Encyclopedia of Cancer, Four-Volume Set, Vosl. 1-4, 2nd Edition

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Since the publication of the first edition of the Encyclopedia of Cancer, an amazing amount of new information has been disseminated in the field of cancer research. This second edition strives to capture the advances occurring in the etiology, prevention, and treatment of cancer, from basic science to clinical application. By providing concise expositions on a broad range of topics, the Encyclopedia is an excellent resource for those seeking information beyond their specific areas of expertise. Written by a distinguished panel of authors, entries cover a variety of aspects of cancer such as oncology, immunology, epidemiology, gene therapy, oncogenes/tumor suppressor genes, and pharmacology. This outstanding reference is essential for anyone involved in the study or treatment of cancer. An online version of the Encyclopedia of Cancer is available on ScienceDirect. Visit http://info.sciencedirect.com/reference_works/ for contact and subscription information. Access options are available even if you're not an existing ScienceDirect customer! Key Features* Covers all aspects of cancer, segueing from basic science to clinical topics* Includes an additional volume to incorporate all the new advances in the etiology, prevention, and treatment of cancer made since the first edition* Convenient organization employs standard entry format for quick and easy reference* Extensive cross-referencing provides reader with broader range of knowledge* Contributions solicited from among the top names in a variety of fields

Author(s): Joseph R. Bertino
Edition: 2
Publisher: Academic Press
Year: 2002

Language: English
Pages: 4316
Tags: Медицинские дисциплины;Онкология;Энциклопедии

Encyclopedia of Cancer.pdf......Page 1
Editorial Advisory Board, Page i.pdf......Page 2
Editor-in-Chief, Page i.pdf......Page 3
Foreword, Page xxxvii.pdf......Page 4
Anti-Vascular Endothelial Growth Factor-Based Angiostatics, Pages 135-141.pdf......Page 5
Integrin-Targeted angiostatics, Pages 501-509.pdf......Page 12
Vascular Targeting, Pages 501-507.pdf......Page 21
Anti-idiotypic Antibody Vaccines, Pages 79-87.pdf......Page 28
Antibody–Toxin and Growth Factor–Toxin Fusion Proteins, Pages 71-77.pdf......Page 37
Cancer Vaccines Gene Therapy and Dendritic Cell-Based Vaccines, Pages 319-325.pdf......Page 44
Cancer Vaccines Peptide- and Protein-Based Vaccines, Pages 327-336.pdf......Page 51
Carbohydrate-Based Vaccines, Pages 337-344.pdf......Page 61
Cell-Mediated Immunity to Cancer, Pages 415-424.pdf......Page 69
DNA Damage, DNA Repair, and Mutagenesis, Pages 79-87.pdf......Page 79
DNA-Based Cancer Vaccines, Pages 73-78.pdf......Page 88
Graft versus Leukemia and Graft versus Tumor Activity, Pages 325-338.pdf......Page 94
Interferons Cellular and Molecular Biology of Their Actions, Pages 511-521.pdf......Page 108
Interleukins, Pages 523-535.pdf......Page 119
Macrophages, Pages 77-88.pdf......Page 132
Monoclonal Antibodies Leukemia and Lymphoma, Pages 235-245.pdf......Page 144
Radiolabeled Antibodies, Overview, Pages 29-40.pdf......Page 155
Stem Cell Transplantation, Pages 253-263.pdf......Page 167
Targeted Toxins, Pages 297-306.pdf......Page 178
Ataxia Telangiectasia Syndrome, Pages 153-164.pdf......Page 188
Ewing's Sarcoma (Ewing's Family Tumors), Pages 197-207.pdf......Page 200
Gastric Cancer Inherited Predisposition, Pages 253-258.pdf......Page 211
Genetic Alterations in Brain Tumors, Pages 267-272.pdf......Page 217
Genetic Predisposition to Prostate Cancer, Pages 279-285.pdf......Page 223
Hereditary Risk of Breast and Ovarian Cancer BRCA1 and BRCA2.pdf......Page 230
Li–Fraumeni Syndrome, Pages 21-29.pdf......Page 235
Lung Cancer Molecular and Cellular Abnormalities, Pages 45-50.pdf......Page 244
Melanoma Cellular and Molecular Abnormalities, Pages 141-152.pdf......Page 250
Mismatch Repair Biochemistry and Genetics, Pages 179-185.pdf......Page 262
Carcinogen–DNA Adducts, Pages 345-357.pdf......Page 269
Carcinogenesis Role of Reactive Oxygen and Nitrogen Species, Pages 359-367.pdf......Page 282
Chemical Mutagenesis and Carcinogenesis, Pages 433-447.pdf......Page 291
Hormonal Carcinogenesis, Pages 41-428.pdf......Page 306
Multistage Carcinogenesis, Pages 275-285.pdf......Page 318
Tobacco Carcinogenesis, Pages 397-406.pdf......Page 329
Animal Models for Colon Cancer Chemoprevention, Pages 49-55.pdf......Page 339
Antioxidants Carcinogenic and Chemopreventive Properties, Pages 89-101.pdf......Page 346
Cancer Risk Reduction (DietSmoking CessationLifestyle Changes), Pages 311-317.pdf......Page 359
Chemoprevention Trials, Pages 457-472.pdf......Page 366
Chemoprevention, Pharmacology of, Pages 449-455.pdf......Page 382
Molecular Epidemiology and Cancer Risk, Pages 213-220.pdf......Page 389
Nutritional Supplements and Diet as Chemoprevention Agents, Pages 337-351.pdf......Page 397
Drug Resistance DNA Sequence Amplification, Pages 119-134.pdf......Page 412
Genetic Basis for Quantitative and Qualitative Changes in Drug Targets, Pages 273-277.pdf......Page 428
Hormone Resistance in Prostate Cancer, Pages 429-436.pdf......Page 433
Hypoxia and Drug Resistance, Pages 461-467.pdf......Page 441
Multidrug Resistance I P-Glycoprotein, Pages 247-254.pdf......Page 448
Multidrug Resistance II MRP and Related Proteins, Pages 255-267.pdf......Page 456
P-glycoprotein as a General Antiapoptotic Protein, Pages 433-441.pdf......Page 469
Resistance to Antibody Therapy, Pages 93-98.pdf......Page 478
Resistance to DNA-Damaging Agents, Pages 99-106.pdf......Page 484
Resistance to Inhibitor Compounds of Thymidylate Synthase, Pages 107-113.pdf......Page 492
Resistance to Inhibitors of Dihydrofolate Reductase, Pages 115-127.pdf......Page 499
Resistance to Topoisomerase-Targeting Agents, Pages 129-141.pdf......Page 512
Taxol and Other Molecules That Interact with Microtubules, Pages 319-327.pdf......Page 525
Vinca Alkaloids and Epipodophyllotoxins, Pages 509-512.pdf......Page 534
Alkylating Agents, Pages 35-42.pdf......Page 538
Anthracyclines, Pages 57-61.pdf......Page 546
Bleomycin, Pages 223-227.pdf......Page 551
Camptothecins, Pages 301-309.pdf......Page 556
Chemotherapy Synergism and Antagonism, Pages 473-484.pdf......Page 565
Cisplatin and Related Drugs, Pages 525-543.pdf......Page 577
Corticosteroids, Pages 23-31.pdf......Page 596
Estrogens and Antiestrogens, Pages 179-188.pdf......Page 605
Folate Antagonists, Pages 235-241.pdf......Page 615
L-Asparaginase, Pages 1-6.pdf......Page 622
Protein Kinase Inhibitors, Pages 475-480.pdf......Page 628
Purine Antimetabolites, Pages 515-525.pdf......Page 634
Pyrimidine Antimetabolites, Pages 527-534.pdf......Page 645
Bladder Cancer Epidemiology, Pages 215-221.pdf......Page 653
Brain and Central Nervous System Cancer, Pages 259-270.pdf......Page 660
Colorectal Cancer Molecular and Cellular Abnormalities, Pages 9-21.pdf......Page 672
Esophageal Cancer Risk Factors and Somatic Genetics, Pages 161-168.pdf......Page 685
Kidney, Epidemiology, Pages 543-552.pdf......Page 693
Liver Cancer Etiology and Prevention, Pages 39-44.pdf......Page 703
Lung, Larynx, Oral Cavity, and Pharynx, Pages 51-58.pdf......Page 709
Melanoma Biology, Pages 131-139.pdf......Page 717
Non-Hodgkin's Lymphoma and Multiple Myeloma Incidence and Risk Factors, Pages 329-336.pdf......Page 726
Ovarian Cancer Molecular and Cellular Abnormalities, Pages 361-368.pdf......Page 734
Pancreatic Cancer Cellular and Molecular Mechanisms, Pages 383-391.pdf......Page 742
Pediatric Cancers, Molecular Features, Pages 409-417.pdf......Page 751
Thyroid Cancer, Pages 387-392.pdf......Page 760
Adeno-Associated Virus A Vector for High-Efficiency Gene Transduction, Pages 25-33.pdf......Page 766
Antibodies in the Gene Therapy of Cancer, Pages 63-69.pdf......Page 775
Antisense Nucleic Acids Clinical Applications, Pages 119-125.pdf......Page 782
Antisense Medicinal Chemistry, Pages 103-117.pdf......Page 789
Antisense Progress toward Gene-Directed Cancer Therapy, Pages 127-134.pdf......Page 804
Cationic Lipid-Mediated Gene Therapy, Pages 375-381.pdf......Page 812
Cytokine Gene Therapy, Pages 33-40.pdf......Page 819
Gene Therapy Vectors Safety Considerations, Pages 259-265.pdf......Page 827
Liposome-Mediated Gene Therapy, Pages 31-37.pdf......Page 834
p53 Gene Therapy, Pages 425-432.pdf......Page 841
Replication-Selective Viruses for Cancer Treatment, Pages 71-91.pdf......Page 849
Retroviral Vectors, Pages 153-166.pdf......Page 870
Ribozymes and Their Applications, Pages 179-188.pdf......Page 884
Suicide Genes, Pages 285-296.pdf......Page 894
Targeted Vectors for Cancer Gene Therapy, Pages 307-318.pdf......Page 906
Transfer of Drug Resistance Genes to Hematopoietic Precursors, Pages 433-447.pdf......Page 918
All-1, Pages 43-48.pdf......Page 933
EWS-ETS Fusion Genes, Pages 209-213.pdf......Page 939
PAX3–FKHR and PAX7–FKHR Gene Fusions in Alveolar Rhabdomyosarcoma, Pages 403-408.pdf......Page 944
RUNX-CBF Transcription Factors, Pages 189-195.pdf......Page 950
TLS–CHOP in Myxoid Liposarcoma, Pages 393-396.pdf......Page 957
Brain Cancer and Magnetic Resonance Spectroscopy, Pages 271-277.pdf......Page 961
Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging, Introduction, Pages 89-103.pdf......Page 968
Magnetic Resonance Spectroscopy of Cancer Clinical Overview, Pages 105-114.pdf......Page 983
Metabolic Diagnosis of Prostate Cancer by Magnetic Resonance Spectroscopy, Pages 167-177.pdf......Page 993
PET Imaging and Cancer, Pages 419-424.pdf......Page 1004
Immune Deficiency Opportunistic Tumors, Pages 469-485.pdf......Page 1010
Molecular Basis for Tumor Immunity, Pages 197-212.pdf......Page 1027
T Cells against Tumors, Pages 329-337.pdf......Page 1043
T Cells and Their Effector Functions, Pages 339-351.pdf......Page 1052
Tumor Antigens, Pages 459-466.pdf......Page 1065
Tumor Cell Motility and Invasion, Pages 467-473.pdf......Page 1073
Vascular Targeting, Pages 501-507.pdf......Page 1080
Autocrine and Paracrine Growth Mechanisms in Cancer Progression and Metastasis, Pages 165-177.pdf......Page 1087
Molecular Mechanisms of Cancer Invasion, Pages 221-233.pdf......Page 1100
Bcl-2 Family Proteins and the Dysregulation of Programmed Cell Death, Pages 179-197.pdf......Page 1113
c-mos Protooncogene, Pages 545-553.pdf......Page 1132
ETS Family of Transcription Factors, Pages 189-196.pdf......Page 1141
fos Oncogene.pdf......Page 1149
myb, Pages 287-296.pdf......Page 1155
Ras Proteins, Pages 41-48.pdf......Page 1165
STAT Proteins in Growth Control, Pages 245-252.pdf......Page 1173
Steroid Hormones and Hormone Receptors, Pages 275-284.pdf......Page 1181
Wnt Signaling, Pages 553-559.pdf......Page 1191
Photodynamic Therapy Basic Principles and Applications to Skin Cancer, Pages 443-451.pdf......Page 1198
Photodynamic Therapy Clinical Applications, Pages 453-462.pdf......Page 1207
Brachytherapy, Pages 239-257.pdf......Page 1217
Dosimetry and Treatment Planning for Three-Dimensional Radiation Therapy, Pages 109-118.pdf......Page 1236
Hyperthermia, Pages 447-459.pdf......Page 1246
Late Effects of Radiation Therapy, Pages 7-19.pdf......Page 1259
Molecular Aspects of Radiation Biology, Pages 187-195.pdf......Page 1272
Proton Beam Radiation Therapy, Pages 481-490.pdf......Page 1281
Radiation Resistance, Pages 1-11.pdf......Page 1291
Radiobiology, Principles of, Pages 13-28.pdf......Page 1302
Stereotactic Radiosurgery of Intracranial Neoplasms, Pages 265-273.pdf......Page 1318
Total Body Irradiation, Pages 407-414.pdf......Page 1327
Melanoma Epidemiology, Pages 153-166.pdf......Page 1335
Multiple Myeloma, Pages 269-274.pdf......Page 1349
Neoplasms in Acquired Immunodeficiency Syndrome, Pages 297-302.pdf......Page 1355
Neoplasms of Unknown Primary Site, Pages 303-314.pdf......Page 1361
Neuroblastoma, Pages 315-321.pdf......Page 1373
Ovarian Cancer Diagnosis and Treatment, Pages 353-360.pdf......Page 1380
Pancreas and Periampullary Tumors, Pages 369-381.pdf......Page 1388
Prostate Cancer, Pages 463-473.pdf......Page 1401
Renal Cell Cancer, Pages 61-70.pdf......Page 1412
Rhabdomyosarcoma, Early Onset, Pages 173-177.pdf......Page 1422
Sarcomas of Soft Tissue, Pages 197-203.pdf......Page 1427
Skin Cancer, Non-Melanoma, Pages 235-243.pdf......Page 1434
Testicular Cancer, Pages 363-375.pdf......Page 1443
Wilms Tumor Epidemiology, Pages 533-542.pdf......Page 1456
Acute Lymphoblastic Leukemia in Adults, Pages 1-10.pdf......Page 1466
Acute Lymphoblastic Leukemia in Children, Pages 11-18.pdf......Page 1476
Acute Myelocytic Leukemia, Pages 19-24.pdf......Page 1484
Bladder Cancer Assessment and Management, Pages 205-213.pdf......Page 1490
Bone Tumors, Pages 229-237.pdf......Page 1499
Brain Tumors Epidemiology and Molecular and Cellular Abnormalities, Pages 279-286.pdf......Page 1508
Breast Cancer, Pages 287-299.pdf......Page 1516
Chronic Lymphocytic Leukemia, Pages 497-503.pdf......Page 1529
Chronic Myelogenous Leukemia Etiology, Incidence, and Clinical Features, Pages 505-518.pdf......Page 1536
Chronic Myelogenous Leukemia Prognosis and Current Status of Treatment, Pages 519-524.pdf......Page 1550
Colorectal Cancer Epidemiology and Treatment, Pages 1-8.pdf......Page 1556
Endocrine Tumors, Pages 135-143.pdf......Page 1564
Endometrial Cancer, Pages 145-154.pdf......Page 1573
Esophageal Cancer Treatment, Pages 169-177.pdf......Page 1583
Gastric Cancer Epidemiology and Therapy, Pages 249-252.pdf......Page 1592
Germ Cell Tumors, Pages 287-296.pdf......Page 1596
Head and Neck Cancer, Pages 339-346.pdf......Page 1606
Hepatocellular Carcinoma (HCC), Pages 363-371.pdf......Page 1614
Lymphoma, Hodgkin's Disease, Pages 59-65.pdf......Page 1623
Lymphoma, Non-Hodgkin's, Pages 67-75.pdf......Page 1630
Malignant Mesothelioma, Pages 115-118.pdf......Page 1639
Cytokines Hematopoietic Growth Factors, Pages 41-47.pdf......Page 1643
Differentiation and Cancer Basic Research, Pages 49-63.pdf......Page 1650
Differentiation and the Role of Differentiation Inducers in Cancer Treatment, Pages 65-72.pdf......Page 1665
DNA Methylation and Cancer, Pages 89-95.pdf......Page 1673
Extracellular Matrix and Matrix Receptors Alterations during Tumor Progression, Pages 215-233.pdf......Page 1680
Glutathione Transferases, Pages 297-307.pdf......Page 1699
Glycoproteins and Glycosylation Changes in Cancer, Pages 309-324.pdf......Page 1710
Her2 neu, Pages 387-405.pdf......Page 1726
Insulin-like Growth Factors, Pages 487-492.pdf......Page 1745
Integrin Receptor Signaling Pathways, Pages 493-499.pdf......Page 1751
JakSTAT Pathway, Pages 537-542.pdf......Page 1758
Kinase-Regulated Signal Transduction Pathways, Pages 553-569.pdf......Page 1764
MAP Kinase Modules in Signaling, Pages 119-129.pdf......Page 1781
Protein Kinase Inhibitors, Pages 475-480.pdf......Page 1792
Pyruvate Kinases, Pages 535-547.pdf......Page 1798
Recombination Mechanisms and Roles in Tumorigenesis, Pages 49-59.pdf......Page 1811
Senescence, Cellular, Pages 205-211.pdf......Page 1822
Signal Transduction Mechanisms Initiated by Receptor Tyrosine Kinases, Pages 213-234.pdf......Page 1829
Telomeres and Telomerase, Pages 353-361.pdf......Page 1851
TGFβ Signaling Mechanisms, Pages 377-386.pdf......Page 1860
Transgenic Mice in Cancer Research, Pages 449-458.pdf......Page 1870
Tumor Necrosis Factors, Pages 475-489.pdf......Page 1880
BCR-ABL, Pages 199-204.pdf......Page 1895
Caspases in Programmed Cell Death, Pages 369-373.pdf......Page 1901
Cell Cycle Checkpoints, Pages 383-391.pdf......Page 1906
Cell Cycle Control, Pages 393-403.pdf......Page 1915
Cell-Matrix Interactions, Pages 405-414.pdf......Page 1926
Cellular Responses to DNA Damage, Pages 425-431.pdf......Page 1936
Chromosome Aberrations, Pages 485-596.pdf......Page 1943
c-myc Protooncogene, Pages 555-561.pdf......Page 1955
DNA Tumor Viruses Adenovirus, Pages 97-108.pdf......Page 1962
Epstein–Barr Virus and Associated Malignancies, Pages 155-160.pdf......Page 1974
Hepatitis B Viruses, Pages 347-353.pdf......Page 1980
Hepatitis C Virus (HCV), Pages 355-361.pdf......Page 1987
HIV (Human Immunodeficiency Virus), Pages 407-416.pdf......Page 1994
Human T-Cell Leukemia Lymphotropic Virus, Pages 437-445.pdf......Page 2004
Papillomaviruses, Pages 393-401.pdf......Page 2013
Retroviruses, Pages 167-172.pdf......Page 2022
Viral Agents, Pages 513-525.pdf......Page 2028
Antisense Progress toward Gene-Directed Cancer Therapy, Pages 127-134.pdf......Page 2041
Anti-Vascular Endothelial Growth Factor-Based Angiostatics, Pages 135-141.pdf......Page 2049
APC (Adenomatous Polyposis Coli) Tumor Suppressor, Pages 143-151.pdf......Page 2056
Ataxia Telangiectasia Syndrome, Pages 153-164.pdf......Page 2065
Autocrine and Paracrine Growth Mechanisms in Cancer Progression and Metastasis, Pages 165-177.pdf......Page 2077
Acute Lymphoblastic Leukemia in Adults, Pages 1-10.pdf......Page 2090
Acute Lymphoblastic Leukemia in Children, Pages 11-18.pdf......Page 2100
Acute Myelocytic Leukemia, Pages 19-24.pdf......Page 2108
Adeno-Associated Virus A Vector for High-Efficiency Gene Transduction, Pages 25-33.pdf......Page 2114
Alkylating Agents, Pages 35-42.pdf......Page 2123
All-1, Pages 43-48.pdf......Page 2131
Animal Models for Colon Cancer Chemoprevention, Pages 49-55.pdf......Page 2137
Anthracyclines, Pages 57-61.pdf......Page 2144
Antibodies in the Gene Therapy of Cancer, Pages 63-69.pdf......Page 2149
Antibody–Toxin and Growth Factor–Toxin Fusion Proteins, Pages 71-77.pdf......Page 2156
Anti-idiotypic Antibody Vaccines, Pages 79-87.pdf......Page 2163
Antioxidants Carcinogenic and Chemopreventive Properties, Pages 89-101.pdf......Page 2172
Antisense Medicinal Chemistry, Pages 103-117.pdf......Page 2185
Antisense Nucleic Acids Clinical Applications, Pages 119-125.pdf......Page 2200
BCR-ABL, Pages 199-204.pdf......Page 2207
Bladder Cancer Assessment and Management, Pages 205-213.pdf......Page 2213
Bladder Cancer Epidemiology, Pages 215-221.pdf......Page 2222
Bleomycin, Pages 223-227.pdf......Page 2229
Bone Tumors, Pages 229-237.pdf......Page 2234
Brachytherapy, Pages 239-257.pdf......Page 2243
Brain and Central Nervous System Cancer, Pages 259-270.pdf......Page 2262
Brain Cancer and Magnetic Resonance Spectroscopy, Pages 271-277.pdf......Page 2274
Brain Tumors Epidemiology and Molecular and Cellular Abnormalities, Pages 279-286.pdf......Page 2281
Breast Cancer, Pages 287-299.pdf......Page 2289
Bcl-2 Family Proteins and the Dysregulation of Programmed Cell Death, Pages 179-197.pdf......Page 2302
Camptothecins, Pages 301-309.pdf......Page 2321
Cancer Risk Reduction (DietSmoking CessationLifestyle Changes), Pages 311-317.pdf......Page 2330
Cancer Vaccines Gene Therapy and Dendritic Cell-Based Vaccines, Pages 319-325.pdf......Page 2337
Cancer Vaccines Peptide- and Protein-Based Vaccines, Pages 327-336.pdf......Page 2344
Carbohydrate-Based Vaccines, Pages 337-344.pdf......Page 2354
Carcinogen–DNA Adducts, Pages 345-357.pdf......Page 2362
Carcinogenesis Role of Reactive Oxygen and Nitrogen Species, Pages 359-367.pdf......Page 2375
Caspases in Programmed Cell Death, Pages 369-373.pdf......Page 2384
Cationic Lipid-Mediated Gene Therapy, Pages 375-381.pdf......Page 2389
Cell Cycle Checkpoints, Pages 383-391.pdf......Page 2396
Cell Cycle Control, Pages 393-403.pdf......Page 2405
Cell-Matrix Interactions, Pages 405-414.pdf......Page 2416
Cell-Mediated Immunity to Cancer, Pages 415-424.pdf......Page 2426
Cellular Responses to DNA Damage, Pages 425-431.pdf......Page 2436
Chemical Mutagenesis and Carcinogenesis, Pages 433-447.pdf......Page 2443
Chemoprevention Trials, Pages 457-472.pdf......Page 2458
Chemoprevention, Pharmacology of, Pages 449-455.pdf......Page 2474
Chemotherapy Synergism and Antagonism, Pages 473-484.pdf......Page 2481
Chromosome Aberrations, Pages 485-596.pdf......Page 2493
Chronic Lymphocytic Leukemia, Pages 497-503.pdf......Page 2505
Chronic Myelogenous Leukemia Etiology, Incidence, and Clinical Features, Pages 505-518.pdf......Page 2512
Chronic Myelogenous Leukemia Prognosis and Current Status of Treatment, Pages 519-524.pdf......Page 2526
Cisplatin and Related Drugs, Pages 525-543.pdf......Page 2532
c-mos Protooncogene, Pages 545-553.pdf......Page 2551
c-myc Protooncogene, Pages 555-561.pdf......Page 2560
Colorectal Cancer Epidemiology and Treatment, Pages 1-8.pdf......Page 2567
Colorectal Cancer Molecular and Cellular Abnormalities, Pages 9-21.pdf......Page 2575
Corticosteroids, Pages 23-31.pdf......Page 2588
Cytokine Gene Therapy, Pages 33-40.pdf......Page 2597
Cytokines Hematopoietic Growth Factors, Pages 41-47.pdf......Page 2605
Differentiation and Cancer Basic Research, Pages 49-63.pdf......Page 2612
Differentiation and the Role of Differentiation Inducers in Cancer Treatment, Pages 65-72.pdf......Page 2627
DNA Damage, DNA Repair, and Mutagenesis, Pages 79-87.pdf......Page 2635
DNA Methylation and Cancer, Pages 89-95.pdf......Page 2644
DNA Tumor Viruses Adenovirus, Pages 97-108.pdf......Page 2651
DNA-Based Cancer Vaccines, Pages 73-78.pdf......Page 2663
Dosimetry and Treatment Planning for Three-Dimensional Radiation Therapy, Pages 109-118.pdf......Page 2669
Drug Resistance DNA Sequence Amplification, Pages 119-134.pdf......Page 2679
Endocrine Tumors, Pages 135-143.pdf......Page 2695
Endometrial Cancer, Pages 145-154.pdf......Page 2704
Epstein–Barr Virus and Associated Malignancies, Pages 155-160.pdf......Page 2714
Esophageal Cancer Risk Factors and Somatic Genetics, Pages 161-168.pdf......Page 2720
Esophageal Cancer Treatment, Pages 169-177.pdf......Page 2728
Estrogens and Antiestrogens, Pages 179-188.pdf......Page 2737
ETS Family of Transcription Factors, Pages 189-196.pdf......Page 2747
Ewing's Sarcoma (Ewing's Family Tumors), Pages 197-207.pdf......Page 2755
EWS-ETS Fusion Genes, Pages 209-213.pdf......Page 2766
Extracellular Matrix and Matrix Receptors Alterations during Tumor Progression, Pages 215-233.pdf......Page 2771
Folate Antagonists, Pages 235-241.pdf......Page 2790
fos Oncogene.pdf......Page 2797
Gastric Cancer Epidemiology and Therapy, Pages 249-252.pdf......Page 2803
Gastric Cancer Inherited Predisposition, Pages 253-258.pdf......Page 2807
Gene Therapy Vectors Safety Considerations, Pages 259-265.pdf......Page 2813
Genetic Alterations in Brain Tumors, Pages 267-272.pdf......Page 2820
Genetic Basis for Quantitative and Qualitative Changes in Drug Targets, Pages 273-277.pdf......Page 2826
Genetic Predisposition to Prostate Cancer, Pages 279-285.pdf......Page 2831
Germ Cell Tumors, Pages 287-296.pdf......Page 2838
Glutathione Transferases, Pages 297-307.pdf......Page 2848
Glycoproteins and Glycosylation Changes in Cancer, Pages 309-324.pdf......Page 2859
Graft versus Leukemia and Graft versus Tumor Activity, Pages 325-338.pdf......Page 2875
Head and Neck Cancer, Pages 339-346.pdf......Page 2889
Hepatitis B Viruses, Pages 347-353.pdf......Page 2897
Hepatitis C Virus (HCV), Pages 355-361.pdf......Page 2904
Hepatocellular Carcinoma (HCC), Pages 363-371.pdf......Page 2911
Her2 neu, Pages 387-405.pdf......Page 2920
Hereditary Colon Cancer and DNA Mismatch Repair, Pages 373-379.pdf......Page 2939
Hereditary Risk of Breast and Ovarian Cancer BRCA1 and BRCA2.pdf......Page 2946
HIV (Human Immunodeficiency Virus), Pages 407-416.pdf......Page 2951
Hormonal Carcinogenesis, Pages 41-428.pdf......Page 2961
Hormone Resistance in Prostate Cancer, Pages 429-436.pdf......Page 2973
Human T-Cell Leukemia Lymphotropic Virus, Pages 437-445.pdf......Page 2981
Hyperthermia, Pages 447-459.pdf......Page 2990
Hypoxia and Drug Resistance, Pages 461-467.pdf......Page 3003
Immune Deficiency Opportunistic Tumors, Pages 469-485.pdf......Page 3010
Insulin-like Growth Factors, Pages 487-492.pdf......Page 3027
Integrin Receptor Signaling Pathways, Pages 493-499.pdf......Page 3033
Integrin-Targeted angiostatics, Pages 501-509.pdf......Page 3040
Interferons Cellular and Molecular Biology of Their Actions, Pages 511-521.pdf......Page 3049
Interleukins, Pages 523-535.pdf......Page 3060
JakSTAT Pathway, Pages 537-542.pdf......Page 3073
Kidney, Epidemiology, Pages 543-552.pdf......Page 3079
Kinase-Regulated Signal Transduction Pathways, Pages 553-569.pdf......Page 3089
L-Asparaginase, Pages 1-6.pdf......Page 3106
Late Effects of Radiation Therapy, Pages 7-19.pdf......Page 3112
Li–Fraumeni Syndrome, Pages 21-29.pdf......Page 3125
Liposome-Mediated Gene Therapy, Pages 31-37.pdf......Page 3134
Liver Cancer Etiology and Prevention, Pages 39-44.pdf......Page 3141
Lung Cancer Molecular and Cellular Abnormalities, Pages 45-50.pdf......Page 3147
Lung, Larynx, Oral Cavity, and Pharynx, Pages 51-58.pdf......Page 3153
Lymphoma, Hodgkin's Disease, Pages 59-65.pdf......Page 3161
Lymphoma, Non-Hodgkin's, Pages 67-75.pdf......Page 3168
Macrophages, Pages 77-88.pdf......Page 3177
Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging, Introduction, Pages 89-103.pdf......Page 3189
Magnetic Resonance Spectroscopy of Cancer Clinical Overview, Pages 105-114.pdf......Page 3204
Malignant Mesothelioma, Pages 115-118.pdf......Page 3214
MAP Kinase Modules in Signaling, Pages 119-129.pdf......Page 3218
Melanoma Biology, Pages 131-139.pdf......Page 3229
Melanoma Cellular and Molecular Abnormalities, Pages 141-152.pdf......Page 3238
Melanoma Epidemiology, Pages 153-166.pdf......Page 3250
Metabolic Diagnosis of Prostate Cancer by Magnetic Resonance Spectroscopy, Pages 167-177.pdf......Page 3264
Mismatch Repair Biochemistry and Genetics, Pages 179-185.pdf......Page 3275
Molecular Aspects of Radiation Biology, Pages 187-195.pdf......Page 3282
Molecular Basis for Tumor Immunity, Pages 197-212.pdf......Page 3291
Molecular Epidemiology and Cancer Risk, Pages 213-220.pdf......Page 3307
Molecular Mechanisms of Cancer Invasion, Pages 221-233.pdf......Page 3315
Monoclonal Antibodies Leukemia and Lymphoma, Pages 235-245.pdf......Page 3328
Multidrug Resistance I P-Glycoprotein, Pages 247-254.pdf......Page 3339
Multidrug Resistance II MRP and Related Proteins, Pages 255-267.pdf......Page 3347
Multiple Myeloma, Pages 269-274.pdf......Page 3360
Multistage Carcinogenesis, Pages 275-285.pdf......Page 3366
myb, Pages 287-296.pdf......Page 3377
Neoplasms in Acquired Immunodeficiency Syndrome, Pages 297-302.pdf......Page 3387
Neoplasms of Unknown Primary Site, Pages 303-314.pdf......Page 3393
Neuroblastoma, Pages 315-321.pdf......Page 3405
nm23 Metastasis Suppressor Gene, Pages 323-327.pdf......Page 3412
Non-Hodgkin's Lymphoma and Multiple Myeloma Incidence and Risk Factors, Pages 329-336.pdf......Page 3417
Nutritional Supplements and Diet as Chemoprevention Agents, Pages 337-351.pdf......Page 3425
Ovarian Cancer Diagnosis and Treatment, Pages 353-360.pdf......Page 3440
Ovarian Cancer Molecular and Cellular Abnormalities, Pages 361-368.pdf......Page 3448
p16 and ARF Crossroads of Tumorigenesis, Pages 491-505.pdf......Page 3456
p53 Gene Therapy, Pages 425-432.pdf......Page 3471
Pancreas and Periampullary Tumors, Pages 369-381.pdf......Page 3479
Pancreatic Cancer Cellular and Molecular Mechanisms, Pages 383-391.pdf......Page 3492
Papillomaviruses, Pages 393-401.pdf......Page 3501
PAX3–FKHR and PAX7–FKHR Gene Fusions in Alveolar Rhabdomyosarcoma, Pages 403-408.pdf......Page 3510
Pediatric Cancers, Molecular Features, Pages 409-417.pdf......Page 3516
PET Imaging and Cancer, Pages 419-424.pdf......Page 3525
P-glycoprotein as a General Antiapoptotic Protein, Pages 433-441.pdf......Page 3531
Photodynamic Therapy Basic Principles and Applications to Skin Cancer, Pages 443-451.pdf......Page 3540
Photodynamic Therapy Clinical Applications, Pages 453-462.pdf......Page 3549
Prostate Cancer, Pages 463-473.pdf......Page 3559
Protein Kinase Inhibitors, Pages 475-480.pdf......Page 3570
Proton Beam Radiation Therapy, Pages 481-490.pdf......Page 3576
PTEN, Pages 507-514.pdf......Page 3586
Purine Antimetabolites, Pages 515-525.pdf......Page 3594
Pyrimidine Antimetabolites, Pages 527-534.pdf......Page 3605
Pyruvate Kinases, Pages 535-547.pdf......Page 3613
p16 and ARF Crossroads of Tumorigenesis, Pages 491-505.pdf......Page 3626
p53 Gene Therapy, Pages 425-432.pdf......Page 3641
Pancreas and Periampullary Tumors, Pages 369-381.pdf......Page 3649
Pancreatic Cancer Cellular and Molecular Mechanisms, Pages 383-391.pdf......Page 3662
Papillomaviruses, Pages 393-401.pdf......Page 3671
PAX3–FKHR and PAX7–FKHR Gene Fusions in Alveolar Rhabdomyosarcoma, Pages 403-408.pdf......Page 3680
Pediatric Cancers, Molecular Features, Pages 409-417.pdf......Page 3686
P-glycoprotein as a General Antiapoptotic Protein, Pages 433-441.pdf......Page 3695
Photodynamic Therapy Basic Principles and Applications to Skin Cancer, Pages 443-451.pdf......Page 3704
Photodynamic Therapy Clinical Applications, Pages 453-462.pdf......Page 3713
Prostate Cancer, Pages 463-473.pdf......Page 3723
Protein Kinase Inhibitors, Pages 475-480.pdf......Page 3734
Proton Beam Radiation Therapy, Pages 481-490.pdf......Page 3740
PTEN, Pages 507-514.pdf......Page 3750
Purine Antimetabolites, Pages 515-525.pdf......Page 3758
Pyrimidine Antimetabolites, Pages 527-534.pdf......Page 3769
Pyruvate Kinases, Pages 535-547.pdf......Page 3777
Radiolabeled Antibodies, Overview, Pages 29-40.pdf......Page 3790
Radiation Resistance, Pages 1-11.pdf......Page 3951
Radiobiology, Principles of, Pages 13-28.pdf......Page 3962
Ras Proteins, Pages 41-48.pdf......Page 3802
Recombination Mechanisms and Roles in Tumorigenesis, Pages 49-59.pdf......Page 3810
Renal Cell Cancer, Pages 61-70.pdf......Page 3821
Replication-Selective Viruses for Cancer Treatment, Pages 71-91.pdf......Page 3831
Resistance to Antibody Therapy, Pages 93-98.pdf......Page 3852
Resistance to DNA-Damaging Agents, Pages 99-106.pdf......Page 3858
Resistance to Inhibitor Compounds of Thymidylate Synthase, Pages 107-113.pdf......Page 3866
Resistance to Inhibitors of Dihydrofolate Reductase, Pages 115-127.pdf......Page 3873
Resistance to Topoisomerase-Targeting Agents, Pages 129-141.pdf......Page 3886
Retinoblastoma Tumor Suppressor Gene, Pages 143-152.pdf......Page 3899
Retroviral Vectors, Pages 153-166.pdf......Page 3909
Retroviruses, Pages 167-172.pdf......Page 3923
Rhabdomyosarcoma, Early Onset, Pages 173-177.pdf......Page 3929
Ribozymes and Their Applications, Pages 179-188.pdf......Page 3934
RUNX-CBF Transcription Factors, Pages 189-195.pdf......Page 3944
Signal Transduction Mechanisms Initiated by Receptor Tyrosine Kinases, Pages 213-234.pdf......Page 3978
Skin Cancer, Non-Melanoma, Pages 235-243.pdf......Page 4000
STAT Proteins in Growth Control, Pages 245-252.pdf......Page 4009
Stem Cell Transplantation, Pages 253-263.pdf......Page 4017
Stereotactic Radiosurgery of Intracranial Neoplasms, Pages 265-273.pdf......Page 4028
Steroid Hormones and Hormone Receptors, Pages 275-284.pdf......Page 4037
Sarcomas of Soft Tissue, Pages 197-203.pdf......Page 4047
Senescence, Cellular, Pages 205-211.pdf......Page 4054
T Cells against Tumors, Pages 329-337.pdf......Page 4061
T Cells and Their Effector Functions, Pages 339-351.pdf......Page 4070
Targeted Toxins, Pages 297-306.pdf......Page 4083
Targeted Vectors for Cancer Gene Therapy, Pages 307-318.pdf......Page 4093
Taxol and Other Molecules That Interact with Microtubules, Pages 319-327.pdf......Page 4105
Telomeres and Telomerase, Pages 353-361.pdf......Page 4114
Testicular Cancer, Pages 363-375.pdf......Page 4123
TGFβ Signaling Mechanisms, Pages 377-386.pdf......Page 4136
Thyroid Cancer, Pages 387-392.pdf......Page 4146
TLS–CHOP in Myxoid Liposarcoma, Pages 393-396.pdf......Page 4152
Tobacco Carcinogenesis, Pages 397-406.pdf......Page 4156
Total Body Irradiation, Pages 407-414.pdf......Page 4166
TP53 Tumor Suppressor Gene Structure and Function, Pages 415-431.pdf......Page 4174
Transfer of Drug Resistance Genes to Hematopoietic Precursors, Pages 433-447.pdf......Page 4191
Transgenic Mice in Cancer Research, Pages 449-458.pdf......Page 4206
Tumor Antigens, Pages 459-466.pdf......Page 4216
Tumor Cell Motility and Invasion, Pages 467-473.pdf......Page 4224
Tumor Necrosis Factors, Pages 475-489.pdf......Page 4231
Tumor Suppressor Genes Specific Classes, Pages 491-499.pdf......Page 4246
Vascular Targeting, Pages 501-507.pdf......Page 4255
Vinca Alkaloids and Epipodophyllotoxins, Pages 509-512.pdf......Page 4262
Viral Agents, Pages 513-525.pdf......Page 4266
Wilms Tumor Epidemiology, Pages 533-542.pdf......Page 4279
Wilms Tumor Suppressor WT1, Pages 543-551.pdf......Page 4289
Wnt Signaling, Pages 553-559.pdf......Page 4298
Plate 1, Page 230.pdf......Page 4305
Plate 2, Page 231.pdf......Page 4306
Plate 3, Page 232.pdf......Page 4307
Plate 4, Page 233.pdf......Page 4308
Plate 5, Page 234.pdf......Page 4309
Plate 6, Page 235.pdf......Page 4310
Plate 7, Page 236.pdf......Page 4311
Plate 8, Page 237.pdf......Page 4312
Plate 9, Page 238.pdf......Page 4313
Plate 10, Page 239.pdf......Page 4314
Plate 11, Page 240.pdf......Page 4315
Plate 12, Page 241.pdf......Page 4316