This document was uploaded by one of our users. The uploader already confirmed that they had the permission to publish it. If you are author/publisher or own the copyright of this documents, please report to us by using this DMCA report form.

Simply click on the Download Book button.

Yes, Book downloads on Ebookily are 100% Free.

Sometimes the book is free on Amazon As well, so go ahead and hit "Search on Amazon"

Content: Cover -- Contents -- List of Contributors -- Preface -- Christian Pedersen (1926-2003) -- List of Publications by Christian Pedersen -- Aleksander Wieslaw Zamojski (1929-2004) -- Chemistry of Carbohydrate Aziridines -- Abbreviations -- Introduction -- Methods for the Synthesis of Carbohydrate Aziridines -- Reduction of Azidosulfonates -- Reduction of Cyanosulfonates -- Cyclization of N-Substituted Amino Derivatives -- Cyclization Involving Michael Addition -- Staudinger-Type Cyclization -- Mitsunobu Reaction -- Isomerization of Vicinal Aminooxiranes -- Addition of Nitrenes -- General Properties of Carbohydrate Aziridines -- Reactions of Carbohydrate Aziridines -- General Considerations on Reactivity -- Pyranose Aziridines -- Furanose Aziridines -- Exocyclic Aziridines -- Miscellaneous Reactions of Sugar Aziridines -- References -- Synthesis and Transformation of Glycosyl Azides -- Introduction -- Synthesis of Glycosyl Azides -- Synthesis of 1,2-trans Glycosyl Azides from Glycosyl Halides -- Use of Trimethylsilyl Azide for Synthesis of 1,2-trans-Glycosyl Azides -- Synthesis of 1,2-trans-Glycopyranosyl Azides by Intramolecular Rearrangement -- Synthesis of Glycosyl Azides from Glycosyl Derivatives with an Unprotected Anomeric Center, Employing Phospho-Organic Compounds -- Glycals as Starting Materials for Synthesis of 2-Halo-Substituted Glycosyl Azides -- 1,2-cis Glycosyl Azides -- Transformation of Glycosyl Azides -- Reduction of Glycosyl Azides -- [1,3]-Cycloaddition Reactions of Glycosyl Azides -- Reaction of Glycosyl Azides with Phosphines, Leading to Amines, Amides, and Schiff Bases -- Unprotected and Partially Protected Glycosyl Azides as Starting Materials for N-Glycans -- Oxidation of Glycosyl Azides -- Photochemical and Thermochemical Formations of Glycosyl Azides -- Further Reactions of Glycosyl Azides -- Structural Studies of Glycosyl Azides -- Acknowledgements -- References -- Glycol-Cleavage Oxidation* -- Introduction -- Characteristics of Periodate and Lead Tetraacetate Oxidations -- Mechanisms of Glycol Cleavage -- Some General Properties of Cleavage Reactions: Experimental Methods37 -- Oxidations Other Than Glycol Cleavage: ''Overoxidation'' -- Vicinal Diols Resistant to Glycol Cleavage -- Acyclic Alditols and Cyclitols -- Glycosides and Related Alicyclic Compounds -- Reaction Characteristics; Configurational Relationships -- Dialdehydes -- Reducing Sugars -- Introduction -- Monosaccharides and Partially Substituted Derivatives -- Oligosaccharides -- Polysaccharides -- Oxidation Patterns -- End-Group Analysis -- Fragmentation Analysis -- The Barry and Smith Regioselective Degradation Procedures -- Spectroscopic Methods in Perspective -- Application to Biopolymers -- Acknowledgments -- References -- An Expanding View of Aminoglycoside-Nucleic Acid Recognition -- Introduction -- Early Years -- Mechanism of Action -- Pre-Ribosomal Binding: Cellular Membrane Permeation -- Ribosomal RNA Binding -- Major Issues in Aminoglycoside Therapeutic Applications -- Toxicity -- Combating Toxicity -- Aminoglycoside Resistance -- Fighting Resistance with Aminoglycoside Derivatives -- Experimental Techniques for Probing Aminoglycoside-RNA Interactions -- NMR -- X

Author(s): Derek Horton (Eds.)
Series: Advances in Carbohydrate Chemistry and Biochemistry 60
Publisher: AP
Year: 2006

Language: English
Pages: 1-392
City: Oxford, UK

Content:
List of Contributors
Pages ix-x

Preface
Pages xi-xiii
Derek Horton

Christian Pedersen 1926–2003
Pages 1-16
Inge Lundt, Klaus Bock

Aleksander WiesŁaw Zamojski: 1929–2004
Pages 18-25
Sławomir Jarosz, Marek Chmielewski

Chemistry of Carbohydrate Aziridines Review Article
Pages 27-101
Jindřich Karban, Jiří Kroutil

Synthesis and Transformation of Glycosyl Azides Review Article
Pages 103-182
Zoltán Györgydeák, Joachim Thiem

Glycol-Cleavage Oxidation Review Article
Pages 183-250
Arthur S. Perlin

An Expanding View of Aminoglycoside–Nucleic Acid Recognition Review Article
Pages 251-302
Bert Willis, Dev P. Arya

Hevein Domains: An Attractive Model to Study Carbohydrate–Protein Interactions at Atomic Resolution Review Article
Pages 303-354
Jesús Jiménez-Barbero, Francisco Javier Cañada, Juan Luis Asensio, Nuria Aboitiz, Paloma Vidal, Angeles Canales, Patrick Groves, Hans-Joachim Gabius, Hans-Christian Siebert

Author Index
Pages 355-384

Subject Index
Pages 385-392