Clinical Case Studies on Medication Safety provides real and simulated scenarios about safety issues related to medication, including Adverse Drug Reactions (ADRs), medication errors, and Drug Related Problems (DRPs). The book explains real-life case management, including details about adverse drug reactions, mistakes during drug administration, drug avoidance, and drug-drug interactions with a goal of improving patient care. With over 150 case studies, including cases from alternative medicine and traditional medicine, this book will help medical and health sciences educators, students, healthcare professionals, and other readers apply their knowledge and skills to solve cases for better patient care.
Author(s): Yaser Mohammed Al-Worafi
Publisher: Academic Press
Year: 2023
Language: English
Pages: 506
City: London
Cover
Clinical Case Studies on Medication Safety
Copyright
Dedication
Contributors
Preface
Acknowledgments
Introduction to the medication safety and the importance of clinical case studies
Background
The scope of the present textbook
Key features
References
Adverse drug reactions (ADRs) case studies: Mild ADRs
Background
Terminologies
Factors affecting the development of adverse drug reactions (ADRs)
Prevention of adverse drug reactions (ADRs) prevention and management
Cases
Case 1. Case of nausea-Metformin
Case 2. Case of vomiting-Amoxicillin/clavulanate
Case 3. Case of ankle edema-Amlodipine
Case 4. Case of headache-Sildenafil
Case 5. Case of constipation-Iron
Case 6. Case of diarrhea-Amoxicillin
Case 7. Case of stomach pain-Ibuprofen
Case 8. Case of skin burning and reddened-Salicylic acid
Case 9. Case of muscle pain-Statin
Case 10. Case of skin dryness-Isotretinoin
Conclusion
Educational resources
References
Further Reading
Adverse drug reactions (ADRs) case studies: Moderate ADRs
Background
Classifications of adverse drug reactions
Management of adverse drug reactions
Cases presentations
Case studies
Case of drug allergies, antibiotics, penicillin
Case of drug-drug/herbal interactions, CYP450 inducers-St Johns Wort, warfarin
Case of acute kidney injuries, contrast media
Case of hyperkalemia, aldosterone receptor antagonists-Spironolactone
Case of hypoglycemia, sulfonylureas-Glimepiride
Case of acute bleeding, DOACs-Apixaban
Case of withdrawal effects, steroids-Prednisone
Case of significant side effects, methotrexate
Case of narrow therapeutic index drugs, digoxin
Case of QTC prolongation, amiodarone/ciprofloxacin
Case of myopathy due to poor function phenotype reduced hepatic uptake of the active form of Simvastatin
Case of DPYD genotype: 5-FU intermediate metabolizer and Diarrhea due to 5-FU accumulation
Conclusion
Educational resources
References
Adverse drug reactions (ADRs) case studies: Severe ADRs
Background
Terminologies
Factors affecting the development of adverse drug reactions (ADRs)
Prevention of adverse drug reactions (ADRs) prevention and management
Cases
Case 1. Case of acute kidney injury-Ceftriaxone
Case 2. Case of gastrointestinal bleeding-Aspirin
Case 3. Case of gastrointestinal bleeding-Naproxen
Case 4. Case of vision impairment-Sildenafil
Case 5. Case of hepatotoxicity-Ketoconazole
Case 6. Case of hepatotoxicity-Statin
Case 7. Case of rhabdomyolysis-Statin
Case 8. Case of electrolyte abnormalities and rhabdomyolysis-Furosemide
Case 9. Case of hepatotoxicity-Paracetamol
Case 10. Case of electrolyte abnormalities-Laxatives
Conclusion
Educational resources
References
Further reading
Medication errors case studies: Prescribing, transcribing, and prescriptions/orders writing errors
Background
Terminologies
Cases
Case 1. Case of stable angina
Case 2. Case of asthma
Case 3. Case of diabetes mellitus type 2, hypertension, and dyslipidemia
Case 4. Case of epilepsy
Case 6. Case of dyslipidemia
Case 7. Case of epilepsy
Case 8. Case of dyslipidemia
Prescription writing errors
Conclusion
Educational resources
References
Medication errors case studies: Dispensing and administration errors
Background
Terminologies
Cases: Dispensing errors
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Cases: Administration errors
Case 1
Case 2
Case 3
Case 4
Conclusion
Educational resources
References
Medication errors case studies: Monitoring and counseling errors
Background
Terminologies
Cases: Monitoring errors
Case 1
Case 2
Case 3
Case 4. Case of diabetes mellitus type 2 and hypertension
Case 5
Case 6
Cases: Education and counseling errors
Case 1
Case 2
Case 3
Case 4
Conclusion
Educational resources
References
Further reading
Medication errors case studies: Medication reconciliation errors
Background
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
Educational resources
References
Drug interactions case studies
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
Educational resources
References
Further reading
Adherence, compliance, and persistence case studies
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
Educational resources
References
Further reading
Drug-related problems case studies: Part I
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Conclusion
Educational resources
References
Drug-related problems case studies: Part II
Background
Cases
Case 1
Case 2
Case 3
Case 5
Conclusion
Educational resources
References
Further reading
Counterfeit and substandard medications case studies
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Conclusion
Educational resources
References
Medications misuse and abuse case studies
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
Educational resources
References
Further reading
Medications safety for special population case studies: Geriatrics
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
Educational resources
References
Medications safety for special population case studies: Pediatrics
Background
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
References
Medications safety for special population case studies: Pregnancy
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
Educational resources
References
Medications safety for special population case studies: Lactation
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Conclusion
Educational resources
References
Herbal medicines case studies: Part I
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Conclusion
Educational resources
References
Further reading
Herbal medicines case studies: Part II
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Conclusion
Educational resources
References
Further reading
Antibiotics case studies: Community pharmacies and primary care and public
Background
Terminologies
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Conclusion
Educational resources
References
Further reading
Antibiotics safety case studies: Hospitals
Background
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
References
Vaccines safety case studies
Background
Terminologies
Prevention of adverse drug reactions (ADRs) prevention and management
Cases
Case 1
Case 2
Case 3
Case 4
Case 5
Conclusion
Educational resources
References
Further reading
Index
