Fishman's Pulmonary Diseases and Disorders, 2-Volume Set

Cover
Title Page
Copyright Page
Dedication
Contents
Contributors
Preface
PART 1: Perspectives
1 Milestones in the History of Pulmonary Medicine
PART 2: Scientific Basis of Lung Function in Health and Disease
SECTION 1 Genetic, Cellular, and Structural Basis of Normal Lung Function
2 Functional Design of the Human Lung for Gas Exchange
3 The Respiratory Muscles
4 Molecular Regulation of Lung Development
5 Pulmonary Surfactant and Disorders of Surfactant Homeostasis
6 Mucociliary Clearance
7 The Genetic Basis of Respiratory Disorders
8 Stem Cells and Respiratory Disease: Prospects for the Future
9 Personalized Pulmonary Medicine
SECTION 2 Physiological Principles of Normal Lung Function
10 Pulmonary Mechanics
11 Control of Ventilation
12 Sleep and Circadian Rhythms
13 The Pulmonary Circulation
14 Ventilation, Pulmonary Blood Flow, and Ventilation–Perfusion Relationships
15 Blood Gas Transport
16 Diffusion, Chemical Reactions, and Diffusing Capacity
17 Acid–Base Balance
18 Aging of the Respiratory System
SECTION 3 Lung Immunology
19 Innate and Adaptive Immunity in the Lung
20 Macrophages and Lymphocytes in the Lung
21 Mast Cells and Eosinophils
22 Antibody-Mediated Lung Defenses and Humoral Immunodeficiency
SECTION 4 Lung Injury and Repair
23 T Cell Responses in the Lung
24 Chemokines, Adipokines, and Growth Factors in the Lung
25 Redox Signaling and Oxidative Stress in Lung Diseases
26 Fibroblasts in Lung Homeostasis and Disease
PART 3: Symptoms and Signs of Respiratory Disease
SECTION 5 Clinical Approach to the Patient
27 Approach to the Patient with Respiratory Symptoms
SECTION 6 Diagnostic Procedures
28 Modern Approach to Thoracic Imaging Diagnosis
29 Thoracic Ultrasonography
30 Physiologic and Metabolic Assessment of Pulmonary Disorders Using Conventional Imaging Techniques and Positron Emission Tomography
31 Pulmonary Function Testing
32 Principles and Application of Cardiopulmonary Exercise Testing
33 Diagnostic Bronchoscopy, Transthoracic Needle Biopsy, and Related Procedures
34 Interventional Pulmonology
35 Diagnostic Thoracic Surgical Procedures: Thoracoscopy, VATS, RATS, and Thoracotomy
36 Evaluation of Respiratory Impairment and Disability
PART 4: Obstructive Lung Diseases
SECTION 7 Chronic Obstructive Pulmonary Disease
37 Pathology of Chronic Obstructive Pulmonary Disease: Diagnostic Features and Differential Diagnosis
38 Chronic Obstructive Pulmonary Disease: Epidemiology, Pathophysiology, Pathogenesis
39 Chronic Obstructive Pulmonary Disease and ?1-Antitrypsin Deficiency
40 Course and Treatment of Chronic Obstructive Pulmonary Disease
41 Cigarette Smoking, Smoking Cessation, and Electronic Cigarettes
42 Rehabilitation in Chronic Obstructive Pulmonary Disease and Other Respiratory Disorders
SECTION 8 Asthma
43 The Biology of Asthma
44 The Epidemiology of Asthma
45 Asthma: Clinical Presentation and Management
46 Allergic Bronchopulmonary Aspergillosis (Mycosis) and Severe Asthma with Fungal Sensitivity
SECTION 9 Other Obstructive Disorders
47 Upper Airway Obstruction in Adults
48 Cystic Fibrosis
49 Bronchiolitis
50 Bullous Lung Disease
51 Bronchiectasis
PART 5: Interstitial and Inflammatory Lung Diseases
52 Interstitial Lung Disease: A Clinical Overview and General Approach
53 Systemic Sarcoidosis
54 Idiopathic Pulmonary Fibrosis
55 Idiopathic Interstitial Pneumonias Other Than Idiopathic Pulmonary Fibrosis
56 Hypersensitivity Pneumonitis
57 Radiation Pneumonitis
58 Pulmonary Manifestations of the Collagen Vascular Diseases
59 Pulmonary Langerhans Cell Histiocytosis
60 Pulmonary Lymphangioleiomyomatosis
61 Diffuse Cystic Lung Diseases
62 Benign Metastasizing Leiomyoma
63 Depositional Lung Disorders: Amyloidosis, Pulmonary Calcification, and Pulmonary Ossification
PART 6: Drug-Induced Lung Diseases
64 Pulmonary Toxicity Related to Systemic Treatments for Cancer
65 Drug-induced Pulmonary Disease Due to Nonchemotherapeutic Agents
66 Lung Injury Associated with Recreational Drug Use
PART 7: Other Infiltrative and Airspace Disorders
67 The Lungs in Patients with Inborn Errors of Metabolism
68 Alveolar Hemorrhage Syndromes
69 Aspiration-Related Pulmonary Disorders
70 Pulmonary Alveolar Proteinosis Syndrome
71 Eosinophilic Lung Diseases
72 Pulmonary Arterial Hypertension
PART 8: Disorders of the Pulmonary Circulation
73 Pulmonary Thromboembolic Disease
74 Pulmonary Vasculitis
75 Pulmonary Arteriovenous Malformations
PART 9: Disorders of the Pleural Space
76 Nonmalignant Pleural Effusions
77 Malignant Pleural Effusions
78 Malignant Mesothelioma and Other Primary Pleural Tumors
79 Pneumothorax
PART 10: Diseases of the Mediastinum
80 Nonneoplastic Disorders of the Mediastinum
81 Congenital Cysts of the Mediastinum: Bronchopulmonary Foregut Anomalies
82 Primary Benign and Malignant Neoplasms of the Mediastinum
PART 11: Disorders of the Chest Wall, Diaphragm, and Spine
83 Nonmuscular Diseases of the Chest Wall
84 Effects of Neuromuscular Diseases on Ventilation
PART 12: Occupational and Environmental Disorders
SECTION 10 Occupational Disorders
85 Asbestos-Related Lung Disease
86 Chronic Beryllium Disease and Hard-Metal Lung Diseases
87 Coal Workers’ Lung Diseases and Silicosis
88 Occupational Asthma, Byssinosis, and Industrial Bronchitis
SECTION 11 Environmental Disorders
89 Indoor and Outdoor Air Pollution
90 Acute and Chronic Responses to Toxic Inhalations
91 High-Altitude Physiology and Clinical Disorders
92 Diving Physiology and Dysbarism
93 Thermal Lung Injury and Acute Smoke Inhalation
PART 13: Pulmonary Complications of Nonpulmonary Disorders
94 Noninfectious Pulmonary Complications of Hematopoietic Stem Cell and Solid Organ Transplantation
95 Pulmonary Complications of Sickle Cell Disease
96 Pulmonary Disorders and Pregnancy
97 Pulmonary Complications of Intra-abdominal Disease
PART 14: Sleep and Sleep Disorders
98 Sleep Apnea Syndromes: Central and Obstructive
99 Sleep-related Hypoventilation Syndromes
100 Changes in the Cardiorespiratory System During Sleep
101 Differential Diagnosis and Evaluation of Sleepiness
PART 15: Surgical Aspects of Pulmonary Medicine
102 Perioperative Respiratory Considerations in the Surgical Patient
103 Acute Respiratory Failure in the Surgical Patient
104 Thoracic Trauma
105 Developmental Disorders of the Lung
106 Lung Transplantation
PART 16: Cancer and Other Malignancies of the Lungs
107 Genetic and Molecular Changes in Lung Cancer: Prospects for a Personalized Pharmacologic Approach to Treatment
108 Epidemiology of Lung Cancer
109 Lung Cancer Screening
110 Approach to the Patient with Pulmonary Nodules
111 The Pathology of Bronchogenic Carcinoma
112 Clinical Evaluation, Diagnosis, and Staging of Lung Cancer
113 Treatment of Non–Small-Cell Lung Cancer: Surgery
114 Treatment of Non–Small-Cell Lung Cancer: Chemotherapy and Immunotherapy
115 Treatment of Non–Small-Cell Lung Cancer: Radiation Therapy
116 Small Cell Lung Cancer: Diagnosis, Treatment, and Natural History
117 Uncommon Tumors of the Lung
118 Extrapulmonary Syndromes Associated with Lung Tumors
119 Lymphoproliferative Diseases Involving the Lung
PART 17: Infectious Diseases of the Lungs
SECTION 12 General Concepts
120 Pulmonary Clearance of Infectious Agents
121 The Lung Microbiome
122 Approach to Pulmonary Infection in the Immunocompetent Host
123 Approach to Pulmonary Infection in the Immunocompromised Host
124 Microbial Virulence Factors in Pulmonary Infections
125 Principles of Antibiotic Use and the Selection of Empiric Therapy for Pneumonia
SECTION 13 Common Syndromes in Pulmonary Infectious Diseases
126 Viral Infections of the Lung and Respiratory Tract
127 Aspiration, Empyema, Lung Abscesses, and Anaerobic Infections
128 Acute Bronchitis and Community-Acquired Pneumonia
129 Nosocomial Pneumonia, Including Ventilator-associated Pneumonia
SECTION 14 Major Pathogens in Pulmonary Infections
130 Tuberculosis
131 Pulmonary Diseases Due to Nontuberculous Mycobacteria
132 Aspergillus, Candida, and Other Opportunistic Pulmonary Mycoses
133 Cryptococcosis and the Endemic Mycoses: Histoplasma, Blastomyces, and Coccidioides
134 Pneumocystis Pneumonia
135 Protozoan Infections of the Thorax
136 Helminthic Diseases of the Lung
137 Nocardiosis and Actinomycosis
138 Zoonotic and Environmental Bacterial Pneumonias
PART 18: Respiratory Failure
139 Respiratory Failure: An Overview
SECTION 15 Lung Failure
140 Acute Respiratory Distress Syndrome: Pathogenesis
141 Acute Respiratory Distress Syndrome: Clinical Features, Management, and Outcomes
SECTION 16 Respiratory Pump Failure
142 Chronic Hypercapnic Respiratory Failure: Pathogenesis and Management
SECTION 17 Management and Therapeutic Interventions
143 Oxygen Therapy and Toxicity
144 Pulmonary Pharmacotherapy
145 Intubation and Upper Airway Management
146 Hemodynamic and Respiratory Monitoring in Acute Respiratory Failure
147 Principles of Mechanical Ventilation
148 Principles of Noninvasive Pressure-targeted Ventilation
149 Extracorporeal Membrane Oxygenation (ECMO) in Acute Respiratory Failure
150 Nutrition in Pulmonary Disease
151 Diagnosis and Treatment of Pain, Agitation, and Delirium in the Intensive Care Unit
152 Ethics and Palliative Care in Critical Care Units
APPENDIXES
Appendix A Terms and Symbols in Respiratory Physiology
Appendix B Normal Values for a Healthy 20-Year Old Seated Man
Index