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Chromosomal Instability and Aging: Basic Science and Clinical Implications

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This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability and ageing. It includes in-depth discussions of various types of DNA damage, the DNA repair network, and cellular responses to genetic damage to assess their impact on the modulation of ageing processes and age-related disease, including cancer development.

Author(s): Fuki Hisama, Sherman M. Weissman, George M. Martin
Edition: 1
Year: 2003

Language: English
Pages: 600