Dynamic Light Scattering Spectroscopy of the Human Eye

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Blindness or serious vision impairment is one of the most feared disabilities known to humankind. A 2016 report compiled by the National Eye Institute (NEI) of the National Institutes of Health (NIH) and Prevent Blindness America states that although half of all blindness can be prevented, the number of people who suffer vision loss continues to increase. 

The technique of dynamic light scattering (DLS) was developed by physicists in the late 1960s to early 1970s. DLS is now emerging as a potential ophthalmic tool, making possible studies of virtually every tissue and fluid comprising the eye, thus pushing the envelope for broader applications in ophthalmology.

This book presents a comprehensive review of the application of light scattering in clinical use. It is the first of its kind, offering insight to how DLS can be applied to the human eye as well as animals. Chapters discuss DLS in neurological diseases, including protocols, informed consent, and patents. 

Dynamic Light Scattering Spectroscopy of the Human Eye is a must-have resource for physicians, engineers, and physicists interested in the clinical application of DLS to diagnose and potentially treat medical conditions in a non-invasive, quantitative and novel way. 

Author(s): Jeffrey N. Weiss
Publisher: Springer
Year: 2022

Language: English
Pages: 97
City: Cham

Preface
Contents
Chapter 1: Ocular Anatomy
How Does the Eye Work?
Chapter 2: Light Scattering
Summary of Light Scattering in the Eye
Cornea
Lens
Vitreous
Retina
Chapter 3: Dynamic Light Scattering (DLS) Spectroscopy
Analysis
Cumulant Method
CONTIN Algorithm
Further Reading
Chapter 4: Animal Experiments
Chapter 5: Human Studies
Chapter 6: Neurologic Diseases: Protocol
Introduction
Type of Research
Purpose and Objective of the Study
Background of the Study
Study Rationale
Participant Selection
Study Design/Method/Procedures
Summary of Research Design
Performance of Measurements
General Side Effects
Collection and Used of Data
Analysis of Study Results
Storage of Data
Confidentiality of Data
Risk/Benefit Assessment
Adverse Events
Benefits
Participant Recruitment and Informed Consent
Recruiting
Length of Study
Informed Consent/Assent
Chapter 7: Neurologic Diseases: Informed Consent
Introduction
Terms of the Study
Reproductive Information for Females
Benefits/Outcome of Treatment
Description of Procedure
Cost
Collection and Use of Data
Confidentiality of Records
Available Information
Termination
Participant Statement and Authorization
Chapter 8: Patents: Apparatus for the Detection of Diabetes and Other Abnormalities Affecting the Lens of the Eye
Related U.S. Patent Documents
References Cited [Referenced by]
U.S. Patent Documents
Other References
Parent Case Text
Cross-reference to Related Applications
Claims
I Claim
Description
Field of the Invention
Background of the Invention
Summary of the Invention
Brief Description of the Drawings
Detailed Description of the Preferred Embodiment
Chapter 9: Patents: Diabetes Detection Method #1
Related U.S. Patent Documents
Other References
Parent Case Text
Cross-reference to Related Applications
Claims
I Claim
Description
Field of the Invention
Background of the Invention
Summary of the Invention
Brief Description of the Drawings
Detailed Description of the Method
Chapter 10: Patents: Diabetes Detection Method #2
Related U.S. Patent Documents
References Cited [Referenced by]
U.S. Patent Documents
Parent Case Text
Cross-reference to Related Applications
Claims
Description
Field of the Invention
Background of the Invention
Summary of the Invention
Brief Description of the Drawings
Detailed Description of the Method
Chapter 11: Patents: Filed Patent Application—Apparatus and Method for the Detection of Dementia and Retinal Conditions
Field of the Invention
Background of the Invention
Summary of the Invention
Brief Description of the Drawings
Detailed Description
Claims
Bibliography
Index