This book provides insights into how to be a productive clinical researcher via real-life case examples of successful clinical research -- and also clinical research gone awry. Through these examples of success and failure, the book develops a blueprint for building a career in clinical research.
Future medical practice depends on the quality of the clinical trials to which drugs, devices, and treatment procedures are subjected today. However, clinical trials are not easy to do, and many physicians and health care providers who attempt clinical research struggle in this endeavor, primarily because of lack of instruction. Clinical Research aims to fill the gap between training and research through case studies of a long-time clinical researcher’s rich and varied experiences.
Author(s): John G. Brock-Utne (auth.)
Edition: 1
Publisher: Springer-Verlag New York
Year: 2015
Language: English
Pages: XX, 181
Tags: Medicine/Public Health, general
Front Matter....Pages i-xx
Case 1: A “Good” Question....Pages 1-3
Case 2: A “Bad” Question....Pages 5-6
Case 3: Why Were 116 Patients Excluded?....Pages 7-8
Case 4: Sometimes a Good Question Evolves from a Bad One....Pages 9-10
Case 5: What Went Wrong?....Pages 11-12
Case 6: Check Your Facts....Pages 13-14
Case 7: All Is Not Lost....Pages 15-16
Case 8: An Important Lesson....Pages 17-18
Case 9: A Lucky Escape....Pages 19-20
Case 10: A Letter or a Full Paper....Pages 21-22
Case 11: This Could Be Serious. Be Prepared....Pages 23-24
Case 12: Not Correct Procedure....Pages 25-26
Case 13: A Lesson Well Learned....Pages 27-28
Case 14: Taking Out a Patent. Should You or Should You Not?....Pages 29-30
Case 15: Taking Out a Patent. Watch Out....Pages 31-32
Case 16: A Laboratory Lesson....Pages 33-34
Case 17: Before You Start Any Research....Pages 35-36
Case 18: An Offer of Employment: What to Look For....Pages 37-38
Case 19: What Should You Do?....Pages 39-40
Case 20: Who to Trust....Pages 41-42
Case 21: Elementary....Pages 43-44
Case 22: Never Give Up....Pages 45-47
Case 23: How Long Should a Study Go On?....Pages 49-50
Case 24: What to Do?....Pages 51-52
Case 25: To What Journal Should You Send Your Work?....Pages 53-56
Case 26: A Drug-Sponsored Trial....Pages 57-58
Case 27: The Difference Between Research and Quality Assurance/Improvement....Pages 59-61
Case 28: Stopping a Clinical Study....Pages 63-65
Case 29: Controversy....Pages 67-69
Case 30: The P Value....Pages 71-73
Case 31: How Many Authors?....Pages 75-78
Case 32: If You Injure Your Patient....Pages 79-80
Case 33: Multicenter Trials....Pages 81-83
Case 34: Unprofessional Behavior....Pages 85-86
Case 35: Tips on How to Get the Institutional Review Board (IRB) Submission Completed and Passed....Pages 87-90
Case 36: How to Perform and Report the Result of a Survey....Pages 91-93
Case 37: Validity of the Cricoid Pressure (Sellick’s Maneuver)....Pages 95-97
Case 38: Another Unprofessional Behavior....Pages 99-100
Case 39: A Dataset....Pages 101-102
Case 40: Taking Over an Ongoing Clinical Trial....Pages 103-104
Case 41: Should You Do a Pilot Study in This Proposed Trial?....Pages 105-107
Case 42: An Inconclusive Result (Negative Result): What to Do....Pages 109-111
Case 43: Retrospective Studies: What to Watch Out For....Pages 113-115
Case 44: Plagiarism....Pages 117-120
Case 45: Pediatric Research....Pages 121-123
Case 46: Your Paper Is Rejected. What to Do....Pages 125-126
Case 47: You Disagree with a Conclusion of a Published Article....Pages 127-128
Case 48: Is This a Good Study?....Pages 129-130
Case 49: Meta-analysis of Randomized Controlled Trials....Pages 131-134
Case 50: Is the Title of a Paper or Grant Important?....Pages 135-137
Case 51: Sampling and Subjects....Pages 139-140
Case 52: What Not to Do If You Are a Mentor....Pages 141-142
Case 53: Be Aware....Pages 143-144
Case 54: A Statistical Impasse....Pages 145-146
Case 55: A Bad Outcome....Pages 147-148
Case 56: A Case Report....Pages 149-151
Case 57: Are Case Reports Becoming Extinct?....Pages 153-154
Case 58: A Clinical Pharmacology Study....Pages 155-156
Case 59: Watch Out....Pages 157-159
Case 60: A New Equipment....Pages 161-162
Case 61: Those That Ignore the Past....Pages 163-164
Case 62: What Are the Safety Data for This Formulation?....Pages 165-167
Case 63: This Is a Test to See What You Have Learned....Pages 169-170
Back Matter....Pages 171-181
