Fifty Years of Magnetoencephalography celebrates the first half century of research in and clinical applications of magnetoencephalography (MEG). It catalogs and documents its evolution as a means of imaging the ongoing activity of the brain and the activation of particular neuronal networks within it that mediate sensory motor and higher functions like language. The volume's first section looks at the discovery of MEG and its first tentative applications by three of its founders. The following sections detail the rapid progress in the development of the instrumentation necessary for recording noninvasively the magnetic signals on the head that are associated with the brain activity; improvements in the techniques for analyzing the magnetic signals and reconstructing, on their basis, the functional images of brain activity; and improvements in our understanding of the nature and significance of those signals. Subsequent sections of the book detail the main clinical applications of MEG in localizing brain areas that contain sources of epileptiform activity and areas encompassing parts of functional networks essential for motor and sensory function as well as for language that have become an essential part of planning for brain surgery in many epilepsy and tumor surgery centers around the world. In addition, several chapters describe the most current efforts aiming at expanding the utility of MEG in clinical diagnosis and theoretical research.
Author(s): Andrew C. Papanicolaou, Timothy P.L. Roberts, James W. Wheless
Publisher: Oxford University Press
Year: 2020
Language: English
Pages: 444
City: New York
Cover
Fifty Years of Magnetoencephalography
Copyright
Contents
Preface
About the Editors
Contributors
Section I. The Beginnings
1. The First Magnetoencephalography Report: 1968
2. The Beginning of Biomagnetism and Magnetoencephalography Research in Finland in the 1970s
3. A View From the Beginning of Magnetoencephalography: After Half a Century
Section II. Technical Advances
4. Physiological Bases of Magnetoencephalography and Electroencephalography
5. Which Part of the Neuronal Current Can Be Determined by Electroencephalography?
6. Magnetoencephalography Source Estimation: Transforming the Sensor-Level Signals to Estimates of Brain Activity
7. The Need for and Road to Hybrid Magnetoencephalography–Magnetic Resonance Imaging
8. Magnetoencephalography Using Optically Pumped Magnetometers
Section III. Applications to Epilepsy
9. Guidelines and Practical Considerations for Mapping Epileptiform Activity and Network Connectivity With Magnetoencephalography
10. Beyond the Irritative Zone: Use of Magnetoencephalography to Characterize Aspects of the Epileptogenic Zone
11. Use of Multiple Frequency Bands in Magnetoencephalography for Characterization of Epilepsy
12. Can Magnetoencephalography Identify the Epileptogenic Pathology in Children?
13. Revisional Analysis of Electroencephalography and Magnetoencephalography Based on Comprehensive Epilepsy Conference
14. Epileptic Slow Wave Activity
Section IV. Somatosensory, Motor, and Language Mapping
15. Clinical Motor Mapping With Magnetoencephalography: Historical Approaches, Challenges, and Recommendations for Best Practice
16. Investigations of the Somatosensory System With Magnetoencephalography: From Research to Clinical Applications
17. Language Mapping With Magnetoencephalography: Clinical and Research Applications
Section V. Exploring the Brain Mechanisms of Cognition
18. Reading, Reading Acquisition, and Reading Disability (Dyslexia)
19. Decoding Cognitive Function With Magnetoencephalography
20. How Brain Rhythms Reflect Cognitive Processes
Section VI. Neuronal Correlates of Cognitive and Affective Disorders
21. Applications of Magnetoencephalography to Autism Spectrum Disorder
22. Functional Wounds of an Invisible Injury: Visualizing Cognition in Post-traumatic Stress Disorder
23. Identifying Neural Abnormalities in Schizophrenia
24. Biomarkers in Pediatric Magnetoencephalography
25. Magnetoencephalography in Alzheimer Disease: Correlation With Current Biomarkers
Postscript: Fifty Years of Magnetoencephalography— An “Interim” Epilogue
Index
