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DNA Topology

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DNA as the genetic material is a topic of intense interest in the 21st century with the familiar and iconic Watson-Crick double helix having a vital importance for its function. However, there are further complexities beyond the double helix, including supercoiling, knotting and catenation, that are less widely appreciated and understood but which are critical to its function. This book explains these topological aspects of DNA structure in a clear and approachable style that will be appreciated by both students and researchers interested in DNA structure and function.

Author(s): Andrew D. Bates, Anthony Maxwell
Edition: New
Publisher: Oxford University Press, USA
Year: 2005

Language: English
Pages: 217

Cover......Page 1
DNA
Topology......Page 4
ISBN 019856709X......Page 5
PREFACE......Page 8
PREFACE (1993)......Page 12
CONTENTS......Page 14
ABBREVIATIONS AND SYMBOLS......Page 18
1
DNA structure......Page 20
2 DNA supercoiling......Page 44
3 DNA on surfaces......Page 102
4 Knots and catenanes......Page 126
5 DNA topoisomerases......Page 144
6 Biological consequences of DNA topology......Page 164
Glossary......Page 206
Index......Page 212