Clinical Trials in Hypertension

Compiling descriptions, results, and analyses from 24 complete or soon-to-be-complete influential clinical trials studying the efficacy of pharmacological therapy in hypertension, this detailed reference examines treatment for hypertension from a variety of perspectives, including trials sponsored by both international governments and pharmaceutical firms. Organized to facilitate convenient comparison and evaluation of results for therapeutic decisions, Clinical Trials in Hypertension ·identifies objectives, inclusion/exclusion criteria, baseline characteristics of subjects, and drug regimens ·spotlights trials that established the effectiveness of breakthrough treatments such as treating young hypertensives with diastolic blood pressure elevations ·reviews numerous drug studies-including Heart Attack Primary Prevention in Hypertension (HAPPHY), Metoprolol Atherosclerosis Prevention in Hypertensives (MAPHY), and Treatment of Mild Hypertension Study (TOMHS)-contrasting diuretics, -adrenergic receptor blockers, angiotensin converting enzyme inhibitors, -adrenergic receptor blockers, and calcium antagonists ·considers treatment options and results with older hypertensives ·and more! Reports on the collaboration between the World Health Organization and the International Society of Hypertension pooling data from more than 30 clinical trials currently in progress. Written by over 90 experts and containing more than 1500 references, drawings, tables, and equations, Clinical Trials in Hypertension satisfies the reference needs of cardiologists and cardiovascular specialists, nephrologists, geriatricians, endocrinologists, internists, family practice physicians, pharmaceutical scientists, and graduate and medical school students in these disciplines.