Deep brain stimulation (DBS) is increasingly used for the treatment of patients with severe Parkinson's disease and other movement disorders, but the technique and science behind it is still poorly understood by most clinicians. This book is intended to provide an overview of the use of deep brain stimulation for movement disorders and to provide an introduction to the developing areas of DBS for psychiatric disease. The first part of the book covers the varying surgical techniques involved in implanting electrodes into various deep nuclei within the brain. The neurophysiological techniques involved in this process and the complex issue of programming the implanted stimulator in order to optimize therapeutic efficacy and minimize stimulation induced adverse effects. The second part of the book describes how to select appropriate patients for DBS and describes the results of DBS treatment for Parkinson's disease, dystonia and various tremors, as well as psychiatric conditions. Edited by three of the world's leading experts in the DBS field, this pocketbook provides neurologists, trainees, and specialist nurses with an overview of the therapeutics use of DBS.
Author(s): Peter Bain, Tipu Aziz, Xuguang Liu, Dipankar Nandi
Edition: 1
Publisher: Oxford University Press, USA
Year: 2009
Language: English
Pages: 232
Tags: Медицинские дисциплины;Неврология и нейрохирургия;
Contents......Page 6
Preface......Page 10
Contributors......Page 12
Abbreviations......Page 16
Part 1 – DBS – Surgical techniques......Page 18
1 Subthalamic nucleus stimulation in Parkinson’s disease......Page 20
2 Globus pallidus stimulation......Page 28
3 Thalamic stimulation......Page 36
4 Pedunculopontine nucleus DBS in advanced Parkinson’s disease......Page 44
Part 2 – DBS – Operative physiological techniques and post-operative stimulator programming......Page 52
5 Microelectrode recording and microstimulation for target mapping......Page 54
6 Operative physiological techniques: perioperative macroelectrode recording......Page 66
7 Test stimulation......Page 76
8 DBS stimulator programming......Page 82
Part 3 – DBS for movement disorders......Page 90
9 Selecting appropriate Parkinson’s patients for Deep Brain Stimulation (DBS)......Page 92
10 The long term results of STN stimulation for Parkinson’s disease......Page 100
11 The long term results of GPi stimulation for Parkinson’s disease......Page 112
12 Post-STN DBS Parkinson’s disease......Page 118
13 Selecting appropriate dystonic patients for GPi stimulation......Page 124
14 The results of GPi stimulation for generalized dystonia......Page 132
15 The results of GPi stimulation for focal and segmental dystonia......Page 144
16 Selecting appropriate tremor patients for DBS......Page 156
17 The results of DBS for tremor......Page 174
Part 4 – DBS for psychiatric conditions......Page 186
18 Deep brain stimulation for Gilles de la Tourette syndrome......Page 188
19 DBS for obsessive-compulsive disorder......Page 196
20 Cingulate area 25 DBS for depression......Page 204
Part 5 – Mathematical modelling of DBS......Page 210
21 Modelling approaches to DBS......Page 212
Appendix – Useful links......Page 220
D......Page 222
I......Page 223
N......Page 224
R......Page 225
V......Page 226
Z......Page 227
