious agents. The immune response to parasites / Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley --
Immunity to viruses / Hildegund C.J. Ertl --
Immunity to intracellular bacteria / Anca Dorhoi, Stephen T. Reece, and Stefan H. E. Kaufmann --
Immunity to extracellular bacteria / Moon H. Nahm and Jannet Katz --
Immunology of HIV infection / Bruce Walker --
Vaccines / Ennio De Gregorio, Ugo D'Oro, Sylvie Bertholet, and Rino Rappuoli --
Section 8 : Immunologic mechanisms in disease. Organ-specific autoimmunity / Ken T. Coppieters, Matthias G. von Herrath, and Dirk Homann --
Allergy / Marsha Wills-Karp --
Transplantation immunology / Megan Sykes --
Cancer immunology / Hans Schreiber --
Inborn errors of immunity / Jean-Laurent Casanova, Mary Ellen Conley, and Luigi D. Notarangelo.
