Concepts in Bioinformatics and Genomics

Cover......Page 1
HALF TITLE PAGE......Page 2
TITLE PAGE......Page 4
COPYRIGHT......Page 5
DEDICATION......Page 6
BRIEF CONTENTS......Page 7
TABLE OF CONTENTS......Page 8
PREFACE......Page 14
ACKNOWLEDGMENTS......Page 18
ABOUT THE AUTHORS......Page 20
INTRODUCTION......Page 22
CHAPTER 1: REVIEW OF MOLECULAR BIOLOGY......Page 24
CHAPTER 2: INFORMATION ORGANIZATION AND SEQUENCE DATABASES......Page 44
CHAPTER 3: MOLECULAR EVOLUTION......Page 61
CHAPTER 4: SUBSTITUTION MATRICES......Page 89
CHAPTER 5: PAIRWISE SEQUENCE ALIGNMENT......Page 112
CHAPTER 6: BASIC LOCAL ALIGNMENT SEARCH TOOL (BLAST) AND MULTIPLE SEQUENCE ALIGNMENT......Page 129
CHAPTER 7: PROTEIN STRUCTURE PREDICTION......Page 152
CHAPTER 8: PHYLOGENETICS......Page 191
CHAPTER 9: GENOMICS......Page 233
CHAPTER 10: TRANSCRIPT AND PROTEIN EXPRESSION ANALYSIS......Page 276
CHAPTER 11: BASIC PROBABILITY......Page 307
CHAPTER 12: ADVANCED PROBABILITY FOR BIOINFORMATICS APPLICATIONS......Page 343
CHAPTER 13: PROGRAMMING BASICS AND APPLICATIONS TO BIOINFORMATICS......Page 374
CHAPTER 14: DEVELOPING A BIOINFORMATICS TOOL......Page 430
GLOSSARY......Page 456
CREDITS......Page 466
INDEX......Page 470