Epidemiology and Biostatistics: An Introduction to Clinical Research

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This text provides students and other health professionals with the knowledge necessary to interpret clinical research articles, design clinical studies, and learn essential epidemiological concepts in an expedient and concise manner. Fundamental concepts are presented in a highly succinct format suitable for students with no previous background in epidemiology or statistics.

Drawing on teaching experience and student feedback, the author has created a text that attempts to recreate the perspective of learning epidemiology and biostatistics for the first time. The text serves as a rapid, intensive course in clinical research methods that can be used by students taking the required epidemiology course, residency and fellowship programs for physicians entering the clinical research portion of their training, and clinical research programs in fields such as nursing and nutrition that need an intensive course in clinical research design.

Author(s): Bryan Kestenbaum (auth.)
Edition: 1
Publisher: Springer-Verlag New York
Year: 2009

Language: English
Pages: 242
Tags: Epidemiology; Statistics for Life Sciences, Medicine, Health Sciences; Medicine/Public Health, general; Health Promotion and Disease Prevention

Front Matter....Pages i-xiii
Front Matter....Pages 1-1
Measures of Disease Frequency....Pages 3-12
General Considerations in Clinical Research Design....Pages 13-24
Case Reports and Case Series....Pages 25-27
Cross-Sectional Studies....Pages 29-31
Cohort Studies....Pages 33-44
Case-Control Studies....Pages 45-57
Randomized Trials....Pages 59-73
Misclassification....Pages 75-89
Introduction to Confounding....Pages 91-100
Methods to Control for Confounding....Pages 101-111
Effect Modification....Pages 113-120
Screening....Pages 121-138
Diagnostic Testing....Pages 139-150
Front Matter....Pages 152-152
Summary Measures in Statisitics....Pages 153-162
Introduction to Statistical Inference....Pages 163-170
Hypothesis Testing....Pages 171-180
Interpreting Hypothesis Tests....Pages 181-187
Linear Regression....Pages 189-207
Non-Linear Regression....Pages 209-214
Survival Analysis....Pages 215-228
Back Matter....Pages 229-242