A comprehensive collection of the most recent knowledge on the biological bases of various kinds of epilepsies and modern clinical approaches to their treatment. Epilepsy affects about 0.5-1% of the world's population (about 50,000,000 individuals) and the main goal of its treatment is to eliminate seizures without creating side effects. Despite numerous advances in the treatment of epilepsy and the approval of several new antiepileptic drugs, about 30% of patients continue to experience recurrent seizures which are medically, physically, and/or socially disabling. The editor of this volume hopes that by bridging the gap between the fundamental biology of epilepsy and its clinical implications he might spur further research and treatment options.
Author(s): Pasquale Striano (eds.)
Series: Contemporary Clinical Neuroscience
Edition: 1
Publisher: Springer International Publishing
Year: 2015
Language: English
Pages: 238
Tags: Neurosciences; Neurosciences; Psychiatry; Neurology; Clinical Psychology
Front Matter....Pages i-x
Copy Number Variants and Epilepsy: New Emerging Syndromes....Pages 1-14
Mutations of Ion Channels in Genetic Epilepsies....Pages 15-34
LGI1 Dysfunction in Inherited and Acquired Epileptic Disorders....Pages 35-45
Glioneuronal Tumors and Epilepsy: Clinico-Diagnostic Features and Surgical Strategies....Pages 47-70
Metabolic Causes of Epilepsy....Pages 71-99
New Insights into Mechanisms Underlying Generalized Reflex Seizures....Pages 101-107
Current Status and Future Prospective of Neuroimaging for Epilepsy....Pages 109-137
The Complex Relationship Between Epilepsy and Headache and the Concept of Ictal Epileptic Headache....Pages 139-162
Epilepsy and Immune System: A Tour Around the Current Literature....Pages 163-182
Novel Molecular Targets for Drug-Treatment of Epilepsy....Pages 183-199
Reproductive Hormones in Epilepsy Therapy: From Old Promises to New Hopes....Pages 201-211
Neuromodulation for the Treatment of Drug-Resistant Epilepsy....Pages 213-230
New Radiosurgical Paradigms to Treat Epilepsy Using Synchrotron Radiation....Pages 231-236
Back Matter....Pages 237-238
