Controlled-Release Technology. Pharmaceutical Applications

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Content: Overview of controlled-release drug delivery / Ping I. Lee and William R. Good --
Microstructural models for diffusive transport in porous polymers / W. Mark Saltzman, Stephen H. Pasternak, and Robert Langer --
Diffusion in heterogeneous media / Bret Berner, J.C. Keister, and Eugene R. Cooper --
Estimation of rates of drug diffusion in polymers / C.G. Pitt, A.L. Andrady, Y.T. Bao, and N.K.P. Samuel --
Interpretation of drug-release kinetics from hydrogel matrices in terms of time-dependent diffusion coefficients / Ping I. Lee --
Physicochemical models for percutaneous absorption / J. Hadgraft and Richard H. Guy --
Surface chemical analysis of polymeric drug delivery systems by static secondary ion mass spectrometry (SSIMS) and SIMS imaging / M.C. Davies and A. Brown --
Improved method for measuring in vitro diffusion of drugs through human skin / L.R. Brown, J.F. Cline, C.L. Raleigh, and M.B. Henry --
Simplified procedure for measuring controlled-release kinetics / Charles G. Gebelein, Tahseen Mirza, and Robert R. Hartsough --
Thermally reversible gelation characteristics : poly(oxyethylene)-poly(oxypropylene) block copolymer in aqueous solution after exposure to high-energy irradiation / D. Attwood, C.J. Tait, and J.H. Collett --
Release and delayed release of water-soluble drugs from polymer beads with low water swelling / Karl F. Mueller --
Morphine hydrogel suppositories : device design, scale-up, and evaluation / Marion E. McNeill and Neil B. Graham --
Use of bioerodible polymers in self-regulated drug delivery systems / J. Heller, S.H. Pangburn, and D.W.H. Penhale --
Polysaccharides as drug carriers : activation procedures and biodegradation studies / Etienne Schacht, Filip Vandoorne, Joan Vermeersch, and Ruth Duncan --
Microspheres as controlled-release systems for parenteral and nasal administration / S.S. Davis, L. Illum, D. Burgess, J. Ratcliffe, and S.N. Mills --
Enhancing drug release from polylactide microspheres by using base in the microencapsulation process / Jones W. Fong, Hawkins V. Maulding, George E. Visscher, Josephine P. Nazareno, and Jane E. Pearson --
Effects of ethanol on the transport of [beta]-estradiol in hairless mouse skin : comparison of experimental data with a new theoretical model / W.I. Higuchi, U.D. Rohr, S.A. Burton, P. Liu, J.L. Fox, A.H. Ghanem, H. Mahmoud, S. Borsadia, and William R. Good --
Probing the structure of stratum corneum on the molecular level / K. Knutson, S.L. Krill, W.J. Lambert, and W.I. Higuchi --
New liposomal delivery system for controlled drug release / Victoria M. Knepp, Robert S. Hinz, Francis C. Szoka, Jr., and Richard H. Guy --
Enhanced absorption of ionizable drugs from topical dosage forms / Tsuneji Nagai and Toyoaki Ishikura --
Transdermal drug delivery system with enhanced skin permeability / Yei W. Chien and Chia-Shun Lee --
Method to enhance intranasal peptide delivery / Lawrence S. Olanoff and Richard E. Gibson --
Transbuccal absorption of diclofenac sodium in a dog model / C.D. Ebert, V.A. John, P.T. Beall, and K.A. Rosenzweig --
Constant-release diffusion systems : rate control by means of geometric configuration / K.G. Nelson, S.J. Smith, and R.M. Bennett --
Disposable controlled-release device for drug infusion / Paul Y. Wang, Mary C.Y. Lee, and May S.M. Smith.

Author(s): Ping I. Lee and William R. Good (Eds.)
Series: ACS Symposium Series 348
Publisher: American Chemical Society
Year: 1987

Language: English
Pages: 361
City: Washington, DC