This book constitutes the refereed proceedings of the 5th International Workshop on Data Integration in the Life Sciences, DILS 2008, held in Evry, France in June 2008.
The 18 revised full papers presented together with 3 keynote talks and a tutorial paper were carefully reviewed and selected from 54 submissions. The papers adress all current issues in data integration and data management from the life science point of view and are organized in topical sections on Semantic Web for the life sciences, designing and evaluating architectures to integrate biological data, new architectures and experience on using systems, systems using technologies from the Semantic Web for the life sciences, mining integrated biological data, and new features of major resources for biomolecular data.
Author(s): Olivier Bodenreider (auth.), Amos Bairoch, Sarah Cohen-Boulakia, Christine Froidevaux (eds.)
Series: Lecture Notes in Computer Science 5109 : Lecture Notes in Bioinformatics
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2008
Language: English
Pages: 209
Tags: Data Mining and Knowledge Discovery; Health Informatics; Database Management; Information Systems Applications (incl.Internet); Computational Biology/Bioinformatics; Computer Appl. in Life Sciences
Front Matter....Pages -
Ontologies and Data Integration in Biomedicine: Success Stories and Challenging Issues....Pages 1-4
BioWarehouse: Relational Integration of Eleven Bioinformatics Databases and Formats....Pages 5-7
Data Integration in the Life Sciences: Fun, Findings and Frustrations....Pages 8-10
Analyzing the Evolution of Life Science Ontologies and Mappings....Pages 11-27
Ontology Design Principles and Normalization Techniques in the Web....Pages 28-43
Exploiting Ontology Structure and Patterns of Annotation to Mine Significant Associations between Pairs of Controlled Vocabulary Terms....Pages 44-60
Automatic Methods for Integrating Biomedical Data Sources in a Mediator-Based System....Pages 61-76
VisGenome and Ensembl: Usability of Integrated Genome Maps....Pages 77-91
An Entity Resolution Framework for Deduplicating Proteins....Pages 92-107
Semantic Representation and Querying of caBIG Data Services....Pages 108-115
SisGen: A CORBA–Based Data Management Program for DNA Sequencing Projects....Pages 116-123
Bgee: Integrating and Comparing Heterogeneous Transcriptome Data Among Species....Pages 124-131
ENFIN - An Integrative Structure for Systems Biology....Pages 132-143
A System for Ontology-Based Annotation of Biomedical Data....Pages 144-152
Bio2RDF : A Semantic Web Atlas of Post Genomic Knowledge about Human and Mouse....Pages 153-160
OMIE: Ontology Mapping within an Interactive and Extensible Environment....Pages 161-168
Chemical Knowledge for the Semantic Web....Pages 169-176
Combining One-Class Classification Models Based on Diverse Biological Data for Prediction of Protein-Protein Interactions....Pages 177-191
Semi Supervised Spectral Clustering for Regulatory Module Discovery....Pages 192-203
UniProtKB/Swiss-Prot: New and Future Developments....Pages 204-206
EBI Proteomics Services....Pages 207-207
Bio-ontologies Tutorial....Pages 208-208
Back Matter....Pages -
