Control Theory and Systems Biology

Contents......Page 6
Preface......Page 8
1 A Primer on Control Engineering......Page 14
2 Modeling and Analysis of Stochastic Biochemical Networks......Page 42
3 Spatial Modeling......Page 58
4 Quantifying Properties of Cell Signaling Cascades......Page 82
5 Control Strategies in Times of Adversity......Page 98
6 Synthetic Biology......Page 114
7 Graphs and the Dynamics of Biochemical Networks......Page 138
8 A Control-Theoretic Interpretation of Metabolic Control Analysis......Page 158
9 Robustness and Sensitivity Analyses in Cellular Networks......Page 182
10 Structural Robustness of Biochemical Networks......Page 202
11 Robustness of Oscillations in Biological Systems......Page 238
12 A Theory of Approximation for Stochastic Biochemical Processes......Page 256
13 System-Theoretic Approaches to Network Reconstruction......Page 278
14 Identification of Biochemical Reaction Networks Using a Parameter-Free Coordinate System......Page 310
References......Page 330
Contributors......Page 348
Index......Page 350