This series, established by Victor Gold in 1963, brings before the chemical community substantial, authoritative, and considered reviews of areas of chemistry in which quantitative methods are used in the study of the structures of organic compounds and their relation to physical and chemical properties. Physical organic chemistry is viewed as a particular approach to scientific enquiry rather than a further intellectual specialization. Organometallic compounds are included, and relevant aspects of physical theoretical, inorganic, and biological chemistry are incorporated in reviews where appr. Read more... Content: Front Cover; Advances in Physical Organic Chemistry, Volume 25; Copyright Page; Contents; Preface; Contributors to Volume 25; Chapter 1. Static and Dynamic Stereochemistry of Alkyl and Analogous Groups; Chapter 2. Mechanism and Catalysis of Nucleophilic Substitution in Phosphate Esters; Chapter 3. Perchloro-organic Chemistry: Structure, Spectroscopy and Reaction Pathways; Author Index; Cumulative Index of Authors; Cumulative Index of Titles. Abstract: This series, established by Victor Gold in 1963, brings before the chemical community substantial, authoritative, and considered reviews of areas of chemistry in which quantitative methods are used in the study of the structures of organic compounds and their relation to physical and chemical properties. Physical organic chemistry is viewed as a particular approach to scientific enquiry rather than a further intellectual specialization. Organometallic compounds are included, and relevant aspects of physical theoretical, inorganic, and biological chemistry are incorporated in reviews where appr