DNA Nanotechnology: From Structure to Function

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DNA nanotechnology: From structure to function presents an overview of various facets of DNA nanotechnology, with a particular focus on their promising applications. This book is composed of three parts. Part I, Elements of DNA Nanotechnology, provides extensive basic information on DNA nanotechnology. Part II, Static and Dynamic DNA Nanotechnology, describes the design and fabrication of static and dynamic DNA nanostructures. Recent advances in DNA origami, DNA walkers and DNA nanodevices are all covered in this part. Part III, Applications of DNA Nanotechnology, introduces a variety of applications of DNA nanotechnology, including biosensing, computation, drug delivery, etc. Together these provide a comprehensive overview of this emerging area and its broad impact on biological and medical sciences.

This book is intended for post-graduates, post-doctoral researchers and research scientists who are interested in expanding their knowledge of DNA nanotechnology. It provides readers an impression of the latest developments in this exciting filed.

Author(s): Chunhai Fan, Di Li (auth.), Chunhai Fan (eds.)
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2013

Language: English
Pages: 362
Tags: Nanotechnology;Biotechnology;Nucleic Acid Chemistry;Nanoscale Science and Technology

Front Matter....Pages i-viii
Front Matter....Pages 1-1
Brief History of DNA Nanotechnology....Pages 3-5
Functional Nucleic Acids for DNA Nanotechnology....Pages 7-28
Selenium Atom-Specific Mutagenesis (SAM) for Crystallography, DNA Nanostructure Design, and Other Applications....Pages 29-56
Liposomes for DNA Nanotechnology: Preparation, Properties, and Applications....Pages 57-76
Manipulation and Isolation of Individual DNA Molecules with Atomic Force Microscope....Pages 77-85
Single-Molecule Mechanics of DNA....Pages 87-112
Microfluidic Tools for DNA Analysis....Pages 113-153
Front Matter....Pages 155-155
DNA-Directed Assembly of Nanophase Materials: An Updated Review....Pages 157-183
Self-Assembled DNA-Inorganic Nanoparticle Structures....Pages 185-205
DNA Origami Nanostructures....Pages 207-224
Design, Fabrication, and Applications of DNA Nanomachines....Pages 225-261
DNA Walking Devices....Pages 263-273
Front Matter....Pages 275-275
Functional DNA-Integrated Nanomaterials for Biosensing....Pages 277-305
Nucleic Acid Enzyme-Based DNA Nanomachine for Biosensing....Pages 307-320
DNA Nanotechnology and Drug Delivery....Pages 321-334
DNA-Nanotube-Enabled NMR Structure Determination of Membrane Proteins....Pages 335-352
Deoxyribozyme-Based Molecular Computation....Pages 353-362