Computational Biomechanics for Medicine: Solid and Fluid Mechanics Informing Therapy

Preface
Contents
Keynote Abstract
Computational Biomechanics Frameworks and Models for Computer-Assisted Therapy and Understanding of Disease Mechanisms
Automatic Framework for Patient-Specific Biomechanical Computations of Organ Deformation
1 Introduction
2 Proposed Framework
2.1 Image Pre-processing
2.2 Model Construction
2.3 Model Solution
3 Craniotomy-Induced Brain Shift Case Study
4 Discussion and Conclusion
References
Computer Simulation of the Resection Induced Brain Shift; Preliminary Results
1 Introduction
2 Methods
2.1 Biomechanical Modelling Strategy
2.2 Construction of the Finite Element Mesh
2.3 Materials Properties
2.4 Boundary Conditions
2.5 Loading
2.6 Computer Simulation
2.7 Image Warping
3 Results
4 Discussion and Conclusions
References
Mandibular Teeth Movement Variations in Tipping Scenario: A Finite Element Study on Several Patients
1 Introduction
2 Related Work
3 Setting up the Finite Element Model
4 Experiments and Results
5 Summary and Conclusion
References
Computational Biomechanics Model for Analysis of Cervical Spinal Cord Deformations Under Whiplash-Type Loading
1 Introduction
2 Methods
2.1 Cervical Spine and Spinal Cord Models
2.2 Demonstration of the Model Application to Evaluation of Spinal Cord Injury Risk: Modelling of Whiplash-Type Experiments
3 Results
3.1 Calibration of Material Properties
3.2 Demonstration of the Model Application to Evaluation of Spinal Cord Injury Risk: Modelling of Whiplash-Type Experiments
4 Discussion
References
Biomechanical Tissue Characterisation, Determining Organ Geometry, and Organ Deformation Measurements
An Unsupervised Learning Based Deformable Registration Network for 4D-CT Images
1 Introduction
2 Methods
2.1 Training Loss
2.2 Training Dataset
2.3 Network Framework
3 Experiments and Results
3.1 Registration
3.2 Interpolation
3.3 Motion Tracking
4 Conclusion
References
3D Reconstruction of Patient-Specific Carotid Artery Geometry Using Clinical Ultrasound Imaging
1 Introduction
2 Materials and Methods
2.1 Clinical Data
2.2 Extraction of Vessel Lumen from US Images Using Deep Learning
2.3 3D Reconstruction of the Carotid Artery
3 Results
3.1 Image Segmentation Results for the Lumen
3.2 Blood Flow Through the 3D Reconstructed Carotid Artery
4 Discussion and Conclusion
References
Evaluation of the Agreement Between Ultrasound-Based and Bi-Planar X-Ray Radiography-Based Assessment of the Geometrical Features of the Ischial Tuberosity in the Context of the Prevention of Seating-Related Pressure Injury
1 Introduction
2 Methods
2.1 Participants and Protocol
2.2 Data Analysis
3 Results
3.1 Assessment of Morphological Parameter
3.2 Impact of Pelvis Angular Position on the Computed Radii of Curvature
4 Discussion
References
Characterising the Soft Tissue Mechanical Properties of the Lower Limb of a Below-Knee Amputee: A Review
1 Introduction
2 Anatomy and Biomechanical Measurements of the Stump of Below-Knee Amputees
2.1 Characterisation of the Reference Geometry and Deformations
2.2 Techniques and Sensors for Measuring the Loads Acting on the Stump
3 Identifying the Mechanical Properties of the Tissues of the Lower Limb
4 Conclusion
References
3D Brain Deformation in Cadaveric Specimens Compared to Healthy Volunteers Under Non-injurious Loading Conditions
1 Introduction
2 Methods
3 Results
4 Discussion
5 Conclusions
References
Index