Clinical cardiologists are encountering an important challenge in the care of families with inherited cardiac diseases. The majority of the inherited cardiac diseases causing sudden death express themselves at variable ages in the form of altered muscle function – for instance hypertrophic or dilated cardiomyopathy – or in the form of arrhythmias, including Brugada syndrome and long QT syndrome. Clinical and genetic research is continuously ongoing not only to identify those at risk but also to better define their level of risk. Deciding on the most appropriate clinical tests is a challenge in inherited diseases. It is in this situation that specialized clinical-genetic clinics have appeared to provide a complete assessment of patients and family members. The clinicians in the community, faced with a growing number of questions and doubts in the caring of these individuals, are increasingly using the expertise of these centers to address the clinical decisions in their patients.
Clinical Approach to Sudden Cardiac Death Syndromes details the main guidelines to clinicians on how to approach the patients and family members with an inherited disease. It also includes an in-depth review of what is currently available to assist in the diagnosis, prevention and risk stratification in sudden cardiac death. This book is therefore an essential reference for all cardiologists and electrophysiologists, but also this will be important reading for general practice physicians who may be responsible for the identification of families at risk.
Author(s): Sumeet S. Chugh, Carmen Teodorescu, Audrey Evanado, Kyndaron Reinier (auth.), Ramon Brugada (eds.)
Edition: 1
Publisher: Springer-Verlag London
Year: 2010
Language: English
Pages: 340
Tags: Cardiology; Internal Medicine; Emergency Medicine; General Practice / Family Medicine; Sports Medicine; Epidemiology
Front Matter....Pages i-xvi
Front Matter....Pages 1-1
Sudden Unexplained Death in the Community....Pages 3-6
Sudden Infant Death Syndrome: Gene-Environment Interactions....Pages 7-21
Front Matter....Pages 24-24
Unexplained Syncope....Pages 25-35
Arrhythmias and Sudden Cardiac Death in Adult Congenital Heart Disease....Pages 37-56
Endurance Sport Practice and Arrhythmias....Pages 57-72
Electrocardiograms Not to Miss....Pages 73-90
Sudden Cardiac Death in Forensic Pathology....Pages 91-110
Front Matter....Pages 111-111
Genetic Studies....Pages 113-120
The Long QT Syndrome....Pages 121-129
Brugada Syndrome....Pages 131-148
Short QT Syndrome....Pages 149-156
Catecholaminergic Polymorphic Ventricular Tachycardia....Pages 157-162
Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia....Pages 163-171
Atrial Fibrillation....Pages 173-178
Dilated Cardiomyopathy....Pages 179-190
Hypertrophic Cardiomyopathy....Pages 191-201
Genetic Lipoprotein Disorders and Cardiovascular Disease....Pages 203-221
A Systematic Approach to Marfan Syndrome and Hereditary Forms of Aortic Dilatation and Dissection....Pages 223-232
Inherited Metabolic Diseases: Emphasis on Myocardial Disease and Arrhythmogenesis....Pages 233-258
Clinical Genetics in Congenital Heart Disease....Pages 259-270
Front Matter....Pages 272-272
Pharmacogenomics....Pages 273-287
Polygenic Studies in the Risk of Arrhythmias....Pages 289-296
The Genetic Challenge of Coronary Artery Disease....Pages 297-307
Front Matter....Pages 310-310
Psychological Implications of Genetic Investigations....Pages 311-316
Participation in Recreational Sports for Young Patients with Genetic Cardiovascular Diseases....Pages 317-326
Genetic Counseling in Cardiovascular Conditions....Pages 327-335
Back Matter....Pages 337-340
