This basic but comprehensive text is aimed at all healthcare professionals who need a clear understanding of medical virology. Written by two highly experienced virologists, the book is divided into five sections: 1) Individual viruses; 2) Other related agents; 3) Clinical syndromes; 4) Diagnostic techniques; 5) Patient management. The individual virus chapters provide information on incubation period, infectivity, control of infection and management. The clinical syndrome chapters provide information on the clinical presentation of disease, thus enabling the reader to search according to patient symptoms rather than referring to several individual virus chapters. The standard chapter formats, simple language and liberal use of tables, figures and algorithms enable quick access to key information, and the comprehensive coverage of all viral agents is unique in a practical guide of this size.
Author(s): Goura Kudesia, Tim Wreghitt
Series: Cambridge Clinical Guides
Edition: 1
Publisher: Cambridge University Press
Year: 2009
Language: English
Pages: 281
Cover......Page 1
Half-title......Page 3
Title......Page 5
Copyright......Page 6
Contents......Page 7
Plates......Page 10
Preface......Page 11
Acknowledgements......Page 12
Viral taxonomy......Page 13
Transcription and translation of viral genome......Page 15
Viral pathogenesis......Page 16
Viral persistence......Page 17
Conclusion......Page 18
Symptoms......Page 19
Infection control......Page 21
Lassa fever......Page 22
Dengue haemorrhagic fever......Page 25
Dengue fever......Page 26
Western equine encephalitis......Page 27
Useful websites......Page 28
At-risk groups......Page 29
Infection in pregnancy......Page 30
Infection control......Page 32
Symptoms......Page 33
Complications......Page 34
Infection control......Page 35
Infectious period......Page 36
Clinical......Page 37
Prophylaxis......Page 38
Infection control......Page 39
Infectious period......Page 40
Pre-exposure......Page 41
Infection control......Page 43
Infectious period......Page 44
Neonatal hepatitis B......Page 45
Laboratory diagnosis......Page 46
Chronic infection......Page 47
Pre-exposure prophylaxis......Page 48
Hepatitis D (Hepatitis delta)......Page 51
Route of spread......Page 53
Symptoms......Page 54
Management......Page 55
Infection control......Page 57
Infectious period......Page 58
Complications......Page 59
Infection control......Page 60
Symptoms......Page 61
Treatment......Page 64
Infection control......Page 65
Prevalence......Page 66
Clinical......Page 68
Malignancies......Page 69
HIV antibody......Page 70
HIV pro-viral DNA PCR......Page 71
Prophylaxis......Page 72
Useful website......Page 73
Symptoms......Page 74
Infection control......Page 75
Human T-cell leukaemia virus 1......Page 76
Adult T-cell leukaemia or lymphoma (ATL)......Page 78
Prophylaxis......Page 79
Infection control......Page 80
Prevalence......Page 81
Differential diagnosis......Page 82
Treatment......Page 83
Infection control......Page 84
At-risk groups......Page 85
Laboratory diagnosis......Page 86
Infection control......Page 88
Acute parotitis......Page 89
Central nervous system complications......Page 90
Infection control......Page 91
Symptoms......Page 92
Infection control......Page 93
Differential diagnosis......Page 94
Infection control......Page 95
Prevalence......Page 96
Common warts (verrucae vulgaris) HPV types 1, 2, 4......Page 97
Other cancers......Page 98
Prophylaxis......Page 103
Polyomavirus hominis 2 or JC virus......Page 104
Simian virus 40 (SV 40)......Page 105
At-risk groups......Page 106
Infection in patients with haemolytic anaemia......Page 107
Infection control......Page 109
Smallpox......Page 110
Monkeypox......Page 111
Laboratory diagnosis......Page 112
At-risk groups......Page 114
Prophylaxis......Page 115
Infection control......Page 116
At-risk groups......Page 117
Treatment......Page 118
Infection control......Page 119
Symptoms......Page 120
Infection control......Page 121
At-risk groups......Page 122
Differential diagnosis......Page 123
Infection control......Page 124
At-risk groups......Page 125
Treatment......Page 126
Infection control......Page 128
Infectious period......Page 129
Treatment......Page 130
Useful website......Page 131
At-risk groups......Page 132
Differential diagnosis......Page 133
Infection control......Page 134
Epidemiology......Page 137
Genital chlamydia infection......Page 138
Ch. psittaci......Page 139
Laboratory diagnosis......Page 140
Infection control......Page 141
Symptoms......Page 142
Treatment......Page 143
Infection control......Page 144
Pathogenesis of prion disease......Page 145
Prevalence......Page 146
Creutzfeld-Jakob disease (CJD)......Page 147
Infection control......Page 148
Post-infectious encephalitis......Page 149
Viral meningitis......Page 150
Laboratory diagnosis......Page 151
Keratitis......Page 153
Control of infection......Page 156
Infectious period......Page 157
Symptoms......Page 158
Infection control......Page 159
Influenza......Page 160
Other respiratory viruses......Page 161
Infection control......Page 162
Mycoplasma pneumoniae......Page 163
Coxiella burnetii......Page 164
Legionella pneumophila......Page 165
Epidemiology......Page 166
Treatment......Page 168
Differential diagnosis......Page 169
Laboratory investigations......Page 173
Management......Page 175
Non-vesicular or non-ulcerative genital lesions......Page 176
Cervicitis and vaginal discharge......Page 177
Serology......Page 178
Prophylaxis and control of infection......Page 179
Diagnosis......Page 180
Human parvovirus B19......Page 182
Human herpes viruses types 6 and 7......Page 183
Herpes simplex virus (HSV)......Page 184
Varicella-zoster virus (VZV)......Page 185
Enteroviruses......Page 186
Wart-like rashes......Page 187
Haemorrhagic rashes......Page 188
Perinatal infection......Page 189
Cytomegalovirus (CMV)......Page 192
Maternal chickenpox......Page 193
Toxoplasma gondii......Page 195
Herpes simplex......Page 196
Management of maternal genital herpes infection......Page 197
Follow up of babies suspected of vertically acquired infection......Page 198
Laboratory diagnosis......Page 199
Varicella-zoster virus (VZV)......Page 200
Cytomegalovirus (CMV)......Page 203
Papilloma viruses......Page 204
Polyoma viruses......Page 205
Toxoplasma gondii......Page 208
How do viruses cause cancer?......Page 209
Burkitts lymphoma (BL)......Page 210
Hepatocellular carcinoma (HCC)......Page 211
Post-transplant lymphoproliferative disease (PTLD)......Page 212
Control of viral malignancies......Page 213
Pyrexia of unknown origin (PUO)......Page 214
Hepatitis......Page 215
Miscellaneous infections......Page 216
Filling in the specimen request form correctly......Page 217
Packaging specimens correctly......Page 218
Ideal specimen request form......Page 219
47 Serological techniques......Page 220
Enzyme-linked immunosorbent assays (EIA or ELISA)......Page 221
Immunofluorescence tests (IF or IFT)......Page 223
Complement fixation test (CFT)......Page 224
Automation in serology......Page 225
Conclusion......Page 226
Virus or cell culture......Page 227
Electron microscopy......Page 230
Viral genome detection (RNA or DNA) by molecular techniques......Page 232
Polymerase chain reaction (PCR)......Page 233
Technical consideration for molecular assays......Page 234
Future of molecular assays......Page 235
Mechanism of action......Page 237
Resistance......Page 238
Cidofovir......Page 239
Oseltamivir and zanamivir......Page 240
Antiretrovirals......Page 241
Useful websites......Page 247
Attenuated vaccines......Page 248
Vaccination programmes......Page 249
Useful websites......Page 254
Bloodborne......Page 255
Universal precautions......Page 256
Outbreaks......Page 260
Notifiable infections......Page 261
Pre-employment health check......Page 262
Needle-stick injuries......Page 263
Outbreak control......Page 265
Index......Page 266
