The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings.
This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives.
Key Features:
-Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students.
-Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19.
-Six chapters in the first part which focus on clinical basics of COVID-19.
-Six chapters in the second part which cover broader topics for practical infection control.
-Multiple tables and figures which summarize and highlight important points.
-Presents a summary of the current standards for the evaluation and diagnosis of COVID-19.
-Features a detailed list of references, abbreviations, and symbols.
This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.
Author(s): Neeraj Mittal, Sanjay Kumar Bhadada, O. P. Katare, Varun Garg
Edition: 1
Publisher: Bentham Science Publishers
Year: 2021
Language: English
Tags: COVID-19; Communicable Diseases; Viral Diseases; Virology
Cover
Title
Copyright
End User License Agreement
Contents
Foreword
Preface
List of Contributors
Prevention of COVID-19: Facts to Overcome the Myths
Rajesh Kumar1, Mangesh Pradeep Kulkarni1, Sheetu Wadhwa1 and Soundappan Kathirvel2,*
INTRODUCTION
MEASURES TO PREVENT THE SPREAD, ASSOCIATED MYTHS AND FACTS
Personal Protective Equipment (PPE)
Head Covers
Face Shield
Mask
Goggles
Gloves
Shoe Covers
Gowns or Coveralls
SANITIZATION AND DISINFECTION
Hand Hygiene
For Public
Prevention of COVID-19 Among Frontline Healthcare Workers
Cleaning of Vegetables-Fruits
Safe Handling of Currency and Paper Documents
Cough or Respiratory Etiquettes
Precautions to be Taken While Coughing/Sneezing or Any Physical Contact
Spitting or Littering in Public
Disinfection of Public Places
Disposal and Disinfection of PPEs
WATER TREATMENT AND WASTE MANAGEMENT
Management of Water and Faecal Waste
Safety of Water Supplies
SOCIAL MEASURES
Physical Distancing
Quarantine and Isolation
Home Quarantine
Institutional Quarantine
Staff Guidelines
Utility Guidelines
Lockdown and Travel Restrictions
Zonal Classification of the Geography
PROPHYLAXIS FOR COVID-19
Dietary Recommendations for the Prevention of COVID-19
General Measures
Medicinal Plant Measures/Procedures
Medical Prophylaxis for Healthcare Workers and Contacts of a Positive Patient
REGULAR SCREENING
PRECAUTIONS FOR TRAVEL
CONCLUSION
LIST OF ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Current Treatment Methods for Coronavirus Disease-19
Kuldeep Kumar1, Sonal1, Pankaj Bhatia1, Dhandeep Singh1, Amteshwar S. Jaggi1 and Nirmal Singh1,*
INTRODUCTION
OVERVIEW OF VARIOUS TREATMENT STRATEGIES FOR COVID-19
Hydroxychloroquine
HCQ in Treatment of COVID-19
Remdesivir
Remdesivir in Treatment of COVID-19
Lopinavir/Ritonavir
Lopinavir/Ritonavir in Treatment of COVID-19
Favipiravir
Favipiravir in Treatment of COVID-19
Azithromycin (AZ)
AZ in COVID-19 Treatment
Arbidol
Arbidol in Treatment of COVID-19
Ribavirin
Ribavirin in COVID-19 Treatment
Teicoplanin
Teicoplanin in COVID-19 Treatment
Ivermectin
Ivermectin in Treatment of COVID-19
Nitazoxanide
Nitazoxanide in COVID-19 Treatment
Corticosteroids
Corticosteroids in the Treatment of COVID-19
Immuno Modulating Agents-Interferons (IFN’s)
IFN’s in Treatment of COVID-19
Monoclonal Antibody Therapy
80R Immunoglobulin G1 (IgGI)
CR3014
Monoclonal Antibody Therapy in COVID-19 Treatment
Tocilizumab
Sarilumab
Limitations and Suggestions Regarding mAb’s
Triple Therapy
Miscellaneous Drugs
Herbal Drugs for COVID-19
Glycyrrhizin
Glycyrrhizin in COVID-19
Hesperetin
Baicalin
Scutellarin
Plasma Therapy
Plasma Therapy in the Treatment of COVID-19
Potential of Stem Cell Therapy in COVID-19
BCG Vaccine
VARIOUS REGULATORY GUIDELINES GIVEN BY NIH (NATIONAL INSTITUTE OF HEALTH) FOR TREATMENT OF COVID-19
CONCLUSION
LIST OF ABBREVIATIONS
AUTHORS CONTRIBUTION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
COVID-19 and Mortality
Rimesh Pal1 and Sanjay Kumar Bhadada1,*
INTRODUCTION
REPRESENTING MORTALITY – MORTALITY RATE VS. CASE-FATALITY RATE
FALLACIES IN ESTIMATING MORTALITY USING CASE-FATALITY RATE
REPORTING COVID-19-RELATED DEATHS
COMPARING CASE-FATALITY RATES OF COVID-19 WITH OTHER RELATED VIRAL DISEASES
COMPARING COVID-19 CASE-FATALITY RATES AMONG VARIOUS NATIONS
CAUSES OF DEATH IN COVID-19
PARAMETERS PREDICTING MORTALITY IN COVID-19
Clinical Parameters
Age
Gender
Symptoms
Complications
Comorbid Illness
Smoking
Secondary Infections
Laboratory Parameters
CONCLUSION
ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Long Term Complications of COVID-19
Ankita Sood1, Bimlesh Kumar1,*, Indu Melkani1, Archit Sood2, Pankaj Prashar1, Anamika Gautam1, Kardam Joshi3 and Dhara Patel3
INTRODUCTION
LONG TERM COMPLICATIONS OF COVID-19
COMPLICATIONS OF COVID-19 IN VARIOUS DISEASES
Diabetes Mellitus (DM)
Hematological Complications
Cardiovascular Diseases
Central Nervous System Complications
Viral Encephalitis
Infectious Toxic Encephalopathy and Cerebrovascular Disease
Chronic Kidney Disease (CKD)
Asthma and Respiratory Disorders
Rheumatoid Arthritis (RA)
CONCLUSION
ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Vaccine Development
Priya Sharma1,#, Shivani Joshi1,#, Aishwarya Joshi1, Nikunj Tandel1 and Rajeev K. Tyagi2,*
COVID-19: VACCINE DEVELOPMENT
COVID-19 VACCINE DEVELOPMENT: MODULATING THE HOST IMMUNE SYSTEM
TYPES OF VACCINES AND THEIR CHARACTERISTICS
Live-attenuated Virus and Inactivated Whole Virus Vaccines
Subunit Vaccines
Vaccines Based on Virus-like Particles (VLPs)
Viral Vector-based Vaccines
DNA Vaccines
NOVEL APPROACHES: USAGE OF MULTIDISCIPLINARY FIELDS
Serum Albumin Strategy
Natural Product (Plant) Based Technology
Nanotechnology and Material Science
mRNA Based Approaches
ANIMAL MODELS TO TEST THE IMMUNOGENIC POTENTIAL OF CANDIDATE VACCINE ANTIGENS
Animal Models Currently in Practice
Humanized Mice Models
Novel Approach of Using Zebrafish (Their Advantages)
CURRENT STATUS OF VACCINE DEVELOPMENT
BENCH TO BEDSIDE: OBSTACLES AND OUTCOMES
Lessons from Previous Vaccine Development
LIST OF ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
The Future of COVID-19 Treatment
Sahil Arora1,#, Manvendra Kumar1,#, Gaurav Joshi1,* and Raj Kumar1,*
INTRODUCTION
DRUGS AFFECTING VIRAL REPLICATION AND TRANSLATION IN COVID-19 DISEASE
DRUGS INTERFERING WITH INFLAMMATION AND OVERCOMING CYTOKINE STORM IN COVID-19 DISEASE
ANTICANCER DRUGS IN THE TREATMENT OF COVID-19 DISEASE
ANTIPARASITIC, ANTIPROTOZOAL, AND ANTIFUNGAL DRUGS IN THE TREATMENT OF COVID-19 DISEASE
DRUGS AFFECTING THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN COVID-19
MISCELLANEOUS
DISCUSSION AND CONCLUSION
ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Subject Index
Back Cover
