Written by renowned authorities in the field, Deep Brain Stimulation in Neurological and Psychiatric Disorders discusses today’s most current and cutting-edge applications of DBS. Initially used to treat Parkinson’s disease and essential tremor, DBS now has new clinical indications, new anatomic targets, and new technologies that enable an expanded role for DBS in the treatment of other movement disorders such as dystonia, and for other neurologic disorders such as epilepsy, Tourette syndrome and cluster headache. Early experience has also been reported for psychiatric syndromes, such as obsessive-compulsive disorder and depression. This important book begins with reviews of the functional anatomy and physiology of motor and nonmotor aspects of the basal ganglia and their connections which underlie the application of DBS to neurological and psychiatric disorders. This is followed by proposed mechanisms of action of DBS based on functional neuroimaging and neurophysiologic studies in animals and man. Discussions of patient selection, preoperative assessment, operative complications and brain targeting are followed by chapters concerning the demands of microelectrode mapping as well as new and emerging brain imaging approaches for target localization inside the operating room. Postoperative management and outcomes are reviewed in a series of chapters concerning immediate and delayed complications. Particularly important chapters on programming, DBS safety with regard to MRI and other electronic devices, neuropsychological sequelae, and quality of life are also included. Finally, new areas of DBS application are addressed by experts with experience in Tourette syndrome, epilepsy, obsessive-compulsive disorder, depression, and cluster headache. Comprehensive and state-of-the-art, Deep Brain Stimulation in Neurological and Psychiatric Disorders provides a balanced and level-headed approach to the use of DBS with emphasis on proper and objective assessment of outcomes, particularly in regard to the new and emerging applications -- all with the main goal of providing patients with some measure of relief from their difficult conditions.
Author(s): Yoland Smith, Thomas Wichmann (auth.), Daniel Tarsy MD, Jerrold L. Vitek MD, PhD, Philip A. Starr MD, PhD, Michael S. Okun MD (eds.)
Series: Current Clinical Neurology
Edition: 1
Publisher: Humana Press
Year: 2008
Language: English
Pages: 601
Tags: Neurology
Front Matter....Pages i-xv
Functional Anatomy and Physiology of the Basal Ganglia: Motor Functions ....Pages 1-32
Functional Anatomy and Physiology of the Basal Ganglia: Non-motor Functions ....Pages 33-62
History of the Therapeutic Use of Electricity on the Brain and the Development of Deep Brain Stimulation....Pages 63-82
Deep Brain Stimulation: Patient Selection in Parkinson's Disease, Other Movement Disorders, and Neuropsychiatric Disorders ....Pages 83-98
Technical Alternatives in Performing Deep Brain Stimulator Implantation....Pages 99-110
Intra-operative Microrecording and Stimulation....Pages 111-134
Complication Avoidance and Management in Deep Brain Stimulation Surgery....Pages 135-150
Mechanisms of Deep Brain Stimulation....Pages 151-177
Functional Imaging of Deep Brain Stimulation: fMRI, SPECT, and PET ....Pages 179-201
Thalamic Deep Brain Stimulation and Essential Tremor....Pages 205-214
Thalamic Deep Brain Stimulation for Other Tremors....Pages 215-227
Thalamic Deep Brain Stimulation for Parkinson's Disease Tremor....Pages 229-241
Globus Pallidus Deep Brain Stimulation for Parkinson's Disease....Pages 243-252
Deep Brain Stimulation of the Subthalamic Nucleus for the Treatment of Parkinson's Disease....Pages 253-276
Deep Brain Stimulation of the Globus Pallidus Pars Interna and Subthalamic Nucleus in Parkinson's Disease: Pros and Cons ....Pages 277-289
Deep Brain Stimulation in Atypical Parkinsonism....Pages 291-303
Deep Brain Stimulation in Dystonia....Pages 305-319
Deep Brain Stimulation in Tourette's Syndrome....Pages 321-332
The Role of Deep Brain Stimulation (DBS) in the Treatment of Postural Instability and Gait Disorders of Parkinson's Disease....Pages 333-358
Deep Brain Stimulation Programming for Movement Disorders....Pages 361-397
Neuropsychological Issues in Deep Brain Stimulation of Neurological and Psychiatric Disorders....Pages 399-452
Deep Brain Stimulation Safety: MRI and Other Electromagnetic Interactions ....Pages 453-472
Deep Brain Stimulation Fault Testing....Pages 473-494
Quality of Life and Cost Effectiveness of Deep Brain Stimulation in Movement Disorders....Pages 495-508
Deep Brain Stimulation in Depression: Background, Progress, and Key Issues ....Pages 511-529
Deep Brain Stimulation in Obsessive-Compulsive Disorder....Pages 531-546
Deep Brain Stimulation for Medically Intractable Cluster Headache....Pages 547-560
Deep Brain Stimulation in Epilepsy....Pages 561-569
The Future of Deep Brain Stimulation....Pages 571-591
Back Matter....Pages 593-601
