A good book for brief intro into pathophysiology, or as a review for those needing a quick review. Not too in depth, nor currently (2006) up to date, but gives a taste of what pathophysiologis about. Also ties in some of the molecular markers into the text. The best part however are the pictures ... a synopsis at a glimps.
Author(s): Stefan Silbernagl, Florian Lang
Edition: 1
Publisher: Thieme
Year: 2000
Language: English
Pages: 416
City: Stuttgart; New York
Front Page......Page 1
Preface......Page 5
Contents......Page 6
Dedication......Page 11
Cell Growth and Cell Adaptation......Page 12
Abnormalities of Intracellular Signal Transmission......Page 16
Necrotic Cell Death......Page 20
Apoptotic Cell Death......Page 22
Development of Tumor Cells......Page 24
Effects of Tumors......Page 26
Aging and Life Expectancy......Page 28
Fever......Page 30
Hyperthermia, Heat Injuries......Page 32
Hypothermia, Cold Injury......Page 34
Obesity, Eating Disorders......Page 36
Overview......Page 38
Erythropoiesis, Anemia......Page 40
Erythrocyte Turnover: Abnormalities, Compensation, and Diagnosis......Page 42
Megaloblastic Anemia Due to Abnormalities in DNA Synthesis......Page 44
Anemias Due to Disorders of Hemoglobin Synthesis......Page 46
Iron Deficiency Anemias......Page 48
Hemolytic Anemias......Page 50
Immune Defense......Page 52
Inflammation......Page 58
Hypersensitivity Reactions (Allergies)......Page 62
Autoimmune Diseases......Page 66
Immune Defects......Page 68
Hemostasis and its Disorders......Page 60
Overview......Page 76
Ventilation, Perfusion......Page 78
Diffusion Abnormalities......Page 80
Distribution Abnormalities......Page 82
Restrictive Lung Disease......Page 84
Obstructive Lung Disease......Page 86
Pulmonary Emphysema......Page 88
Pulmonary Edema......Page 90
Pathophysiology of Breathing Regulation......Page 92
Hypoxia and Hyperoxia......Page 94
Development of Alkalosis......Page 96
Development of Acidosis......Page 98
Effects of Acidosis and Alkalosis......Page 100
Overview......Page 102
Abnormalities of Renal Excretion......Page 104
Pathophysiology of Renal Transport Processes......Page 106
Abnormalities of Urinary Concentration......Page 110
Abnormalities of Glomerular Function......Page 112
Disorders of Glomerular Permselectivity, Nephrotic Syndrome......Page 114
Interstitial Nephritis......Page 116
Acute Renal Failure......Page 118
Chronic Renal Failure......Page 120
Renal Hypertension......Page 124
Kidney Disease in Pregnancy......Page 126
Hepatorenal Syndrome......Page 128
Urolithiasis......Page 130
Disorders of Water and Salt Balance......Page 132
Abnormalities of Potassium Balance......Page 134
Abnormalities of Magnesium Balance......Page 136
Abnormalities of Calcium Balance......Page 138
Abnormalities of Phosphate Balance......Page 140
Pathophysiology of Bone......Page 142
Function of the Gastrointestinal Tract......Page 144
Esophagus......Page 146
Nausea and Vomiting......Page 150
Gastritis......Page 152
Ulcer......Page 154
Disorders After Stomach Surgery......Page 158
Diarrhea......Page 160
Maldigestion and Malabsorption......Page 162
Constipation and (Pseudo-)Obstruction......Page 166
Acute Pancreatitis......Page 168
Chronic Pancreatitis......Page 170
Cystic Fibrosis......Page 172
Gallstone Disease (Cholelithiasis)......Page 174
Cholestasis......Page 178
Portal Hypertension......Page 180
Fibrosis and Cirrhosis of the Liver......Page 182
Liver Failure......Page 184
Overview......Page 186
Phases of Cardiac Action (Cardiac Cycle)......Page 188
Origin and Spread of Excitation in the Heart......Page 190
The Electrocardiogram (ECG)......Page 194
Abnormalities of Cardiac Rhythm......Page 196
Mitral Stenosis......Page 204
Mitral Regurgitation......Page 206
Aortic Stenosis......Page 208
Aortic Regurgitation......Page 210
Circulatory Shunts......Page 212
Arterial Blood Pressure and its Measurement......Page 216
Hypertension......Page 218
Pulmonary Hypertension......Page 224
Coronary Circulation......Page 226
Coronary Heart Disease......Page 228
Myocardial Infarction......Page 230
Heart Failure......Page 234
Pericardial Diseases......Page 238
Circulatory Shock......Page 240
Edemas......Page 244
Atherosclerosis......Page 246
Venous Disease......Page 250
Amino Acids......Page 252
Lipidoses......Page 254
Abnormalities of Lipoprotein Metabolism......Page 256
Gout......Page 260
Wilson's Disease......Page 262
Heme Synthesis, Porphyrias......Page 264
General Pathophysiology of Hormones......Page 266
Abnormalities of Endocrinal Regulatory Circuit......Page 268
Prolactin......Page 270
Somatotropin......Page 272
Adrenocortical Hormones: Enzyme Defects in Formation......Page 274
Adrenocorticoid Hormones: Causes of Abnormal Release......Page 276
Excess Adrenocorticoid Hormones: Cushing's Disease......Page 278
Deficiency of Adrenocorticoid Hormones: Addison's Disease......Page 280
Causes and Effects of Androgen Excess and Deficiency......Page 282
Release of Female Sex Hormones......Page 284
Effects of Female Sex Hormones......Page 286
Intersexuality......Page 288
Causes of Hypothyroidism, Hyperthyroidism and Goitre......Page 290
Effects and Symptoms of Hyperthyroidism......Page 292
Effects and Symptoms of Hypothyroidism......Page 294
Causes of Diabetes Mellitus......Page 296
Acute Effects of Insulin Deficiency (Diabetes Mellitus)......Page 298
Late Complications of Prolonged Hyperglycemia (Diabetes Mellitus)......Page 300
Hyperinsulinism, Hypoglycemia......Page 302
Histamine, Bradykinin, and Serotonin......Page 304
Eicosanoids......Page 306
Overview......Page 308
Pathophysiology of Nerve Cells......Page 310
Demyelination......Page 312
Disorders of Neuromuscular Transmission......Page 314
Diseases of the Motor Unit and Muscles......Page 316
Diagnosis of Motor Unit Diseases......Page 318
Lesions of the Descending Motor Tracts......Page 320
Diseases of the Basal Ganglia......Page 322
Lesions of the Cerebellum......Page 326
Abnormalities of the Sensory System......Page 328
Pain......Page 330
Diseases of the Optical Apparatus of the Eye......Page 332
Diseases of the Retina......Page 334
Visual Pathway and Processing of Visual Information......Page 336
Hearing Impairment......Page 338
Disorders of the Autonomic Nervous System......Page 342
Lesions of the Hypothalamus......Page 344
The Electroencephalogram (EEG)......Page 346
Epilepsy......Page 348
Sleep Disorders......Page 350
Consciousness......Page 352
Aphasias......Page 354
Disorders of Memory......Page 356
Alzheimer's Disease......Page 358
Depression......Page 360
Schizophrenia......Page 362
Dependence, Addiction......Page 364
Cerebrospinal Fluid, Blood-Brain Barrier......Page 366
Cerebrospinal Fluid Pressure, Cerebral Edema......Page 368
Disorders of Cerebral Blood Flow, Stroke......Page 370
Literature......Page 372
Index......Page 375
