This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis.
Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field.
All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach.
A must for all chemists and biotechnologists.
Language: English
Pages: 2008
Tags: Химия и химическая промышленность;Кинетика и катализ;
Content:
Chapter 1 Introduction – Principles and Historical Landmarks of Enzyme Catalysis in Organic Synthesis (pages 1–42): Prof. Dr. Harald Groger and Yasuhisa Asano
Chapter 2 Concepts in Biocatalysis (pages 43–66): Eduardo Garcia?Urdiales, Ivan Lavandera and Vicente Gotor
Chapter 3 Discovery of Enzymes (pages 67–87): Wolfgang Aehle and Juergen Eck
Chapter 4 Rational Design of Enzymes (pages 89–117): Jurgen Pleiss
Chapter 5 Directed Evolution of Enzymes (pages 119–190): Manfred T. Reetz
Chapter 6 Production and Isolation of Enzymes (pages 191–215): Yoshihiko Hirose
Chapter 7 Reaction and Process Engineering (pages 217–247): John M. Woodley
Chapter 8 Hydrolysis and Formation of Carboxylic Acid Esters (pages 249–362): Monica Paravidino, Philipp Bohm, Prof. Dr. Harald Groger and Ulf Hanefeld
Chapter 9 Hydrolysis and Formation of Epoxides (pages 363–416): Jeffrey H. Lutje Spelberg and Erik J. de Vries
Chapter 10 Hydrolysis and Formation of Glycosidic Bonds (pages 417–466): Daniela Monti and Sergio Riva
Chapter 11 Addition of Water to C?C Bonds and its Elimination (pages 467–501): Jianfeng Jin, Isabel W. C. E. Arends and Ulf Hanefeld
Chapter 12 Industrial Application and Processes Forming C?O Bonds (pages 503–530): Lutz Hilterhaus and Andreas Liese
Chapter 13 Hydrolysis of Nitriles to Amides (pages 531–544): Alexander Yanenko and Steffen Osswald
Chapter 14 Hydrolysis of Nitriles to Carboxylic Acids (pages 545–559): Steffen O?wald and Alexander Yanenko
Chapter 15 Hydrolysis of Amides (pages 561–650): Theo Sonke and Bernard Kaptein
Chapter 16 Hydrolysis and Formation of Hydantoins (pages 651–674): Jun Ogawa, Nobuyuki Horinouchi and Sakayu Shimizu
Chapter 17 Hydrolysis and Synthesis of Peptides (pages 675–748): Timo Nuijens, Peter J. L. M. Quaedflieg and Hans?Dieter Jakubke
Chapter 18 C?N Lyases Catalyzing Addition of Ammonia, Amines, and Amides to C?C and C?O Bonds (pages 749–778): Bian Wu, Wiktor Szymanski, Ciprian G. Crismaru, Ben L. Feringa and Dick B. Janssen
Chapter 19 Application of Transaminases (pages 779–820): Matthias Hohne and Uwe T. Bornscheuer
Chapter 20 Industrial Applications and Processes Using Enzymes Acting on C?N Bonds (pages 821–853): Ruslan Yuryev, Lutz Hilterhaus and Andreas Liese
Chapter 21 Aldol Reactions (pages 855–917): Wolf?Dieter Fessner
Chapter 22 Acyloin and Benzoin Condensations (pages 919–945): Martina Pohl, Carola Dresen, Maryam Beigi and Michael Muller
Chapter 23 Cleavage and Formation of Cyanohydrins (pages 947–990): Mandana Gruber?Khadjawi, Martin H. Fechter and Herfried Griengl
Chapter 24 Industrial Application and Processes Using Carbon?Carbon Lyases (pages 991–1000): Lutz Hilterhaus and Andreas Liese
Chapter 25 Hydrolysis and Formation of P?O Bonds (pages 1001–1033): Ron Wever and Teunie van Herk
Chapter 26 Reduction of Ketones and Aldehydes to Alcohols (pages 1035–1110): Prof. Dr. Harald Groger, Werner Hummel, Sonja Borchert and Marina Krau?er
Chapter 27 Reduction of C?C Double Bonds (pages 1111–1163): Despina J. Bougioukou and Jon D. Stewart
Chapter 28 Reductive Amination of Keto Acids (pages 1165–1203): Werner Hummel and Prof. Dr. Harald Groger
Chapter 29 Industrial Application of Oxidoreductase Catalyzed Reduction of Ketones and Aldehydes (pages 1205–1223): Katharina Gotz, Lutz Hilterhaus and Andreas Liese
Chapter 30 Oxyfunctionalization of C?H Bonds (pages 1225–1267): Vlada B. Urlacher and Marco Girhard
Chapter 31 Oxyfunctionalization of C?C Multiple Bonds (pages 1269–1324): Bruno Buhler, Katja Buhler and Frank Hollmann
Chapter 32 Oxidation of Alcohols, Aldehydes, and Acids (pages 1325–1437): Frank Hollmann, Katja Buhler and Bruno Buhler
Chapter 33 Baeyer–Villiger Oxidations (pages 1439–1485): Marko D. Mihovilovic
Chapter 34 Aromatic Oxidations (pages 1487–1533): David J. Leak, Ying Yin, Jun?Jie Zhang and Ning?Yi Zhou
Chapter 35 Oxidation of C?N Bonds (pages 1535–1552): Nicholas J. Turner
Chapter 36 Oxidation at Sulfur and Oxidation of Amino Groups (pages 1553–1567): Anke Matura and Karl?Heinz van Pee
Chapter 37 Halogenation (pages 1569–1584): Karl?Heinz van Pee
Chapter 38 Industrial Application and Processes Using Biocatalysts for Oxidation Reactions (pages 1585–1606): Lutz Hilterhaus and Andreas Liese
Chapter 39 Isomerizations (pages 1607–1684): Yasuhisa Asano and Kathrin Holsch
Chapter 40 Industrial Application and Processes Using Isomerases (pages 1685–1691): Lutz Hilterhaus and Andreas Liese
Chapter 41 Enzymatic Catalytic Promiscuity and the Design of New Enzyme Catalyzed Reactions (pages 1693–1733): Uwe T. Bornscheuer and Romas J. Kazlauskas
Chapter 42 Catalytic Antibodies (pages 1735–1776): Ivan V. Smirnov, Alexey A. Belogurov, Arina V. Kozyr and Alexander Gabibov
Chapter 43 Chemoenzymatic Dynamic Kinetic Resolution and Related Dynamic Asymmetric Transformations (pages 1777–1806): Ibrar Hussain and Jan?E. Backvall
Chapter 44 Biocatalysis in Material Science (pages 1807–1835): Georg M. Guebitz
Chapter 45 Industrial Applications of Enzymes in Emerging Areas (pages 1837–1846): Anne van den Wittenboer, Lutz Hilterhaus and Andreas Liese
Chapter 46 Tabular Survey of Available Enzymes (pages 1847–1938): David Rozzell