This updated second edition provides a structured and highly illustrated guide to dermatopathology. It focuses on the most common dermatopathological diagnoses and presents their clinical, histological, and differential diagnostic features of the diseases. New chapters cover various inflammatory diseases such as interstitial granulomatous dermatitis and filler reactions as well as cutaneous neoplasms such as digital papillary adenocarcinoma.
Dermatopathology aims to help readers to rapidly identify patterns and specific diagnostic features. The book is relevant to both practicing and trainee dermatologists and pathologists.
Author(s): Werner Kempf, Markus Hantschke, Heinz Kutzner
Edition: 2
Publisher: Springer
Year: 2022
Language: English
Pages: 307
City: Cham
Preface
Contents
Basic Principles
1 Principles of Diagnosis
2 Skin Biopsy
2.1 Biopsy Techniques
2.2 Fixation
2.3 Embedding and Sectioning
3 Histopathological Techniques
3.1 Staining
3.2 Immunohistochemical Stains
3.3 Immunofluorescence Studies
3.3.1 Direct Immunofluorescence
3.3.2 Indirect Immunofluorescence
3.3.3 Salt-Split Skin
3.4 Molecular Biological Procedures
3.4.1 In Situ Hybridization (ISH)
3.4.2 Fluorescence in Situ Hybridization (FISH)
3.4.3 Polymerase Chain Reaction (PCR)
4 Dermatopathologic Glossary
Inflammatory and Infectious Dermatoses
5 Epidermis: Spongiosis, Acanthosis and Hyperparakeratosis
5.1 Dermatitis
5.2 Prurigo
5.3 Psoriasis
5.4 Pustular Psoriasis
5.5 Pityriasis Rosea
5.6 Cutaneous Fungal Infections
5.7 Human Papilloma Virus-Associated Acanthopapillomas: Verruca Vulgaris and Condyloma Acuminatum
5.8 Molluscum Contagiosum
5.9 Parapoxvirus Infections
6 Epidermis Acantholysis
6.1 Darier Disease
6.2 Hailey-Hailey Disease
6.3 Herpes Virus Infections
7 Bullous Diseases
7.1 Pemphigus Foliaceus
7.2 Pemphigus Vulgaris
7.3 Bullous Pemphigoid
7.4 Dermatitis Herpetiformis
7.5 Porphyria Cutanea Tarda
8 Interface Dermatoses
8.1 Erythema Multiforme
8.2 Pityriasis Lichenoides
8.3 Lichen Planus
8.4 Lichen Sclerosus
8.5 Lupus Erythematosus
8.6 Pigmented Purpuric Dermatoses
8.7 Incontinentia Pigmenti
9 Dermis Vascular Disorders
9.1 Leukocytoclastic Vasculitis
9.2 Granuloma Faciale and Erythema Elevatum et Diutinum
9.3 Polyarteritis Nodosa
9.4 Cryoglobulinemia
10 Dermis Granulomatous Inflammation
10.1 Granuloma Annulare
10.2 Necrobiosis Lipoidica
10.3 Interstitial Granulomatous Dermatitis
10.4 Sarcoidosis
10.5 Foreign Body Granuloma
10.6 Mycobacterial Infections
10.7 Syphilis
10.8 Leishmaniasis
11 Dermis Interstitial Inflammation
11.1 Borreliosis
11.2 Morphea
12 Dermis Diffuse Mixed Inflammatory Infiltrates
12.1 Urticaria
12.2 Acute Febrile Neutrophilic Dermatosis (Sweet Syndrome)
12.3 Eosinophilic Cellulitis (Wells Syndrome)
12.4 Arthropod Assault Reaction
13 Dermis - Degenerative and Metabolic Disorders
13.1 Chondrodermatitis Helicis Nodularis Chronica
13.2 Pseudoxanthoma Elasticum
13.3 Xanthoma
14 Dermis Inflammation of Adnexal Structures
14.1 Folliculitis
14.2 Alopecia Areata
14.3 Lupus Erythematosus of the Scalp
14.4 Folliculitis Decalvans
14.5 Lichen Ruber Planopilaris
15 Subcutaneous Fat - Panniculitis
15.1 Erythema Nodosum
15.2 Erythema Induratum and Nodular Vasculitis
15.3 Lupus Panniculitis
16 Drug Reactions
16.1 Specific Forms
16.2 Unspecific Forms
17 Artifactual Damage
Cysts
18 Epithelial Cysts
18.1 Epidermoid Cyst
18.2 Trichilemmal Cyst
18.3 Steatocystoma
18.4 Apocrine Hidrocystoma
19 Pseudocysts
19.1 Digital Mucous Cyst
Hamartomas and Neoplasms
20 Epidermal Hamartomas and Neoplasms
20.1 Epidermal Nevus
20.2 Nevus Sebaceus
20.3 Seborrheic Keratosis
20.4 Clear Cell Acanthoma
20.5 Porokeratosis
20.6 Actinic Keratosis
20.7 Bowen Disease
20.8 Squamous Cell Carcinoma
20.9 Keratoacanthoma
21 Melanocytic Lesions
21.1 Mucosal Melanotic Macule
21.2 Lentigo Simplex
21.3 Melanocytic Nevi–Junctional and Compound Types
21.4 Melanocytic Nevi–Dermal and Congenital Types
21.5 Halo Nevus
21.6 Blue Nevus
21.7 Dysplastic Melanocytic Nevus
21.8 Spitz Nevus
21.9 Desmoplastic Spitz Nevus
21.10 Pigmented Spindle Cell Nevus (Reed)
21.11 Clonal Nevus
21.12 Lentigo Maligna and Lentigo Maligna Melanoma
21.13 Superficial Spreading Melanoma
21.14 Nodular Melanoma
21.15 Acrolentiginous Melanoma
21.16 Desmoplastic Melanoma
21.17 Cutaneous Clear Cell Sarcoma
22 Adnexal Tumors
22.1 Sebaceous Hyperplasia
22.2 Sebaceous Adenoma
22.3 Pilomatricoma
22.4 Syringoma
22.5 Syringocystadenoma Papilliferum
22.6 Poroma
22.7 Hidradenoma Synonyms: Nodular Hidradenoma, Clear Cell Hidradenoma
22.8 Spiradenoma
22.9 Cylindroma
22.10 Paget Disease
22.11 Digital Papillary Adenocarcinoma
22.12 Trichoblastoma
22.13 Desmoplastic Trichoepithelioma
22.14 Basal Cell Carcinoma
22.15 Fibroepithelioma of Pinkus
22.16 Mixed Tumor of the Skin
23 Soft Tissue Proliferations and Neoplasms
23.1 Scar
23.2 Hypertrophic Scar and Keloid
23.3 Skin Tag Synonym: Fibroma Molle
23.4 Dermatofibroma
23.5 Dermatofibrosarcoma Protuberans
23.6 Atypical Fibroxanthoma
23.7 Leiomyoma
23.8 Nevus Lipomatosus Superficialis
23.9 Lipoma
23.10 Neurofibroma
23.11 Schwannoma Synonym: Neurilemmoma
23.12 Merkel Cell Carcinoma
24 Vascular Tumors
24.1 Hemangioma
24.2 Pyogenic Granuloma (Synonyme: Lobular Capillary Hemangioma)
24.3 Angiokeratoma
24.4 Kaposi Sarcoma
24.5 Angiosarcoma
25 Lymphomas and Pseudolymphomas
25.1 Mycosis Fungoides
25.2 Primary Cutaneous CD30-positive Lymphoproliferative Disorders
25.3 Primary Cutaneous Marginal Zone Lymphoma
25.4 Primary Cutaneous Follicle Center Lymphoma
25.5 Cutaneous Diffuse Large B-cell Lymphoma, Leg Type
25.6 Cutaneous B-cell Pseudolymphoma Syn.: Lymphocytoma Cutis, Lymphadenosis Cutis Benigna When Caused by Borrelial Infections
26 Histiocytoses and Mastocytoses
26.1 Langerhans Cell Histiocytoses
26.2 Juvenile Xanthogranuloma
26.3 Cutaneous Mastocytoses
27 Cutaneous Metastases
Appendix_1
Appendix_2
Index
