Computational Cardiovascular Mechanics promotes the application of patient-specific cardiovascular mechanics models to clinical medicine, which aid medical diagnosis and enhance treatment for cardiovascular disease.
Organized in a two-part structure, this volume presents a comprehensive overview of computational modeling from both solid mechanics and fluid dynamics perspectives. Part I offers chapters devoted to various techniques involving finite element modeling of ventricular mechanics and computational fluid dynamics, with a focus in cardiovascular mechanics. Part II covers heart failure applications which utilize techniques in solid mechanics and fluid dynamics. In the former, both diagnostic (i.e., global and regional indices of myocardial contractility) as well as therapeutic approaches (surgical ventricular remodeling procedures, passive ventricular constraint devices, ventricular implantation of biomaterials and cardiac resynchronization therapy) are discussed. In the latter, the fluid mechanics of heart valves is simulated, as are surgical procedures and heart failure-related devices in the form of coronary artery bypass grafting and ventricular assist devices.
Computational Cardiovascular Mechanics is a vital resource for cardiovascular disease researchers who want to learn how to apply computational fluid and/or solid mechanics to the diagnosis and treatment of heart failure.
Author(s): Jonathan F. Wenk, Choon-Sik Jhun, Zhihong Zhang, Kay Sun, Mike Burger, Dan Einstein (auth.), Julius M. Guccione, Ghassan S. Kassab, Mark B. Ratcliffe (eds.)
Edition: 1
Publisher: Springer US
Year: 2010
Language: English
Pages: 320
Tags: Biomedical Engineering; Cardiac Surgery; Theoretical and Applied Mechanics; Engineering Fluid Dynamics
Front Matter....Pages i-xxvii
Front Matter....Pages 1-1
In Vivo Left Ventricular Geometry and Boundary Conditions....Pages 3-21
Imaging-Based Assessment and Modeling of the Structures of the Myocardium....Pages 23-39
Constitutive Equations and Model Validation....Pages 41-54
Determination of Myocardial Material Properties by Optimization....Pages 55-72
Computational Models of Cardiac Electrical Activation....Pages 73-88
Geometrical Features of the Vascular System....Pages 89-102
Vascular Geometry Reconstruction and Grid Generation....Pages 103-119
Governing Equations of Blood Flow and Respective Numerical Methods....Pages 121-139
Fluid–Structure Interaction (FSI) Modeling in the Cardiovascular System....Pages 141-157
Turbulence in the Cardiovascular System: Aortic Aneurysm as an Illustrative Example....Pages 159-176
Front Matter....Pages 177-177
Noninvasive Assessment of Left Ventricular Remodeling: Geometry, Wall Stress, and Function....Pages 179-196
Surgical Left Ventricular Remodeling Procedures....Pages 197-210
Passive Left Ventricular Constraint Devices....Pages 211-226
Left Ventricular Implantation of Biomaterials....Pages 227-238
Computational Modeling of Heart Failure with Application to Cardiac Resynchronization Therapy....Pages 239-253
Computational Modeling of Aortic Heart Valve Mechanics Across Multiple Scales....Pages 255-275
Blood Flow in an Out-of-Plane Aorto-left Coronary Sequential Bypass Graft....Pages 277-295
Computational Fluid Dynamics Models of Ventricular Assist Devices....Pages 297-316
Back Matter....Pages 317-320
