Designated a Doody's Core Title!
The third edition of this award-winning text provides new and updated knowledge about genetics issues relevant to nursing practice. Read in sequence or used as a reference, this is a comprehensive overview of how genetics affetcs the care that nurses provide. In addition to a summary of basic human genetics and discussion of the Human Genome Project, this new edition includes the latest research findings and implications about inheritance, major genetic disorders (cytogenetics or chromosomal, inherited biochemical, and congenital anomalies), and genetics in twin studies. A consideration of the ethical impact of genetics on society and future generations, as well as information on assisted reproduction round out the overview.
Includes over 100 illustrations and photos of specific genetic disorders; tables and figures on the distribution of disease; and an extensive appendix listing associations, organizations, and websites relevant to genetics.
Author(s): Felissa R. Lashley RN PhD ACRN FACMG CIC
Series: Lashley, Clinical Genetics in Nursing Practice
Edition: 3
Publisher: Springer Publishing Company
Year: 2005
Language: English
Commentary: 50237
Pages: 587
Contents......Page 6
Introduction......Page 8
List of Tables......Page 10
List of Figures......Page 12
Part I: Basics of Genetics and Human Genetics......Page 14
1 Human Genetic Disease......Page 16
2 Basic and Molecular Biology: An Introduction......Page 28
3 Human Variation and its Applications......Page 47
4 Gene Action and Patterns of Inheritance......Page 59
Part II: Major Genetic Disorders......Page 92
5 Cytogenetic Chromosome Disorders......Page 94
6 Inherited Biochemical Disorders......Page 136
7 Birth Defects and Congenital Anomalies......Page 160
Part III: Assessing and Intervening with Clients and Families at Genetic Risk......Page 174
8 Impact of Genetic Diseases on the Family Unit: Factors Influencing Impact......Page 176
9 Assessment of Genetic Disorders......Page 208
10 Genetic Counseling......Page 228
11 Genetic Testing and Screening......Page 246
12 Prenatal Detection and Diagnosis......Page 299
13 The Vulnerable Fetus......Page 323
14 Reproductive and Genetic Effects of Environmental Chemicals and Agents......Page 358
15 Therapeutic Modalities......Page 373
Part IV: The Role of Genetics in Common Situations, Conditions, and Diseases......Page 390
16 Genetics and the Common Diseases......Page 392
17 Twins, Twin Studies, and Multiple Births......Page 396
18 Drug Therapy and Genetics: Pharmacogenetics and Pharmacogenomics......Page 402
19 Genetics and the Immune System......Page 419
20 Mental Retardation......Page 434
21 Aging, Longevity, and Alzheimer Disease......Page 444
22 Emphysema, Liver Disease, and Alpha-1 Antitrypsin Deficiency......Page 453
23 Cancer......Page 461
24 Diabetes Mellitus......Page 489
25 Mental Illness and Behavior......Page 498
26 Heart Disease......Page 507
Part V: In Closing......Page 522
27 Genes and Future Generations......Page 524
A......Page 536
C......Page 537
E......Page 538
H......Page 539
M......Page 540
N......Page 541
R......Page 542
T......Page 543
Z......Page 544
Appendices......Page 546
Appendix A: Useful Genetic Web Sites for Professional Information......Page 547
Appendix B: Organizations and Groups with Web Sites that Provide Information, Products, and Services for Genetic Conditions......Page 548
A......Page 570
B......Page 571
C......Page 572
E......Page 574
G......Page 575
H......Page 577
L......Page 578
M......Page 579
P......Page 580
S......Page 582
V......Page 583
Z......Page 584
