Fixing Your Damaged and Incorrect Genes is a book about a well-established biological process called DNA REPAIR. The book describes the multiple and varied biochemical strategies by which damaged or incorrect nucleotides are removed from DNA or are corrected. The book includes multiple figures of notable past and present scientists in the field. The book is uniquely focused on an audience of non-biologists and is written in simple language with minimal use of technical terms. It contains an extensive glossary that provides explanations of key words that readers are encouraged to refer to as they read. Fixing Your Damaged and Incorrect Genes is unique, there being no previously published books for non-biologists on the topic of DNA repair.
Readership: Interested lay readers and students at high school who are learning about biology in general.
Author(s): Errol C. Friedberg
Publisher: World Scientific
Year: 2019
Language: English
Pages: x+144
Tags: DNA repair;DNA Repair
Intro
Contents
Acknowledgements
About the Author
Chapter 1 Introduction
Chapter 2 The Early History of the DNA Repair Field
Chapter 3 The Composition and Structure of DNA
Chapter 4 The Era of Radiation Biology
Chapter 5 The Discovery of DNA Repair: Enzymatic Photoreactivation
Chapter 6 The Emergence of DNA Repair
Chapter 7 Excision Repair of DNA
Nucleotide Excision Repair (NER)
Transcription-Coupled Nucleotide Excision Repair (TCNER)
Base Excision Repair (BER)
Chapter 8 Recombinational DNA Repair
Chapter 9 Mismatch Repair
Chapter 10 The Adaptive and SOS Responses The Adaptive Response to Alkylation DamageThe SOS Response to DNA Damage
Chapter 11 DNA Repair in the Context of Chromatin
Chapter 12 Hereditary Diseases Associated with Defective Responses to DNA Damage
Xeroderma Pigmentosum (XP)
Ataxia Telangiectasia (AT)
Hereditary Non-Polyposis Colon Cancer (HNPCC) also called Lynch Syndrome
Bloom's Syndrome
Fanconi Anemia
Chapter 13 Conclusion
Glossary
Index
