Developing Synthetic Transport Systems

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​Understanding the general laws of an effective system for the transport of substances in cells is an important goal of systems and synthetic biology and will help us to answer why the transport subsystem of a cell is arranged as it is. In addition, the construction of models for optimizing transport systems is of considerable importance in the early stages in the development of a functioning protocell. The aim of this book is to describe the latest techniques for the calculation of the optimal parameters of the transport subsystem of a cell at its maximum efficiency. The book will describe linear and nonlinear programming, dynamic programming, game theory for models of ion transport in different types of cells (e.g. mammalian cells, bacteria, plants and fungi). ​

Author(s): Alexey Melkikh, Maria Sutormina (auth.)
Edition: 1
Publisher: Springer Netherlands
Year: 2013

Language: English
Pages: 199
Tags: Biomedicine general; Systems Biology; Cell Biology; Bioinformatics; Cell Physiology

Front Matter....Pages i-vii
Biological Cybernetics and the Optimization Problem of Transport of Substances in Cells....Pages 1-34
Models of Ion Transport in Mammalian Cells....Pages 35-83
Models of Ion Transport and Regulation in Plant Cells and Unicellular Organisms....Pages 85-130
Optimization of the Transport of Substances in Cells....Pages 131-197
Back Matter....Pages 199-199