The fifth edition of Contact Dermatitis covers in detail every conceivable aspect of irritant and allergic contact dermatitis and its modern-day management. Special emphasis is given to immunological mechanisms, molecular aspects of sensitizers, atypical clinical forms, reactions to medicaments, and occupational and environmental factors. In order to optimize the diagnostic approach, a wide range of information is provided, including a dictionary of contact allergens. Retained chapters from the previous edition have been thoroughly revised to reflect the latest knowledge. Furthermore, completely new chapters have been added on a variety of topics, including genetics, the role of the skin barrier, the link between respiratory symptoms triggered by chemicals and contact dermatitis, and prevention. The editors and authors are all leading practitioners in the field. The comprehensive but approachable text is supplemented by a large number of full color illustrations and tables. Core messages highlight the most important information and will help the reader to gain a better understanding of the subject and greater competence in everyday practice.
Author(s): Jean-Marie Lachapelle (auth.), Jeanne Duus Johansen, Peter J. Frosch, Jean-Pierre Lepoittevin (eds.)
Edition: 5
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2011
Language: English
Pages: 1252
Tags: Dermatology; Allergology; Occupational Medicine/Industrial Medicine
Front Matter....Pages i-xiii
Front Matter....Pages 11-11
Historical Aspects....Pages 1-9
Front Matter....Pages 11-11
Genetics and Individual Predispositions in Contact Dermatitis....Pages 13-42
Mechanisms of Irritant and Allergic Contact Dermatitis....Pages 43-90
Molecular Aspects in Allergic and Irritant Contact Dermatitis....Pages 91-110
Bio-Guided Fractionation and Identification of Allergens in Complex Mixtures and Products....Pages 111-119
Role of the Permeability Barrier in Contact Dermatitis....Pages 121-135
Immediate Contact Reactions....Pages 137-153
Mechanisms of Phototoxic and Photoallergic Reactions....Pages 155-163
Front Matter....Pages 165-165
Histopathological and Immunohistopathological Features of Irritant and Allergic Contact Dermatitis....Pages 167-177
Ultrastructure of Irritant and Allergic Contact Dermatitis....Pages 179-192
Epidemiology....Pages 193-211
Front Matter....Pages 213-213
Skin Penetration....Pages 215-227
Predictive Tests for Irritants and Allergens and Their Use in Quantitative Risk Assessment....Pages 229-239
Allergic Contact Dermatitis in Humans: Experimental and Quantitative Aspects....Pages 241-251
Front Matter....Pages 253-253
Clinical Features....Pages 255-303
Clinical Aspects of Irritant Contact Dermatitis....Pages 305-345
Systemic Contact Dermatitis....Pages 347-360
Phototoxic and Photoallergic Reactions....Pages 361-376
Pigmented Contact Dermatitis and Chemical Depigmentation....Pages 377-393
Hand Eczema....Pages 395-406
Front Matter....Pages 253-253
Protein Contact Dermatitis....Pages 407-413
Noneczematous Contact Reactions....Pages 415-427
Respiratory Symptoms from Fragrances and the Link with Dermatitis....Pages 429-436
Front Matter....Pages 437-437
Patch Testing....Pages 439-464
Atopy Patch Testing with Aeroallergens and Food Proteins....Pages 465-474
Patch Testing in Adverse Drug Reactions....Pages 475-491
Allergens Exposure Assessment....Pages 493-510
Skin Tests for Immediate Hypersensitivity....Pages 511-517
Photopatch Testing....Pages 519-531
Noninvasive Techniques for Quantification of Contact Dermatitis....Pages 533-542
Front Matter....Pages 543-543
Allergens from the European Baseline Series....Pages 545-590
Cosmetics and Skin Care Products....Pages 591-605
Fragrances....Pages 607-627
Hair Dyes....Pages 629-641
Metals....Pages 643-679
Metalworking Fluids....Pages 681-694
Plastic Materials....Pages 695-728
Topical Drugs....Pages 729-762
Dental Materials....Pages 763-791
Clothing....Pages 793-817
Front Matter....Pages 543-543
Shoes....Pages 819-830
Occupational Contact Dermatitis....Pages 831-839
Occupational Contact Dermatitis: Health Personnel....Pages 841-851
Occupational Contact Dermatitis: Chefs and Food Handlers....Pages 853-864
Occupational Contact Dermatitis: Hairdressers....Pages 865-871
Plants and Plant Products....Pages 873-925
Pesticides....Pages 927-936
Contact Allergy in Children....Pages 937-961
Therapy and Rehabilitation of Allergic and Irritant Contact Dermatitis....Pages 963-983
Prevention of Hand Eczema: Gloves, Barrier Creams and Workers’ Education....Pages 985-1016
Prevention of Allergic Contact Dermatitis: Safe Exposure Levels of Sensitizers....Pages 1017-1022
Legislation....Pages 1023-1028
International Comparison of Legal Aspects of Workers’ Compensation for Occupational Contact Dermatitis....Pages 1029-1051
Databases and Networks. The Benefit for Research and Quality Assurance in Patch Testing....Pages 1053-1063
Contact Dermatitis Research Groups....Pages 1065-1070
Patch Test Concentrations and Vehicles for Testing Contact Allergens....Pages 1071-1105
Patch Testing with the Patients’ Own Products....Pages 1107-1119
Dictionary of Contact Allergens: Chemical Structures, Sources, and References....Pages 1121-1248
Back Matter....Pages 1249-1262
