Electroanalysis in Biomedical and Pharmaceutical Sciences: Voltammetry, Amperometry, Biosensors, Applications

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Through this monograph, the pharmaceutical chemist gets familiar with the possibilities electroanalytical methods offer for validated analyses of drug compounds and pharmaceuticals. The presentation focuses on the techniques most frequently used in practical applications, particularly voltammetry and polarography. The authors present the information in such a way that the reader can judge whether the application of such techniques offers advantages for solving a particular analytical problem. Basics of individual electroanalytical techniques are outlined using as simple language as possible, with a minimum of mathematical apparatus. For each electroanalytical technique, the physical and chemical processes as well as the instrumentation are described. The authors also cover procedures for the identification of electroactive groups and the chemical and electrochemical processes involved.

Understanding the principles of such processes is essential for finding optimum analytical conditions in the most reliable way. Added to this is the validation of such analytical procedures. A particularly valuable feature of this book are extensive tables listing numerous validated examples of practical applications. Various Indices according to the drug type, the electroactive group and the type of method as well as a subject and author index are also provided for easy reference.

Author(s): Sibel A. Ozkan, Jean-Michel Kauffmann, Petr Zuman (auth.)
Series: Monographs in Electrochemistry
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2015

Language: English
Pages: 350
Tags: Electrochemistry; Pharmaceutical Sciences/Technology; Pharmacy; Analytical Chemistry

Front Matter....Pages i-xiii
Introduction....Pages 1-5
Polarography in Studies of Pharmaceuticals....Pages 7-44
Electroanalytical Techniques Most Frequently Used in Drug Analysis....Pages 45-81
Solid Electrodes in Drug Analysis....Pages 83-118
Screen-Printed Electrodes (SPE) for Drug Compounds Determination....Pages 119-140
Electrochemical Biosensors for Drug Analysis....Pages 141-186
Electrochemical and Hyphenated Electrochemical Detectors in Liquid Chromatography and Flow Injection Systems for Drug Compound Analysis....Pages 187-233
Electroanalytical Method Validation in Pharmaceutical Analysis and Their Applications....Pages 235-266
Applications for Drug Assays....Pages 267-335
Back Matter....Pages 337-350