Author(s): Molema G., Meijer D.K.F.
Series: Methods and Principles in Medicinal Chemistry 12
Publisher: Wiley-VCH
Year: 2001
Language: English
Pages: 406
City: Weinheim ; New York
Frontmatter......Page 1
Preface......Page 5
Foreword......Page 7
List of Contributors......Page 8
Contents......Page 13
Abbreviations and Acronyms......Page 25
1 Drug Targeting: Basic Concepts and Novel Advances......Page 33
2 Brain-Specific Drug Targeting Strategies......Page 55
3 Pulmonary Drug Delivery: Delivery To and Through the Lung......Page 85
4 Cell Specific Delivery of Anti-Inflammatory Drugs to Hepatic Endothelial and Kupffer Cells for the Treatment of Inflammatory Liver Diseases......Page 120
5 Delivery of Drugs and Antisense Oligonucleotides to the Proximal Tubular Cell of the Kidney Using Macromolecular and Pro-drug Approaches......Page 152
6 A Practical Approach in the Design of Colon-specific Drug Delivery Systems......Page 187
7 Vascular Endothelium in Inflamed Tissue as a Target for Site Selective Delivery of Drugs......Page 201
8 Strategies for Specific Drug Targeting to Tumour Cells......Page 228
9 Tumour Vasculature Targeting......Page 261
10 Phage Display Technology for Target Discovery in Drug Delivery Research......Page 283
11 Development of Proteinaceous Drug Targeting Constructs Using Chemical and Recombinant DNA Approaches......Page 302
12 Use of Human Tissue Slices in Drug Targeting Research......Page 336
13 Pharmacokinetic/Pharmacodynamic Modelling in Drug Targeting......Page 359
14 Drug Targeting Strategy: Scrutinize the Concepts Before Screening the Constructs......Page 397
