This book constitutes the thoroughly refereed post-conference proceedings of the Sixth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2009, held in Genova, Italy, in October 2009. The revised 23 full papers presented were carefully reviewed and selected from 57 submissions. The main goal of the CIBB meetings is to provide a forum open to researchers from different disciplines to present and discuss problems concerning computational techniques in tools for bioinformatics, gene expression analysis and new perspectives in bioinformatics together with 4 special sessions on using game-theoretical tools in bioinformatics, combining Bayesian and machine learning approaches in bioinformatics: state of the art and future perspectives, data clustering and bioinformatics (DCB 2009) and on intelligent systems for medical decisions support (ISMDS 2009).
Author(s): Francesco Pappalardo, Mark Halling-Brown, Marzio Pennisi, Ferdinando Chiacchio (auth.), Francesco Masulli, Leif E. Peterson, Roberto Tagliaferri (eds.)
Series: Lecture Notes in Computer Science 6160 : Lecture Notes in Bioinformatics
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2010
Language: English
Pages: 320
Tags: Computation by Abstract Devices; Algorithm Analysis and Problem Complexity; Pattern Recognition; Database Management; Artificial Intelligence (incl. Robotics); Simulation and Modeling
Front Matter....Pages -
The ImmunoGrid Simulator: How to Use It....Pages 1-19
Improving Coiled-Coil Prediction with Evolutionary Information....Pages 20-32
Intelligent Text Processing Techniques for Textual-Profile Gene Characterization....Pages 33-44
SILACAnalyzer - A Tool for Differential Quantitation of Stable Isotope Derived Data....Pages 45-55
Non-parametric MANOVA Methods for Detecting Differentially Expressed Genes in Real-Time RT-PCR Experiments....Pages 56-69
In Silico Screening for Pathogenesis Related-2 Gene Candidates in Vigna Unguiculata Transcriptome....Pages 70-81
Penalized Principal Component Analysis of Microarray Data....Pages 82-96
An Information Theoretic Approach to Reverse Engineering of Regulatory Gene Networks from Time–Course Data....Pages 97-111
On the Use of Temporal Formal Logic to Model Gene Regulatory Networks....Pages 112-138
Predicting Protein-Protein Interactions with K-Nearest Neighbors Classification Algorithm....Pages 139-150
Simulations of the EGFR - KRAS - MAPK Signalling Network in Colon Cancer. Virtual Mutations and Virtual Treatments with Inhibitors Have More Important Effects Than a 10 Times Range of Normal Parameters and Rates Fluctuations....Pages 151-164
Basics of Game Theory for Bioinformatics....Pages 165-178
Microarray Data Analysis via Weighted Indices and Weighted Majority Games....Pages 179-190
Combining Replicates and Nearby Species Data: A Bayesian Approach....Pages 191-205
Multiple Sequence Alignment with Genetic Algorithms....Pages 206-214
Multiple Clustering Solutions Analysis through Least-Squares Consensus Algorithms....Pages 215-227
Projection Based Clustering of Gene Expression Data....Pages 228-239
Searching a Multivariate Partition Space Using MAX-SAT....Pages 240-253
A Novel Approach for Biclustering Gene Expression Data Using Modular Singular Value Decomposition....Pages 254-265
Using Computational Intelligence to Develop Intelligent Clinical Decision Support Systems....Pages 266-275
Different Methodologies for Patient Stratification Using Survival Data....Pages 276-290
3-D Mouse Brain Model Reconstruction from a Sequence of 2-D Slices in Application to Allen Brain Atlas....Pages 291-303
A Proposed Knowledge Based Approach for Solving Proteomics Issues....Pages 304-318
Back Matter....Pages -
