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Author(s): Chris J. Van Boxtel, Budiono Santoso, I. Ralph Edwards
Edition: 2 Revised
Publisher: IOS Press
Year: 2008
Language: English
Pages: 846
Title page......Page 2
Contents......Page 6
Contributors......Page 10
Foreword to the Second Edition......Page 16
Foreword to the First Edition......Page 18
Preface to the Second Edition......Page 20
Preface to the First Edition......Page 22
Part A Medicinals in Society......Page 26
A Drug Benefits......Page 28
B Drug Risks......Page 34
2 Therapeutics as a Science......Page 40
3 Pharmacoepidemiology and Drug Evaluation......Page 52
4 Economic Evaluation of Pharmaceuticals and Clinical Practice......Page 62
5 Clinical Pharmacology and Drug Policy......Page 82
6 Drug Regulation: History, Present and Future......Page 90
7 Medicines in Developing Countries......Page 104
8 Drug Information......Page 124
9 Drug Development......Page 132
Part B General Clinical Pharmacology......Page 146
10 Clinical Pharmacokinetics......Page 148
11 Clinical Pharmacodynamics......Page 190
12 Drug Therapy in Pediatric Patients......Page 206
13 Drug Therapy in Older Persons......Page 228
14 Adverse Drug Reactions......Page 250
15 Drug–Drug Interactions......Page 272
16 Drug Misuse – Harmful Use, Abuse and Dependence......Page 288
17 Clinical Pharmacology of Poisoning......Page 300
Section II Pharmacotherapeutic Products......Page 312
18 Neurohumoral Transmission......Page 314
19 Autacoids......Page 336
20 Drugs Affecting Cardiovascular and Renal Functions......Page 348
21 Drugs Acting on the Central Nervous System......Page 372
22 Hemopoietic Drugs and Drugs that Affect Coagulation......Page 392
23 Drugs Affecting Gastrointestinal Function......Page 402
24 Hormones and Hormone Antagonists......Page 412
25 Antimicrobial Agents......Page 432
26 Analgesics, Antirheumatics and Drugs for the Treatment of Gout......Page 460
27 Antineoplastic Agents......Page 472
28 Drugs Used for Immunomodulation......Page 490
29 Vitamins......Page 496
30 Dermatologicals and Miscellaneous Agents......Page 504
Section III Treatment of Health Problems......Page 514
31 Symptomatic Treatment......Page 516
32 Emergency Medicine......Page 530
A Treatment and Prophylaxis of Infectious Diseases......Page 546
B Treatment of HIV/AIDS and of Tuberculosis......Page 574
A Pharmacotherapy of Hypertension......Page 596
B
Treatment of Ischemic Heart Disease......Page 612
C
Treatment of Heart Failure......Page 618
D Pharmacological Treatment of Cardiac Arrhythmias......Page 624
E Pharmacological Treatment of Renal Diseases......Page 634
35 Gastrointestinal and Hepatobiliary Disorders......Page 644
36 Pharmacotherapy of Chronic Obstructive Pulmonary Disease and Asthma......Page 662
37 Disorders of Connective Tissue, Bone and Joints......Page 684
38 Treatment of Psychiatric Disorders......Page 700
39 Neurological Diseases......Page 710
40 Drug Use for Malignancies......Page 732
41 Haematological Disorders......Page 754
42 Endocrine Diseases......Page 776
Index......Page 806
