Genes interact with environment, experience, and the biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity. * Explores latest topics in neural circuits and behavior research in zebrafish, drosophila, c.elegans, and mouse models* Includes methods for testing with ethical, legal, and social implications* Critically analyzes prospects future prospects
Author(s): Zdenko Herceg and Toshikazu Ushijima (Eds.)
Series: Advances in Genetics 70
Edition: 1
Publisher: Academic Press
Year: 2010
Language: English
Pages: 2-396
Tags: Биологические дисциплины;Генетика;Эпигенетика;
Content:
Series Editors
Page ii
Copyright
Page iv
Contributors
Pages xi-xii
Preface
Pages xiii-xiv
Zdenko Herceg, Toshikazu Ushijima
1 - Introduction: Epigenetics and Cancer
Pages 1-23
Zdenko Herceg, Toshikazu Ushijima
2 - DNA Methylation and Cancer
Pages 27-56
Marta Kulis, Manel Esteller
3 - Histone Modifications and Cancer
Pages 57-85
Carla Sawan, Zdenko Herceg
4 - Epigenetics and miRNAs in Human Cancer
Pages 87-99
Muller Fabbri, George A. Calin
5 - Interplay Between Different Epigenetic Modifications and Mechanisms
Pages 101-141
Rabih Murr
6 - Genomic Imprinting Syndromes and Cancer
Pages 145-175
Derek Hock Kiat Lim, Eamonn Richard Maher
7 - Epigenetic Codes in Stem Cells and Cancer Stem Cells
Pages 177-199
Yasuhiro Yamada, Akira Watanabe
8 - Inheritance of Epigenetic Aberrations (Constitutional Epimutations) in Cancer Susceptibility
Pages 201-243
Megan P. Hitchins
9 - Cancer Epigenome
Pages 247-276
Matthias Lechner, Chris Boshoff, Stephan Beck
10 - Identification of Driver and Passenger DNA Methylation in Cancer by Epigenomic Analysis
Pages 277-308
Satish Kalari, Gerd P. Pfeifer
11 - Epigenetic Drivers of Genetic Alterations
Pages 309-323
Minoru Toyota, Hiromu Suzuki
12 - DNA Demethylating Agents and Epigenetic Therapy of Cancer
Pages 327-340
Samson Mani, Zdenko Herceg
13 - Histone Modification Therapy of Cancer
Pages 341-386
Chiara Biancotto, Gianmaria Frigè, Saverio Minucci
Index
Pages 387-396
