Written for fellows, practicing nephrologists, and internists who treat patients with disorders affecting the renal system, Comprehensive Clinical Nephrology, 7th Edition, offers a practical approach to this complex field, supported by underlying scientific facts and pathophysiology. World leaders in nephrology provide current information on clinical procedures and conditions, covering everything from fluid and electrolyte disorders to hypertension, diabetes, dialysis, transplantation, and more―all in a single, convenient volume.
Provides a "just right" amount of basic science and practical clinical guidance to help you make efficient and informed decisions.
Contains new chapters on Blood Pressure Management in the Dialysis Patient, Kidney Diseases Associated with Corona Viruses, Ultrasound Imaging in Nephrology, and Radiologic and Nuclear Imaging in Nephrology.
Includes more than 1,500 full-color illustrations that highlight key topics and detail pathogenesis for a full range of kidney conditions and clinical management.
Covers key topics such as COVID-19, chronic kidney disease, end stage kidney disease, kidney transplantation, glomerular disease, onco-nephrology, dialysis, and much more.
Features popular, color-coded algorithms that provide easy access to important content: yellow boxes for general information, green boxes for therapeutic intervention, and blue boxes for necessary investigations.
Includes quick-reference boxes with links to clinical guidelines in all relevant chapters, plus self-assessment questions online.
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Author(s): Richard J. Johnson, Jurgen Floege, Marcello Tonelli
Edition: 7
Publisher: Elsevier
Year: 2023
Language: English
Commentary: TRUE PDF
Tags: Clinical Nephrology; Internal Medicine; Kidney Diseases; Dialysis
Comprehensive Clinical Nephrology, 7e (April 19, 2023)_(0323825923)_(Elsevier) 1_compressed
Cover
IFC
COMPREHENSIVE CLINICALNE PHROLOGY
Copyright
Dedication
Contents
Preface
Contributors
SECTION I Essential Renal Anatomy and Physiology
Renal Anatomy
Renal Physiology
SECTION II Investigation of Renal Disease
Assessment of Glomerular Filtration Rate
Urinalysis
Point of Care Ultrasound in Nephrology
Radiologic and Nuclear Imaging in Nephrology
Kidney Biopsy
SECTION III Fluid and Electrolyte Disorders
Disorders of Extracellular Volume
Disorders of Water Metabolism
Disorders of Potassium Metabolism
Disorders of Calcium, Phosphate, and Magnesium Metabolism
Normal Acid-Base Balance
Metabolic Acidosis
Metabolic Alkalosis
Respiratory Acidosis, Respiratory Alkalosis, and Mixed Acid-Base Disorders
SECTION IV Glomerular Disease
Introduction to Glomerular Disease: Clinical Presentations
Introduction to Glomerular Disease: Histologic Classication and Pathogenesis
Minimal Change Disease
Primary and Secondary (Nongenetic) Causes of Focal and Segmental Glomerulosclerosis
Inherited Causes of Nephrotic Syndrome
Membranous Nephropathy
Immunoglobulin-Mediated Glomerulonephritis With a Membranoproliferative Pattern of Injury and Cryoglobulinemic Glomerulonephriti
Glomerulonephritis Associated With Complement Disorders
Immunoglobulin A Nephropathy and Immunoglobulin A Vasculitis (Henoch-Schönlein Purpura)
Anti–Glomerular Basement Membrane Disease and Goodpasture Disease
Renal and Systemic Vasculitis
Lupus Nephritis
Monoclonal Immunoglobulin–Related Glomerular Diseases and Renal Amyloidosis
Rare Glomerular Disorders
Thrombotic Microangiopathies, Including Hemolytic Uremic Syndrome
SECTION V Diabetic Kidney Disease
Pathogenesis, Clinical Manifestations, and Natural History of Diabetic Kidney Disease
Prevention and Treatment of Diabetic Kidney Disease
Management of Patients With Diabetes and Chronic Kidney Disease
SECTION VI Hypertension
Normal Blood Pressure Control and the Evaluation of Hypertension
Primary Hypertension
Nonpharmacologic Prevention and Treatment of Hypertension
Pharmacologic Treatment of Hypertension
Evaluation and Treatment of Hypertensive Urgencies and Emergencies
Endocrine Causes of Hypertension: Aldosterone
Other Endocrine Causes of Hypertension
Neurogenic Hypertension, Including Hypertension Associated With Stroke or Spinal Cord Injury
Blood Pressure Management in the Dialysis Patient
Renovascular Hypertension, Atherosclerotic Renal Vascular Disease, and Thromboembolic Kidney Disease
SECTION VII Renovascular Disease
Kidney Physiology and Complications in Normal Pregnancy
SECTION VIII Pregnancy and Renal Disease
Pregnancy With Preexisting Kidney Disease
SECTION IX Hereditary and Congenital Diseases of the Kidney
Autosomal Dominant Polycystic Kidney Disease
Other Cystic Kidney Diseases
Alport Syndrome and Other Familial Glomerular Syndromes
Inherited Disorders of Sodium and Water Handling
Fanconi Syndrome and Other Proximal Tubule Disorders
Sickle Cell Diseases and the Kidney
Congenital Anomalies of the Kidney and Urinary Tract
SECTION X Infectious Diseases and the Kidney
Urinary Tract Infections in Adults
Tuberculosis of the Urinary Tract
Fungal Infections of the Urinary Tract
The Kidney in Schistosomiasis
Glomerular Diseases Associated With Infection
Human Immunodeciency Virus Infection and the Kidney
Kidney Diseases Associated With Coronaviruses
SECTION XI Urologic Disorders
Nephrolithiasis and Nephrocalcinosis
Urinary Tract Obstruction
Primary Vesicoureteral Reux and Reux Nephropathy
Urologic Issues for the Nephrologist
SECTION XII Tubulointerstitial and Vascular Diseases
Acute Interstitial Nephritis
Chronic Interstitial Nephritis
Endemic Nephropathies
SECTION XIII Renal Disease and Cancer
Oncology: Kidney Disease in Cancer Patients
Myeloma and the Kidney
Kidney Disease in Liver, Cardiac, Lung, and Hematopoietic Stem Cell Transplantation
SECTION XIV Acute Kidney Injury
Pathophysiology and Etiology of Acute Kidney Injury
Acute Kidney Injury in the Tropics
Diagnosis and Clinical Evaluation of Acute Kidney Injury
Epidemiology and Prognostic Impact of Acute Kidney Injury and Acute Kidney Disease
Prevention and Nondialytic Management of Acute Kidney Injury
Extracorporeal Therapies for Acute Kidney Injury and Heart Failure
Hepatorenal Syndrome
SECTION XV Drug Therapy in Kidney Disease
Principles of Drug Therapy, Dosing, and Prescribing in Chronic Kidney Disease and Kidney Replacement Therapy
Common Issues in Prescribing in Kidney Disease and Kidney Replacement Therapy
Herbal and Over-the-Counter Medicines and the Kidney
SECTION XVI Chronic Kidney Disease and Uremic Syndrome
Epidemiology of Chronic Kidney Disease and Dialysis
Pathophysiology of Disease Progression in Proteinuric and Nonproteinuric Kidney Disease
Slowing the Progression of Kidney Disease
Clinical Evaluation and Management of Chronic Kidney Disease
Pathogenesis and Risk of Cardiovascular Disease in Chronic Kidney Disease
Practical Management of Cardiovascular Disease in Chronic Kidney Disease
Anemia in Chronic Kidney Disease
Other Blood and Immune Disorders in Chronic Kidney Disease
Bone and Mineral Disorders in Chronic Kidney Disease
Neurologic Complications of Chronic Kidney Disease
Nutrition in Chronic Kidney Disease
Dermatologic Manifestations of Chronic Kidney Disease
Acquired Cystic Kidney Disease and Malignant Neoplasms
Section XVii Geriatric and Palliative Nephrology
Geriatric Nephrology
Palliative Nephrology
SECTION XVIII Dialytic Therapies
Approach to Kidney Replacement Therapy
Vascular Access for Hemodialysis
Diagnostic and Interventional Nephrology
Hemodialysis: Principles and Techniques
Hemodialysis: Dialysis Prescription and Adequacy
Acute Complications During Hemodialysis
Peritoneal Dialysis: Principles, Techniques, and Adequacy
Complications of Peritoneal Dialysis
Extracorporeal Therapies for Drug Overdose and Poisoning
Plasma Exchange
SECTION XIX Transplantation
Immunologic Principles in Kidney Transplantation
Immunosuppressive Medications in Kidney Transplantation
Evaluation and Preoperative Management of Kidney Transplant Recipient and Donor
Kidney Transplantation Surgery
Prophylaxis and Treatment of Kidney Transplant Rejection
Infections and Malignancies in the Kidney Transplant Recipient
Cardiovascular Disease and Metabolic Abnormalities in the Kidney Transplant Recipient
Chronic Allograft Injury
Recurrent Disease in Kidney Transplantation
Outcomes of Kidney Transplantation: Identication, Measures, and Evaluation
Self-Assessment Answers
Index
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