Diabetes: The Biography

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Diabetes is a disease with a fascinating history and one that has been growing dramatically with urbanization. According to the World Health Authority, it now affects 4.6% of adults over 20, reaching 30% in the over 35s in some populations. It is one of the most serious and widespread diseases today. But the general perception of diabetes is quite different. At the beginning of the 20th century, diabetes sufferers mostly tended to be middle-aged and overweight, and could live tolerably well with the disease for a couple of decades, but when it occasionally struck younger people, it could be fatal within a few months. The development of insulin in the early 1920s dramatically changed things for these younger patients. But that story of the success of modern medicine has tended to dominate public perception, so that diabetes is regarded as a relatively minor illness. Sadly, that is far from the case, and diabetes can produce complications affecting many different organs. Robert Tattersall, a leading authority on diabetes, describes the story of the disease from the ancient writings of Galen and Avicenna to the recognition of sugar in the urine of diabetics in the 18th century, the identification of pancreatic diabetes in 1889, the discovery of insulin in the early 20th century, the ensuing optimism, and the subsequent despair as the complexity of this now chronic illness among its increasing number of young patients became apparent. Yet new drugs are being developed, as well as new approaches to management that give hope for the future. Diabetes affects many of us directly or indirectly through friends and relatives. This book gives an authoritative and engaging account of the long history and changing perceptions of a disease that now dominates the concerns of health professionals in the developed world. Diabetes: the biography is part of the Oxford series, Biographies of Diseases, edited by William and Helen Bynum. In each individual volume an expert historian or clinician tells the story of a particular disease or condition throughout history - not only in terms of growing medical understanding of its nature and cure, but also shifting social and cultural attitudes, and changes in the meaning of the name of the disease itself.

Author(s): Robert Tattersall
Series: Biographies of Diseases
Edition: 1
Publisher: Oxford University Press, USA
Year: 2009

Language: English
Pages: 256

Contents......Page 8
List of illustrations......Page 10
Prologue......Page 12
1 The pissing evil: defining the disease......Page 21
2 Unravelling the role of the pancreas......Page 42
3 Insulin: a force of magical activity......Page 63
4 The dark ages......Page 90
5 Treating long-term complications......Page 109
6 Adult-onset diabetes and tablets at last......Page 126
7 At the laboratory bench......Page 147
8 The pharmaceutical era......Page 170
9 Diabetes becomes epidemic......Page 189
Postscript......Page 208
A......Page 212
E......Page 213
G......Page 214
L......Page 215
N......Page 216
R......Page 217
V......Page 218
Notes......Page 220
Further reading......Page 230
D......Page 236
I......Page 237
N......Page 238
T......Page 239
Z......Page 240