The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings.
This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives.
Key Features:
- Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students.
- Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19.
-Six chapters in the first part which focus on clinical basics of COVID-19.
-Six chapters in the second part which cover broader topics for practical infection control.
-Multiple tables and figures which summarize and highlight important points.
-Presents a summary of the current standards for the evaluation and diagnosis of COVID-19.
-Features a detailed list of references, abbreviations, and symbols.
This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVID-19 diagnosis and management as part of their clinical training or professional work.
Author(s): Neeraj Mittal, Sanjay Kumar Bhadada, O. P. Katare, Varun Garg
Edition: 1
Publisher: Bentham Science Publishers
Year: 2021
Language: English
Tags: COVID-19; Coronavirus Disease; Virology; Pulmonology
Cover
Title
Copyright
End User License Agreement
Contents
Foreword
Preface
List of Contributors
Chapter 1
Sunishtha1, Govind Singh1 and Sanju Nanda1,*
INTRODUCTION
THE ATHENIAN PLAGUE
PLAGUE OF JUSTINIAN
THE BLACK DEATH
SPANISH FLU
AIDS
SMALLPOX
SARS
SWINE FLU OR H1N1 PANDEMIC
EBOLA
COVID-19
ORIGIN OF CORONAVIRUS
TYPES OF CORONAVIRUSES
DISEASE ASSOCIATED WITH CORONAVIRUSES
MURINE HEPATITIS VIRUS (MHV)
Central Nervous System
Hepatitis
Pneumonitis
BOVINE CORONAVIRUS
HUMAN CORONAVIRUS
ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Chapter 2
Hitesh Malhotra1,*, Anjoo Kamboj1 and Peeyush Kaushik1
INTRODUCTION
GENOMIC STRUCTURE OF CORONAVIRUS
STRUCTURAL PROTEINS
Spike Protein
Small Membrane Protein
Membrane Protein
Hemagglutinin-Esterase
Nucleocapsid and Internal Proteins
Replicase Protein
VIRAL CYCLE
OUTBREAKS OF CORONAVIRUS
Porcine Coronavirus
Avian Coronavirus
Feline Coronavirus
Bovine Coronavirus
Murine Coronavirus
Human Coronavirus
SARS-CoV
MERS-CoV
COVID-19
Introduction
Chronology of COVID-19
Symptoms
Transmission
Treatment
LIST OF ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Chapter 3
Kamya Goyal1,2,#, Shammy Jindal1,#, Tarun Kumar3, Jugnu Goyal4, Reena Sharma5, Ravinder Singh6 and Samir Mehndiratta7,8,*
INTRODUCTION
GEOGRAPHICAL DISTRIBUTION
GLOBAL EPIDEMIOLOGY OF COVID-19
Effect of Age, Sex and other Factors on Covid-19-Related Deaths
COVID-19 CASE COMPARISONS IN DIFFERENT REGION OF WORLD (WORLD HEALTH ORGANIZATION, 2020)
COVID-19 IN INDIA
REPORT BY ICMR ON COVID-19 ABOUT CONTAINMENT ZONE IN INDIA
NATIONAL RESPONSES ON COVID-19 WORLDWIDE
Asia
China
South Korea
Middle Eastern
Iran
Europe
Spain
France
North America
United States
South America
Africa
Oceania
EFFECT OF LOCKDOWN ON COVID-19 CASES IN TOP TEN MOST AFFECTED COUNTRIES OF WORLD
THE ROLE OF WHO AND INGOS FOR PROVIDING DATA IN COVID-19
OUTCOMES FROM SOME PUBLISHED REPORTS ON COVID-19 EPIDEMIOLOGY
Herd Immunity-COVID-19
CONCLUSION
LIST OF ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Chapter 4
Anirban Ghosh1 and Shamsher Singh1,*
INTRODUCTION
TRANSMISSION OF COV
Virus Life Cycle
Role of Structural Proteins in The Pathogenesis
A. Spike Protein
B. Hemagglutinin-Esterase (HE) Protein
C. Membrane (M) Protein
D. Small Envelop (E) Protein
E. Nucleocapsid (N) Protein and Internal (I) Protein
F. Replicase Proteins
G. CoV Associated Protein
Pathophysiology from a Cell Biology Perspective
Phase I. Asymptomatic Stage (First 1-2 Days of Infection)
Phase II. Upper Airway and Conducting Airway Response (Next Few Days)
Phase III. Hypoxia, Ground-glass Infiltrates, Progression to ARDs
CONCLUSION
LIST OF ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Chapter 5
Jasleen Kaur1, Baljinder Singh2, Bikash Medhi3 and Gurpreet Kaur1,*
INTRODUCTION
CLINICAL PRESENTATIONS OF COVID-19 INFECTION
INTER-INDIVIDUAL VARIATIONS IN CLINICAL PRESENTATIONS DUE TO DIFFERENTIAL SUSCEPTIBILITY TOWARDS COVID-19
Neonates or Newborns (Upto 1 Month); Infants (1 Month-2 Years), Children (2-10 Years)
Adolescent (11-19 Years), Young (20-35 Years) and Middle Aged (36-59 Years) Patients
Elderly (>60 Years) and Older (>80 Years) Patients
ACE2
Gender
Blood Group
Previous Immunization
COMORBIDITY
CONCLUSION
LIST OF ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Chapter 6
Richa Deshpande1,#, Aishwarya Joshi1,#, Nikunj Tandel1 and Rajeev K. Tyagi2,*
COVID-19: A PANDEMIC DISEASE
COVID-19: EARLY DETECTION BASED ON SYMPTOMS
Clinical Analysis
Hematological Analysis
Chest CT
COVID-19: MOLECULAR DETECTION OF VIRUS
RT-PCR Based Assays
Loop Mediated Isothermal Amplification (LAMP)
CRISPR-Isothermal Amplification Based Assays
Microarrays
Metagenomic Sequencing Based Methods
Gold Nanoparticles-Based Colorimetric Assay
COVID-19: SERIOLOGICAL AND IMMUNOLOGICAL BASED DETECTION
BIOMARKER IDENTIFICATION: APPROACH OF SEROLOGICAL PLATFORM
Antibody Biomarkers
Antigen Biomarkers
Procalcitonin and Interleukin-6 as Prognostic COVID-19 Biomarkers
SEROLOGICAL AND IMMUNOLOGICAL ASSAYS
Enzyme-linked Immunosorbent Assay (ELISA)
Lateral Flow Immunoassay
Neutralization Assays
Luminescence-based Immunoassays
Biosensor Tests
Rapid Antigen Tests
CONCLUDING REMARKS
LIST OF ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Subject Index
